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Items: 1 to 20 of 121

1.

Phagocytosis-dependent ketogenesis in retinal pigment epithelium.

Reyes-Reveles J, Dhingra A, Alexander D, Bragin A, Philp NJ, Boesze-Battaglia K.

J Biol Chem. 2017 May 12;292(19):8038-8047. doi: 10.1074/jbc.M116.770784. Epub 2017 Mar 16.

2.

The retinal pigment epithelium utilizes fatty acids for ketogenesis.

Adijanto J, Du J, Moffat C, Seifert EL, Hurle JB, Philp NJ.

J Biol Chem. 2014 Jul 25;289(30):20570-82.

3.

Expression of ABCA4 in the retinal pigment epithelium and its implications for Stargardt macular degeneration.

Lenis TL, Hu J, Ng SY, Jiang Z, Sarfare S, Lloyd MB, Esposito NJ, Samuel W, Jaworski C, Bok D, Finnemann SC, Radeke MJ, Redmond TM, Travis GH, Radu RA.

Proc Natl Acad Sci U S A. 2018 Nov 20;115(47):E11120-E11127. doi: 10.1073/pnas.1802519115. Epub 2018 Nov 5.

4.

The Contribution of Melanoregulin to Microtubule-Associated Protein 1 Light Chain 3 (LC3) Associated Phagocytosis in Retinal Pigment Epithelium.

Frost LS, Lopes VS, Bragin A, Reyes-Reveles J, Brancato J, Cohen A, Mitchell CH, Williams DS, Boesze-Battaglia K.

Mol Neurobiol. 2015 Dec;52(3):1135-1151. doi: 10.1007/s12035-014-8920-5. Epub 2014 Oct 10.

5.

Mertk drives myosin II redistribution during retinal pigment epithelial phagocytosis.

Strick DJ, Feng W, Vollrath D.

Invest Ophthalmol Vis Sci. 2009 May;50(5):2427-35. doi: 10.1167/iovs.08-3058. Epub 2008 Dec 30.

PMID:
19117932
6.

Phagosome maturation during endosome interaction revealed by partial rhodopsin processing in retinal pigment epithelium.

Wavre-Shapton ST, Meschede IP, Seabra MC, Futter CE.

J Cell Sci. 2014 Sep 1;127(Pt 17):3852-61. doi: 10.1242/jcs.154757. Epub 2014 Jul 29.

7.

Independent roles of methionine sulfoxide reductase A in mitochondrial ATP synthesis and as antioxidant in retinal pigment epithelial cells.

Dun Y, Vargas J, Brot N, Finnemann SC.

Free Radic Biol Med. 2013 Dec;65:1340-1351. doi: 10.1016/j.freeradbiomed.2013.10.006. Epub 2013 Oct 10.

8.

Regulation of Phagolysosomal Digestion by Caveolin-1 of the Retinal Pigment Epithelium Is Essential for Vision.

Sethna S, Chamakkala T, Gu X, Thompson TC, Cao G, Elliott MH, Finnemann SC.

J Biol Chem. 2016 Mar 18;291(12):6494-506. doi: 10.1074/jbc.M115.687004. Epub 2016 Jan 26.

9.
10.

Complement system dysregulation and inflammation in the retinal pigment epithelium of a mouse model for Stargardt macular degeneration.

Radu RA, Hu J, Yuan Q, Welch DL, Makshanoff J, Lloyd M, McMullen S, Travis GH, Bok D.

J Biol Chem. 2011 May 27;286(21):18593-601. doi: 10.1074/jbc.M110.191866. Epub 2011 Apr 4.

11.

Mitochondrial oxidative stress in the retinal pigment epithelium leads to localized retinal degeneration.

Mao H, Seo SJ, Biswal MR, Li H, Conners M, Nandyala A, Jones K, Le YZ, Lewin AS.

Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4613-27. doi: 10.1167/iovs.14-14633.

12.

Semaphorin4D-PlexinB1 Signaling Attenuates Photoreceptor Outer Segment Phagocytosis by Reducing Rac1 Activity of RPE Cells.

Bulloj A, Maminishkis A, Mizui M, Finnemann SC.

Mol Neurobiol. 2018 May;55(5):4320-4332. doi: 10.1007/s12035-017-0649-5. Epub 2017 Jun 17.

13.

Photoreceptor phagosome processing defects and disturbed autophagy in retinal pigment epithelium of Cln3Δex1-6 mice modelling juvenile neuronal ceroid lipofuscinosis (Batten disease).

Wavre-Shapton ST, Calvi AA, Turmaine M, Seabra MC, Cutler DF, Futter CE, Mitchison HM.

Hum Mol Genet. 2015 Dec 15;24(24):7060-74. doi: 10.1093/hmg/ddv406. Epub 2015 Oct 8.

14.

Microtubule-Associated Protein 1 Light Chain 3B, (LC3B) Is Necessary to Maintain Lipid-Mediated Homeostasis in the Retinal Pigment Epithelium.

Dhingra A, Bell BA, Peachey NS, Daniele LL, Reyes-Reveles J, Sharp RC, Jun B, Bazan NG, Sparrow JR, Kim HJ, Philp NJ, Boesze-Battaglia K.

Front Cell Neurosci. 2018 Oct 8;12:351. doi: 10.3389/fncel.2018.00351. eCollection 2018.

15.

MERTK signaling in the retinal pigment epithelium regulates the tyrosine phosphorylation of GDP dissociation inhibitor alpha from the GDI/CHM family of RAB GTPase effectors.

Shelby SJ, Feathers KL, Ganios AM, Jia L, Miller JM, Thompson DA.

Exp Eye Res. 2015 Nov;140:28-40. doi: 10.1016/j.exer.2015.08.006. Epub 2015 Aug 15.

16.

Live-Cell Imaging of Phagosome Motility in Primary Mouse RPE Cells.

Hazim R, Jiang M, Esteve-Rudd J, Diemer T, Lopes VS, Williams DS.

Adv Exp Med Biol. 2016;854:751-5. doi: 10.1007/978-3-319-17121-0_100.

PMID:
26427485
17.

CaV1.3 L-type channels, maxiK Ca(2+)-dependent K(+) channels and bestrophin-1 regulate rhythmic photoreceptor outer segment phagocytosis by retinal pigment epithelial cells.

Müller C, Más Gómez N, Ruth P, Strauss O.

Cell Signal. 2014 May;26(5):968-78. doi: 10.1016/j.cellsig.2013.12.021. Epub 2014 Jan 7.

PMID:
24407175
18.

RUBCN/rubicon and EGFR regulate lysosomal degradative processes in the retinal pigment epithelium (RPE) of the eye.

Muniz-Feliciano L, Doggett TA, Zhou Z, Ferguson TA.

Autophagy. 2017;13(12):2072-2085. doi: 10.1080/15548627.2017.1380124.

19.

Molecular characterization and functional analysis of phagocytosis by human embryonic stem cell-derived RPE cells using a novel human retinal assay.

Carr AJ, Vugler A, Lawrence J, Chen LL, Ahmado A, Chen FK, Semo M, Gias C, da Cruz L, Moore HD, Walsh J, Coffey PJ.

Mol Vis. 2009;15:283-95. Epub 2009 Feb 6.

20.

Defective phagosome motility and degradation in cell nonautonomous RPE pathogenesis of a dominant macular degeneration.

Esteve-Rudd J, Hazim RA, Diemer T, Paniagua AE, Volland S, Umapathy A, Williams DS.

Proc Natl Acad Sci U S A. 2018 May 22;115(21):5468-5473. doi: 10.1073/pnas.1709211115. Epub 2018 May 7.

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