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Items: 1 to 20 of 102

1.

A human monoclonal antibody that specifically binds and inhibits the staphylococcal complement inhibitor protein SCIN.

Hoekstra H, Romero Pastrana F, Bonarius HPJ, van Kessel KPM, Elsinga GS, Kooi N, Groen H, van Dijl JM, Buist G.

Virulence. 2018 Jan 1;9(1):70-82. doi: 10.1080/21505594.2017.1294297. Epub 2017 May 8.

2.

Identification of a staphylococcal complement inhibitor with broad host specificity in equid Staphylococcus aureus strains.

de Jong NWM, Vrieling M, Garcia BL, Koop G, Brettmann M, Aerts PC, Ruyken M, van Strijp JAG, Holmes M, Harrison EM, Geisbrecht BV, Rooijakkers SHM.

J Biol Chem. 2018 Mar 23;293(12):4468-4477. doi: 10.1074/jbc.RA117.000599. Epub 2018 Feb 5.

3.

Diversity in the C3b [corrected] contact residues and tertiary structures of the staphylococcal complement inhibitor (SCIN) protein family.

Garcia BL, Summers BJ, Lin Z, Ramyar KX, Ricklin D, Kamath DV, Fu ZQ, Lambris JD, Geisbrecht BV.

J Biol Chem. 2012 Jan 2;287(1):628-40. doi: 10.1074/jbc.M111.298984. Epub 2011 Nov 15. Erratum in: J Biol Chem. 2012 Mar 16;287(12):9329.

4.

Staphylococcal complement inhibitor modulates phagocyte responses by dimerization of convertases.

Jongerius I, Puister M, Wu J, Ruyken M, van Strijp JA, Rooijakkers SH.

J Immunol. 2010 Jan 1;184(1):420-5. doi: 10.4049/jimmunol.0902865. Epub 2009 Nov 30.

5.

A molecular insight into complement evasion by the staphylococcal complement inhibitor protein family.

Ricklin D, Tzekou A, Garcia BL, Hammel M, McWhorter WJ, Sfyroera G, Wu YQ, Holers VM, Herbert AP, Barlow PN, Geisbrecht BV, Lambris JD.

J Immunol. 2009 Aug 15;183(4):2565-74. doi: 10.4049/jimmunol.0901443. Epub 2009 Jul 22.

6.

Molecular basis for complement recognition and inhibition determined by crystallographic studies of the staphylococcal complement inhibitor (SCIN) bound to C3c and C3b.

Garcia BL, Ramyar KX, Tzekou A, Ricklin D, McWhorter WJ, Lambris JD, Geisbrecht BV.

J Mol Biol. 2010 Sep 10;402(1):17-29. doi: 10.1016/j.jmb.2010.07.029. Epub 2010 Jul 21.

7.

Identification of peptidic inhibitors of the alternative complement pathway based on Staphylococcus aureus SCIN proteins.

Summers BJ, Garcia BL, Woehl JL, Ramyar KX, Yao X, Geisbrecht BV.

Mol Immunol. 2015 Oct;67(2 Pt B):193-205. doi: 10.1016/j.molimm.2015.05.012. Epub 2015 Jun 4.

8.

A structurally dynamic N-terminal helix is a key functional determinant in staphylococcal complement inhibitor (SCIN) proteins.

Garcia BL, Summers BJ, Ramyar KX, Tzekou A, Lin Z, Ricklin D, Lambris JD, Laity JH, Geisbrecht BV.

J Biol Chem. 2013 Jan 25;288(4):2870-81. doi: 10.1074/jbc.M112.426858. Epub 2012 Dec 11.

9.

The Staphylococcus aureus protein Sbi acts as a complement inhibitor and forms a tripartite complex with host complement Factor H and C3b.

Haupt K, Reuter M, van den Elsen J, Burman J, Hälbich S, Richter J, Skerka C, Zipfel PF.

PLoS Pathog. 2008 Dec;4(12):e1000250. doi: 10.1371/journal.ppat.1000250. Epub 2008 Dec 26.

10.

Production of Staphylococcal Complement Inhibitor (SCIN) and Other Immune Modulators during the Early Stages of Staphylococcus aureus Biofilm Formation in a Mammalian Cell Culture Medium.

