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Items: 1 to 20 of 108

1.

Oncogene-Selective Sensitivity to Synchronous Cell Death following Modulation of the Amino Acid Nutrient Cystine.

Poursaitidis I, Wang X, Crighton T, Labuschagne C, Mason D, Cramer SL, Triplett K, Roy R, Pardo OE, Seckl MJ, Rowlinson SW, Stone E, Lamb RF.

Cell Rep. 2017 Mar 14;18(11):2547-2556. doi: 10.1016/j.celrep.2017.02.054.

2.

CD44 variant-dependent regulation of redox balance in EGFR mutation-positive non-small cell lung cancer: A target for treatment.

Kawano Y, Iwama E, Tsuchihashi K, Shibahara D, Harada T, Tanaka K, Nagano O, Saya H, Nakanishi Y, Okamoto I.

Lung Cancer. 2017 Nov;113:72-78. doi: 10.1016/j.lungcan.2017.09.008. Epub 2017 Sep 14.

PMID:
29110853
3.

Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis.

Yang WS, Kim KJ, Gaschler MM, Patel M, Shchepinov MS, Stockwell BR.

Proc Natl Acad Sci U S A. 2016 Aug 23;113(34):E4966-75. doi: 10.1073/pnas.1603244113. Epub 2016 Aug 9.

4.

Lipid Peroxidation-Dependent Cell Death Regulated by GPx4 and Ferroptosis.

Imai H, Matsuoka M, Kumagai T, Sakamoto T, Koumura T.

Curr Top Microbiol Immunol. 2017;403:143-170. doi: 10.1007/82_2016_508. Review.

PMID:
28204974
5.

Ferroptosis: Role of lipid peroxidation, iron and ferritinophagy.

Latunde-Dada GO.

Biochim Biophys Acta Gen Subj. 2017 Aug;1861(8):1893-1900. doi: 10.1016/j.bbagen.2017.05.019. Epub 2017 May 24. Review.

PMID:
28552631
6.

Extracellular cysteine/cystine redox regulates the p44/p42 MAPK pathway by metalloproteinase-dependent epidermal growth factor receptor signaling.

Nkabyo YS, Go YM, Ziegler TR, Jones DP.

Am J Physiol Gastrointest Liver Physiol. 2005 Jul;289(1):G70-8. Epub 2005 Mar 3.

7.

Gefitinib-induced killing of NSCLC cell lines expressing mutant EGFR requires BIM and can be enhanced by BH3 mimetics.

Cragg MS, Kuroda J, Puthalakath H, Huang DC, Strasser A.

PLoS Med. 2007 Oct;4(10):1681-89; discussion 1690.

8.
9.

Low-density lipoprotein docosahexaenoic acid nanoparticles induce ferroptotic cell death in hepatocellular carcinoma.

Ou W, Mulik RS, Anwar A, McDonald JG, He X, Corbin IR.

Free Radic Biol Med. 2017 Nov;112:597-607. doi: 10.1016/j.freeradbiomed.2017.09.002. Epub 2017 Sep 8.

11.

ERK1/2 blockade prevents epithelial-mesenchymal transition in lung cancer cells and promotes their sensitivity to EGFR inhibition.

Buonato JM, Lazzara MJ.

Cancer Res. 2014 Jan 1;74(1):309-19. doi: 10.1158/0008-5472.CAN-12-4721. Epub 2013 Oct 9.

13.

Differential regulation of epidermal growth factor receptor by hydrogen peroxide and flagellin in cultured lung alveolar epithelial cells.

Nishi H, Maeda N, Izumi S, Higa-Nakamine S, Toku S, Kakinohana M, Sugahara K, Yamamoto H.

Eur J Pharmacol. 2015 Feb 5;748:133-42. doi: 10.1016/j.ejphar.2014.12.016. Epub 2014 Dec 24.

PMID:
25542757
14.

Induction of ferroptotic cell death for overcoming cisplatin resistance of head and neck cancer.

Roh JL, Kim EH, Jang HJ, Park JY, Shin D.

Cancer Lett. 2016 Oct 10;381(1):96-103. doi: 10.1016/j.canlet.2016.07.035. Epub 2016 Jul 28.

PMID:
27477897
15.

EGFR inhibition evokes innate drug resistance in lung cancer cells by preventing Akt activity and thus inactivating Ets-1 function.

Phuchareon J, McCormick F, Eisele DW, Tetsu O.

Proc Natl Acad Sci U S A. 2015 Jul 21;112(29):E3855-63. doi: 10.1073/pnas.1510733112. Epub 2015 Jul 6.

16.

Activity of panitumumab alone or with chemotherapy in non-small cell lung carcinoma cell lines expressing mutant epidermal growth factor receptor.

Freeman DJ, Bush T, Ogbagabriel S, Belmontes B, Juan T, Plewa C, Van G, Johnson C, Radinsky R.

Mol Cancer Ther. 2009 Jun;8(6):1536-46. doi: 10.1158/1535-7163.MCT-08-0978. Epub 2009 Jun 9.

17.

Apoptosis induced by depsipeptide FK228 coincides with inhibition of survival signaling in lung cancer cells.

Yu XD, Wang SY, Chen GA, Hou CM, Zhao M, Hong JA, Nguyen DM, Schrump DS.

Cancer J. 2007 Mar-Apr;13(2):105-13.

PMID:
17476138
18.

Ferroptosis is associated with oxygen-glucose deprivation/reoxygenation-induced Sertoli cell death.

Li L, Hao Y, Zhao Y, Wang H, Zhao X, Jiang Y, Gao F.

Int J Mol Med. 2018 May;41(5):3051-3062. doi: 10.3892/ijmm.2018.3469. Epub 2018 Feb 7.

PMID:
29436589
19.

Resistance to RET-Inhibition in RET-Rearranged NSCLC Is Mediated By Reactivation of RAS/MAPK Signaling.

Nelson-Taylor SK, Le AT, Yoo M, Schubert L, Mishall KM, Doak A, Varella-Garcia M, Tan AC, Doebele RC.

Mol Cancer Ther. 2017 Aug;16(8):1623-1633. doi: 10.1158/1535-7163.MCT-17-0008. Epub 2017 May 12.

20.

244-MPT overcomes gefitinib resistance in non-small cell lung cancer cells.

Zhang Y, Yao K, Shi C, Jiang Y, Liu K, Zhao S, Chen H, Reddy K, Zhang C, Chang X, Ryu J, Bode AM, Dong Z, Dong Z.

Oncotarget. 2015 Dec 29;6(42):44274-88. doi: 10.18632/oncotarget.6236.

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