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Items: 1 to 20 of 88

1.

Homozygous mutation in TXNRD1 is associated with genetic generalized epilepsy.

Kudin AP, Baron G, Zsurka G, Hampel KG, Elger CE, Grote A, Weber Y, Lerche H, Thiele H, Nürnberg P, Schulz H, Ruppert AK, Sander T, Cheng Q, Arnér ES, Schomburg L, Seeher S, Fradejas-Villar N, Schweizer U, Kunz WS.

Free Radic Biol Med. 2017 May;106:270-277. doi: 10.1016/j.freeradbiomed.2017.02.040. Epub 2017 Feb 21.

PMID:
28232204
2.

Loss of thioredoxin reductase 1 renders tumors highly susceptible to pharmacologic glutathione deprivation.

Mandal PK, Schneider M, Kölle P, Kuhlencordt P, Förster H, Beck H, Bornkamm GW, Conrad M.

Cancer Res. 2010 Nov 15;70(22):9505-14. doi: 10.1158/0008-5472.CAN-10-1509. Epub 2010 Nov 2.

3.

A Txnrd1-dependent metabolic switch alters hepatic lipogenesis, glycogen storage, and detoxification.

Iverson SV, Eriksson S, Xu J, Prigge JR, Talago EA, Meade TA, Meade ES, Capecchi MR, Arnér ES, Schmidt EE.

Free Radic Biol Med. 2013 Oct;63:369-80. doi: 10.1016/j.freeradbiomed.2013.05.028. Epub 2013 Jun 3.

4.

Effect of selenium on thioredoxin reductase activity in Txnrd1 or Txnrd2 hemizygous mice.

Kiermayer C, Michalke B, Schmidt J, Brielmeier M.

Biol Chem. 2007 Oct;388(10):1091-7.

PMID:
17937623
5.

Selenium supplementation of lung epithelial cells enhances nuclear factor E2-related factor 2 (Nrf2) activation following thioredoxin reductase inhibition.

Tindell R, Wall SB, Li Q, Li R, Dunigan K, Wood R, Tipple TE.

Redox Biol. 2018 Oct;19:331-338. doi: 10.1016/j.redox.2018.07.020. Epub 2018 Sep 5. Erratum in: Redox Biol. 2020 Jan;28:.

6.

Role of thioredoxin reductase 1 and thioredoxin interacting protein in prognosis of breast cancer.

Cadenas C, Franckenstein D, Schmidt M, Gehrmann M, Hermes M, Geppert B, Schormann W, Maccoux LJ, Schug M, Schumann A, Wilhelm C, Freis E, Ickstadt K, Rahnenführer J, Baumbach JI, Sickmann A, Hengstler JG.

Breast Cancer Res. 2010;12(3):R44. doi: 10.1186/bcr2599. Epub 2010 Jun 28.

7.

The expression and activity of thioredoxin reductase 1 splice variants v1 and v2 regulate the expression of genes associated with differentiation and adhesion.

Nalvarte I, Damdimopoulos AE, Rüegg J, Spyrou G.

Biosci Rep. 2015 Oct 13;35(6). pii: e00269. doi: 10.1042/BSR20150236.

8.

Hepatocyte DNA replication in growing liver requires either glutathione or a single allele of txnrd1.

Prigge JR, Eriksson S, Iverson SV, Meade TA, Capecchi MR, Arnér ES, Schmidt EE.

Free Radic Biol Med. 2012 Feb 15;52(4):803-10. doi: 10.1016/j.freeradbiomed.2011.11.025. Epub 2011 Dec 8.

9.

A novel inherited mutation in the voltage sensor region of SCN1A is associated with Panayiotopoulos syndrome in siblings and generalized epilepsy with febrile seizures plus.

Livingston JH, Cross JH, Mclellan A, Birch R, Zuberi SM.

J Child Neurol. 2009 Apr;24(4):503-8. doi: 10.1177/0883073808324537.

PMID:
19339291
10.

Generalized verrucosis and abnormal T cell activation due to homozygous TAOK2 mutation.

