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Items: 1 to 20 of 140

1.

Neutrophils and neutrophil serine proteases are increased in the spleens of estrogen-treated C57BL/6 mice and several strains of spontaneous lupus-prone mice.

Dai R, Cowan C, Heid B, Khan D, Liang Z, Pham CT, Ahmed SA.

PLoS One. 2017 Feb 13;12(2):e0172105. doi: 10.1371/journal.pone.0172105. eCollection 2017.

2.

Serine protease inhibitor, 4-(2-aminoethyl)-benzene sulfonyl fluoride, impairs IL-12-induced activation of pSTAT4β, NFκB, and select pro-inflammatory mediators from estrogen-treated mice.

Karpuzoglu E, Gogal RM Jr, Ansar Ahmed S.

Immunobiology. 2011 Dec;216(12):1264-73. doi: 10.1016/j.imbio.2011.07.003. Epub 2011 Jul 7.

PMID:
21813204
3.

Unopposed cathepsin G, neutrophil elastase, and proteinase 3 cause severe lung damage and emphysema.

Guyot N, Wartelle J, Malleret L, Todorov AA, Devouassoux G, Pacheco Y, Jenne DE, Belaaouaj A.

Am J Pathol. 2014 Aug;184(8):2197-210. doi: 10.1016/j.ajpath.2014.04.015. Epub 2014 Jun 12.

PMID:
24929239
4.

Neutrophil serine proteases promote IL-1β generation and injury in necrotizing crescentic glomerulonephritis.

Schreiber A, Pham CT, Hu Y, Schneider W, Luft FC, Kettritz R.

J Am Soc Nephrol. 2012 Mar;23(3):470-82. doi: 10.1681/ASN.2010080892. Epub 2012 Jan 12.

5.

Mechanism of neutrophil dysfunction: neutrophil serine proteases cleave and inactivate the C5a receptor.

van den Berg CW, Tambourgi DV, Clark HW, Hoong SJ, Spiller OB, McGreal EP.

J Immunol. 2014 Feb 15;192(4):1787-95. doi: 10.4049/jimmunol.1301920. Epub 2014 Jan 20.

6.

Neutrophil serine proteases exert proteolytic activity on endothelial cells.

Jerke U, Hernandez DP, Beaudette P, Korkmaz B, Dittmar G, Kettritz R.

Kidney Int. 2015 Oct;88(4):764-75. doi: 10.1038/ki.2015.159. Epub 2015 Jun 10.

PMID:
26061547
7.

Tailor-made inflammation: how neutrophil serine proteases modulate the inflammatory response.

Kessenbrock K, Dau T, Jenne DE.

J Mol Med (Berl). 2011 Jan;89(1):23-8. doi: 10.1007/s00109-010-0677-3. Epub 2010 Aug 31. Review.

8.

Measurement of neutrophil elastase, proteinase 3, and cathepsin G activities using intramolecularly quenched fluorogenic substrates.

Korkmaz B, Attucci S, Epinette C, Pitois E, Jourdan ML, Juliano L, Gauthier F.

Methods Mol Biol. 2012;844:125-38. doi: 10.1007/978-1-61779-527-5_9.

PMID:
22262439
9.
10.

Proteinase 3 and neutrophil elastase enhance inflammation in mice by inactivating antiinflammatory progranulin.

Kessenbrock K, Fröhlich L, Sixt M, Lämmermann T, Pfister H, Bateman A, Belaaouaj A, Ring J, Ollert M, Fässler R, Jenne DE.

J Clin Invest. 2008 Jul;118(7):2438-47. doi: 10.1172/JCI34694.

11.

Lung inflammation promotes metastasis through neutrophil protease-mediated degradation of Tsp-1.

El Rayes T, Catena R, Lee S, Stawowczyk M, Joshi N, Fischbach C, Powell CA, Dannenberg AJ, Altorki NK, Gao D, Mittal V.

Proc Natl Acad Sci U S A. 2015 Dec 29;112(52):16000-5. doi: 10.1073/pnas.1507294112. Epub 2015 Dec 14.

12.

Processing of Neutrophil α-Defensins Does Not Rely on Serine Proteases In Vivo.

Glenthøj A, Nickles K, Cowland J, Borregaard N.

PLoS One. 2015 May 6;10(5):e0125483. doi: 10.1371/journal.pone.0125483. eCollection 2015.

13.

Global substrate profiling of proteases in human neutrophil extracellular traps reveals consensus motif predominantly contributed by elastase.

O'Donoghue AJ, Jin Y, Knudsen GM, Perera NC, Jenne DE, Murphy JE, Craik CS, Hermiston TW.

PLoS One. 2013 Sep 20;8(9):e75141. doi: 10.1371/journal.pone.0075141. eCollection 2013.

14.

Cathepsin G and neutrophil elastase play critical and nonredundant roles in lung-protective immunity against Streptococcus pneumoniae in mice.

Hahn I, Klaus A, Janze AK, Steinwede K, Ding N, Bohling J, Brumshagen C, Serrano H, Gauthier F, Paton JC, Welte T, Maus UA.

Infect Immun. 2011 Dec;79(12):4893-901. doi: 10.1128/IAI.05593-11. Epub 2011 Sep 12.

15.

Neutrophil Proteases Promote Experimental Abdominal Aortic Aneurysm via Extracellular Trap Release and Plasmacytoid Dendritic Cell Activation.

Yan H, Zhou HF, Akk A, Hu Y, Springer LE, Ennis TL, Pham CTN.

Arterioscler Thromb Vasc Biol. 2016 Aug;36(8):1660-1669. doi: 10.1161/ATVBAHA.116.307786. Epub 2016 Jun 9.

16.

N-Arylacyl O-sulfonated aminoglycosides as novel inhibitors of human neutrophil elastase, cathepsin G and proteinase 3.

Craciun I, Fenner AM, Kerns RJ.

Glycobiology. 2016 Jul;26(7):701-709. doi: 10.1093/glycob/cww011. Epub 2016 Feb 5.

17.

Relevance of the mouse model as a therapeutic approach for neutrophil proteinase 3-associated human diseases.

Korkmaz B, Jenne DE, Gauthier F.

Int Immunopharmacol. 2013 Dec;17(4):1198-205. doi: 10.1016/j.intimp.2013.07.003. Epub 2013 Jul 23. Review.

PMID:
23886601
18.

Neutral serine proteases of neutrophils.

Kettritz R.

Immunol Rev. 2016 Sep;273(1):232-48. doi: 10.1111/imr.12441. Review.

PMID:
27558338
19.

Neutrophil elastase cleaves laminin-332 (laminin-5) generating peptides that are chemotactic for neutrophils.

Mydel P, Shipley JM, Adair-Kirk TL, Kelley DG, Broekelmann TJ, Mecham RP, Senior RM.

J Biol Chem. 2008 Apr 11;283(15):9513-22. doi: 10.1074/jbc.M706239200. Epub 2008 Jan 4.

20.

A benzenediamine derivative fc-99 attenuates lupus-like syndrome in MRL/lpr mice related to suppression of pDC activation.

Ji J, Fan H, Li F, Li X, Dong G, Gong W, Song Y, Liu F, Hua C, Tan R, Dou H, Hou Y.

Immunol Lett. 2015 Dec;168(2):355-65. doi: 10.1016/j.imlet.2015.10.017. Epub 2015 Nov 3.

PMID:
26545567

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