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Items: 1 to 20 of 134

1.

Genetic Association and Risk Scores in a Chronic Obstructive Pulmonary Disease Meta-analysis of 16,707 Subjects.

Busch R, Hobbs BD, Zhou J, Castaldi PJ, McGeachie MJ, Hardin ME, Hawrylkiewicz I, Sliwinski P, Yim JJ, Kim WJ, Kim DK, Agusti A, Make BJ, Crapo JD, Calverley PM, Donner CF, Lomas DA, Wouters EF, Vestbo J, Tal-Singer R, Bakke P, Gulsvik A, Litonjua AA, Sparrow D, Paré PD, Levy RD, Rennard SI, Beaty TH, Hokanson J, Silverman EK, Cho MH; National Emphysema Treatment Trial Genetics; Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-Points; International COPD Genetics Network; COPDGene Investigators.

Am J Respir Cell Mol Biol. 2017 Jul;57(1):35-46. doi: 10.1165/rcmb.2016-0331OC.

2.

Sex-Based Genetic Association Study Identifies CELSR1 as a Possible Chronic Obstructive Pulmonary Disease Risk Locus among Women.

Hardin M, Cho MH, Sharma S, Glass K, Castaldi PJ, McDonald ML, Aschard H, Senter-Sylvia J, Tantisira K, Weiss ST, Hersh CP, Morrow JD, Lomas D, Agusti A, Bakke P, Gulsvik A, O'Connor GT, Dupuis J, Hokanson J, Crapo JD, Beaty TH, Laird N, Silverman EK, DeMeo DL; COPDGene and Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-Points Investigators.

Am J Respir Cell Mol Biol. 2017 Mar;56(3):332-341. doi: 10.1165/rcmb.2016-0172OC.

3.

Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis.

Cho MH, McDonald ML, Zhou X, Mattheisen M, Castaldi PJ, Hersh CP, Demeo DL, Sylvia JS, Ziniti J, Laird NM, Lange C, Litonjua AA, Sparrow D, Casaburi R, Barr RG, Regan EA, Make BJ, Hokanson JE, Lutz S, Dudenkov TM, Farzadegan H, Hetmanski JB, Tal-Singer R, Lomas DA, Bakke P, Gulsvik A, Crapo JD, Silverman EK, Beaty TH; NETT Genetics, ICGN, ECLIPSE and COPDGene Investigators.

Lancet Respir Med. 2014 Mar;2(3):214-25. doi: 10.1016/S2213-2600(14)70002-5. Epub 2014 Feb 7.

4.

Whole-Genome Sequencing in Severe Chronic Obstructive Pulmonary Disease.

Prokopenko D, Sakornsakolpat P, Fier HL, Qiao D, Parker MM, McDonald MN, Manichaikul A, Rich SS, Barr RG, Williams CJ, Brantly ML, Lange C, Beaty TH, Crapo JD, Silverman EK, Cho MH.

Am J Respir Cell Mol Biol. 2018 Nov;59(5):614-622. doi: 10.1165/rcmb.2018-0088OC.

PMID:
29949718
5.

Genetic variants in HHIP are associated with FEV1 in subjects with chronic obstructive pulmonary disease.

Kim WJ, Oh YM, Lee JH, Park CS, Park SW, Park JS, Lee SD.

Respirology. 2013 Nov;18(8):1202-9. doi: 10.1111/resp.12139.

PMID:
23731023
6.

Effect of five genetic variants associated with lung function on the risk of chronic obstructive lung disease, and their joint effects on lung function.