Molho-Pessach V, Ramot Y, Mogilevsky M, Cohen-Daniel L, Eisenstein EM, Abu-Libdeh A, Siam I, Berger M, Karni R, Zlotogorski A.

J Dermatol Sci. 2017 Aug;87(2):123-129. doi: 10.1016/j.jdermsci.2017.03.018. Epub 2017 Mar 27.

PMID:
28385331
11.

Thioredoxin reductase-1 mediates curcumin-induced radiosensitization of squamous carcinoma cells.

Javvadi P, Hertan L, Kosoff R, Datta T, Kolev J, Mick R, Tuttle SW, Koumenis C.

Cancer Res. 2010 Mar 1;70(5):1941-50. doi: 10.1158/0008-5472.CAN-09-3025. Epub 2010 Feb 16.

12.

Sec-containing TrxR1 is essential for self-sufficiency of cells by control of glucose-derived H2O2.

Peng X, Mandal PK, Kaminskyy VO, Lindqvist A, Conrad M, Arnér ES.

Cell Death Dis. 2014 May 22;5:e1235. doi: 10.1038/cddis.2014.209.

13.

An integrative genomics approach identifies activation of thioredoxin/thioredoxin reductase-1-mediated oxidative stress defense pathway and inhibition of angiogenesis in obese nondiabetic human subjects.

Das SK, Sharma NK, Hasstedt SJ, Mondal AK, Ma L, Langberg KA, Elbein SC.

J Clin Endocrinol Metab. 2011 Aug;96(8):E1308-13. doi: 10.1210/jc.2011-0101. Epub 2011 May 18.

14.

The production of reactive oxygen species enhanced with the reduction of menadione by active thioredoxin reductase.

Li J, Zuo X, Cheng P, Ren X, Sun S, Xu J, Holmgren A, Lu J.

Metallomics. 2019 Sep 1;11(9):1490-1497. doi: 10.1039/c9mt00133f. Epub 2019 Jul 30.

PMID:
31359011
15.

ROS signaling by NOX4 drives fibroblast-to-myofibroblast differentiation in the diseased prostatic stroma.

Sampson N, Koziel R, Zenzmaier C, Bubendorf L, Plas E, Jansen-Dürr P, Berger P.

Mol Endocrinol. 2011 Mar;25(3):503-15. doi: 10.1210/me.2010-0340. Epub 2011 Jan 27.

16.

Association between TXNRD1 polymorphisms and anti-tuberculosis drug-induced hepatotoxicity in a prospective study.

Ji GY, Wang Y, Wu SQ, Liu QQ, Wu JC, Zhang MM, Sandford AJ, He JQ.

Genet Mol Res. 2016 Sep 2;15(3). doi: 10.4238/gmr.15038296.

PMID:
27706680
17.

Novel mutation of SCN1A in familial generalized epilepsy with febrile seizures plus.

Li N, Zhang J, Guo JF, Yan XX, Xia K, Tang BS.

Neurosci Lett. 2010 Aug 23;480(3):211-4. doi: 10.1016/j.neulet.2010.06.040. Epub 2010 Jun 18.

PMID:
20600615
18.

Cytoplasmic thioredoxin reductase is essential for embryogenesis but dispensable for cardiac development.

Jakupoglu C, Przemeck GK, Schneider M, Moreno SG, Mayr N, Hatzopoulos AK, de Angelis MH, Wurst W, Bornkamm GW, Brielmeier M, Conrad M.

Mol Cell Biol. 2005 Mar;25(5):1980-8.

19.

Induction of cell membrane protrusions by the N-terminal glutaredoxin domain of a rare splice variant of human thioredoxin reductase 1.

Dammeyer P, Damdimopoulos AE, Nordman T, Jiménez A, Miranda-Vizuete A, Arnér ES.

J Biol Chem. 2008 Feb 1;283(5):2814-21. Epub 2007 Nov 27.

20.

TXNRD1 Is an Unfavorable Prognostic Factor for Patients with Hepatocellular Carcinoma.

Fu B, Meng W, Zeng X, Zhao H, Liu W, Zhang T.

Biomed Res Int. 2017;2017:4698167. doi: 10.1155/2017/4698167. Epub 2017 Apr 27.

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