Sultan AR, Swierstra JW, Lemmens-den Toom NA, Snijders SV, Hansenová Maňásková S, Verbon A, van Wamel WJB.

Infect Immun. 2018 Jul 23;86(8). pii: e00352-18. doi: 10.1128/IAI.00352-18. Print 2018 Aug.

11.

Early expression of SCIN and CHIPS drives instant immune evasion by Staphylococcus aureus.

Rooijakkers SH, Ruyken M, van Roon J, van Kessel KP, van Strijp JA, van Wamel WJ.

Cell Microbiol. 2006 Aug;8(8):1282-93.

PMID:
16882032
12.

Staphylococcal complement inhibitor: structure and active sites.

Rooijakkers SH, Milder FJ, Bardoel BW, Ruyken M, van Strijp JA, Gros P.

J Immunol. 2007 Sep 1;179(5):2989-98.

13.

Crystallization of human complement component C3b in the presence of a staphylococcal complement-inhibitor protein (SCIN).

Garcia BL, Tzekou A, Ramyar KX, McWhorter WJ, Ricklin D, Lambris JD, Geisbrecht BV.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 May 1;65(Pt 5):482-5. doi: 10.1107/S174430910901207X. Epub 2009 Apr 24.

14.

Staphylococcus aureus metalloprotease aureolysin cleaves complement C3 to mediate immune evasion.

Laarman AJ, Ruyken M, Malone CL, van Strijp JA, Horswill AR, Rooijakkers SH.

J Immunol. 2011 Jun 1;186(11):6445-53. doi: 10.4049/jimmunol.1002948. Epub 2011 Apr 18.

15.

Structural and functional implications of the alternative complement pathway C3 convertase stabilized by a staphylococcal inhibitor.

Rooijakkers SH, Wu J, Ruyken M, van Domselaar R, Planken KL, Tzekou A, Ricklin D, Lambris JD, Janssen BJ, van Strijp JA, Gros P.

Nat Immunol. 2009 Jul;10(7):721-7. doi: 10.1038/ni.1756. Epub 2009 Jun 7.

16.

Staphylococcal complement evasion by various convertase-blocking molecules.

Jongerius I, Köhl J, Pandey MK, Ruyken M, van Kessel KP, van Strijp JA, Rooijakkers SH.

J Exp Med. 2007 Oct 1;204(10):2461-71. Epub 2007 Sep 24.

17.

Noninvasive optical and nuclear imaging of Staphylococcus-specific infection with a human monoclonal antibody-based probe.

Romero Pastrana F, Thompson JM, Heuker M, Hoekstra H, Dillen CA, Ortines RV, Ashbaugh AG, Pickett JE, Linssen MD, Bernthal NM, Francis KP, Buist G, van Oosten M, van Dam GM, Thorek DLJ, Miller LS, van Dijl JM.

Virulence. 2018 Jan 1;9(1):262-272. doi: 10.1080/21505594.2017.1403004. Epub 2017 Dec 26.

18.

Differential epitope recognition in the immunodominant staphylococcal antigen A of Staphylococcus aureus by mouse versus human IgG antibodies.

Koedijk DGAM, Pastrana FR, Hoekstra H, Berg SVD, Back JW, Kerstholt C, Prins RC, Bakker-Woudenberg IAJM, van Dijl JM, Buist G.

Sci Rep. 2017 Aug 15;7(1):8141. doi: 10.1038/s41598-017-08182-9.

19.

IgG4 subclass-specific responses to Staphylococcus aureus antigens shed new light on host-pathogen interaction.

Swierstra J, Debets S, de Vogel C, Lemmens-den Toom N, Verkaik N, Ramdani-Bouguessa N, Jonkman MF, van Dijl JM, Fahal A, van Belkum A, van Wamel W.

Infect Immun. 2015 Feb;83(2):492-501. doi: 10.1128/IAI.02286-14. Epub 2014 Nov 17.

20.

Staphylococcal Ecb protein and host complement regulator factor H enhance functions of each other in bacterial immune evasion.

Amdahl H, Jongerius I, Meri T, Pasanen T, Hyvärinen S, Haapasalo K, van Strijp JA, Rooijakkers SH, Jokiranta TS.

J Immunol. 2013 Aug 15;191(4):1775-84. doi: 10.4049/jimmunol.1300638. Epub 2013 Jul 17.

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