Soler Artigas M, Wain LV, Repapi E, Obeidat M, Sayers I, Burton PR, Johnson T, Zhao JH, Albrecht E, Dominiczak AF, Kerr SM, Smith BH, Cadby G, Hui J, Palmer LJ, Hingorani AD, Wannamethee SG, Whincup PH, Ebrahim S, Smith GD, Barroso I, Loos RJ, Wareham NJ, Cooper C, Dennison E, Shaheen SO, Liu JZ, Marchini J; Medical Research Council National Survey of Health and Development (NSHD) Respiratory Study Team, Dahgam S, Naluai AT, Olin AC, Karrasch S, Heinrich J, Schulz H, McKeever TM, Pavord ID, Heliövaara M, Ripatti S, Surakka I, Blakey JD, Kähönen M, Britton JR, Nyberg F, Holloway JW, Lawlor DA, Morris RW, James AL, Jackson CM, Hall IP, Tobin MD; SpiroMeta Consortium.

Am J Respir Crit Care Med. 2011 Oct 1;184(7):786-95. doi: 10.1164/rccm.201102-0192OC.

7.

Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease.

Kim DK, Cho MH, Hersh CP, Lomas DA, Miller BE, Kong X, Bakke P, Gulsvik A, Agustí A, Wouters E, Celli B, Coxson H, Vestbo J, MacNee W, Yates JC, Rennard S, Litonjua A, Qiu W, Beaty TH, Crapo JD, Riley JH, Tal-Singer R, Silverman EK; ECLIPSE, ICGN, and COPDGene Investigators.

Am J Respir Crit Care Med. 2012 Dec 15;186(12):1238-47. doi: 10.1164/rccm.201206-1013OC. Epub 2012 Nov 9.

8.

Childhood asthma is associated with COPD and known asthma variants in COPDGene: a genome-wide association study.

Hayden LP, Cho MH, Raby BA, Beaty TH, Silverman EK, Hersh CP; COPDGene Investigators.

Respir Res. 2018 Oct 29;19(1):209. doi: 10.1186/s12931-018-0890-0.

9.
10.

Genetic susceptibility for chronic bronchitis in chronic obstructive pulmonary disease.

Lee JH, Cho MH, Hersh CP, McDonald ML, Crapo JD, Bakke PS, Gulsvik A, Comellas AP, Wendt CH, Lomas DA, Kim V, Silverman EK; COPDGene and ECLIPSE Investigators.

Respir Res. 2014 Sep 21;15:113. doi: 10.1186/s12931-014-0113-2.

11.

Exon sequencing identifies a novel CHRNA3-CHRNA5-CHRNB4 variant that increases the risk for chronic obstructive pulmonary disease.

Zhao Z, Peng F, Zhou Y, Hu G, He H, He F, Zou W, Zhao Z, Li B, Ran P.

Respirology. 2015 Jul;20(5):790-8. doi: 10.1111/resp.12539. Epub 2015 Apr 19.

12.

A genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility loci.

Pillai SG, Ge D, Zhu G, Kong X, Shianna KV, Need AC, Feng S, Hersh CP, Bakke P, Gulsvik A, Ruppert A, Lødrup Carlsen KC, Roses A, Anderson W, Rennard SI, Lomas DA, Silverman EK, Goldstein DB; ICGN Investigators.

PLoS Genet. 2009 Mar;5(3):e1000421. doi: 10.1371/journal.pgen.1000421. Epub 2009 Mar 20.

13.

Exome Array Analysis Identifies a Common Variant in IL27 Associated with Chronic Obstructive Pulmonary Disease.

Hobbs BD, Parker MM, Chen H, Lao T, Hardin M, Qiao D, Hawrylkiewicz I, Sliwinski P, Yim JJ, Kim WJ, Kim DK, Castaldi PJ, Hersh CP, Morrow J, Celli BR, Pinto-Plata VM, Criner GJ, Marchetti N, Bueno R, Agustí A, Make BJ, Crapo JD, Calverley PM, Donner CF, Lomas DA, Wouters EF, Vestbo J, Paré PD, Levy RD, Rennard SI, Zhou X, Laird NM, Lin X, Beaty TH, Silverman EK, Cho MH; NETT Genetics Investigators; ECLIPSE Investigators; COPDGene Investigators; International COPD Genetics Network Investigators.

Am J Respir Crit Care Med. 2016 Jul 1;194(1):48-57. doi: 10.1164/rccm.201510-2053OC.

14.

Gene susceptibility identification in a longitudinal study confirms new loci in the development of chronic obstructive pulmonary disease and influences lung function decline.

Xie J, Wu H, Xu Y, Wu X, Liu X, Shang J, Zhao J, Zhao J, Wang J, Dela Cruz CS, Xiong W, Xu Y.

Respir Res. 2015 Apr 18;16:49. doi: 10.1186/s12931-015-0209-3.

15.

Exome Sequencing Analysis in Severe, Early-Onset Chronic Obstructive Pulmonary Disease.

Qiao D, Lange C, Beaty TH, Crapo JD, Barnes KC, Bamshad M, Hersh CP, Morrow J, Pinto-Plata VM, Marchetti N, Bueno R, Celli BR, Criner GJ, Silverman EK, Cho MH; Lung GO; NHLBI Exome Sequencing Project; COPDGene Investigators.

Am J Respir Crit Care Med. 2016 Jun 15;193(12):1353-63. doi: 10.1164/rccm.201506-1223OC.

16.

Functional polymorphisms of CHRNA3 predict risks of chronic obstructive pulmonary disease and lung cancer in Chinese.

Yang L, Qiu F, Lu X, Huang D, Ma G, Guo Y, Hu M, Zhou Y, Pan M, Tan Y, Zhong H, Ji W, Wei Q, Ran P, Zhong N, Zhou Y, Lu J.

PLoS One. 2012;7(10):e46071. doi: 10.1371/journal.pone.0046071. Epub 2012 Oct 3.

17.

A genome-wide association study of pulmonary function measures in the Framingham Heart Study.

Wilk JB, Chen TH, Gottlieb DJ, Walter RE, Nagle MW, Brandler BJ, Myers RH, Borecki IB, Silverman EK, Weiss ST, O'Connor GT.

PLoS Genet. 2009 Mar;5(3):e1000429. doi: 10.1371/journal.pgen.1000429. Epub 2009 Mar 20.

18.

Association of lung function genes with chronic obstructive pulmonary disease.

Kim WJ, Lim MN, Hong Y, Silverman EK, Lee JH, Jung BH, Ra SW, Choi HS, Jung YJ, Park YB, Park MJ, Lee SW, Lee JS, Oh YM, Lee SD.

Lung. 2014 Aug;192(4):473-80. doi: 10.1007/s00408-014-9579-4. Epub 2014 Apr 16.

PMID:
24737086
19.

Association of HHIP polymorphisms with COPD and COPD-related phenotypes in a Chinese Han population.

Wang B, Zhou H, Yang J, Xiao J, Liang B, Li D, Zhou H, Zeng Q, Fang C, Rao Z, Yu H, Ou X, Feng Y.

Gene. 2013 Nov 15;531(1):101-5. doi: 10.1016/j.gene.2013.08.069. Epub 2013 Aug 30.

PMID:
23994291
20.

Genome-wide association analysis of body mass in chronic obstructive pulmonary disease.

Wan ES, Cho MH, Boutaoui N, Klanderman BJ, Sylvia JS, Ziniti JP, Won S, Lange C, Pillai SG, Anderson WH, Kong X, Lomas DA, Bakke PS, Gulsvik A, Regan EA, Murphy JR, Make BJ, Crapo JD, Wouters EF, Celli BR, Silverman EK, DeMeo DL; Evaluation of Chronic Obstructive Pulmonary Disease Longitudinally to Identify Predictive Surrogate End-Points (ECLIPSE); Norway-Bergen cohort; National Emphysema Treatment Trial; COPD Gene investigators.

Am J Respir Cell Mol Biol. 2011 Aug;45(2):304-10. doi: 10.1165/rcmb.2010-0294OC. Epub 2010 Oct 29.

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