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Caspase-cleaved keratin-18 fragments increase during alcohol withdrawal and predict liver-related death in patients with alcoholic liver disease.

Mueller S, Nahon P, Rausch V, Peccerella T, Silva I, Yagmur E, Straub BK, Lackner C, Seitz HK, Rufat P, Sutton A, Bantel H, Longerich T.

Hepatology. 2017 Jul;66(1):96-107. doi: 10.1002/hep.29099. Epub 2017 May 9.


Nonalcoholic fatty liver disease: biomarkers as diagnostic tools for liver damage assessment in adult patients from Argentina.

Valva P, Rios D, Casciato P, Gadano A, Galdame O, Mullen E, Bertot G, de Matteo E, Preciado MV.

Eur J Gastroenterol Hepatol. 2018 Jun;30(6):637-644. doi: 10.1097/MEG.0000000000001079.


Assessment of non-alcoholic fatty liver disease using serum total cell death and apoptosis markers.

Shen J, Chan HL, Wong GL, Chan AW, Choi PC, Chan HY, Chim AM, Yeung DK, Yu J, Chu WC, Wong VW.

Aliment Pharmacol Ther. 2012 Dec;36(11-12):1057-66. doi: 10.1111/apt.12091. Epub 2012 Oct 16.


The expression of serum M30 and M65 in chronic hepatitis B patients with non-alcoholic fatty liver disease.

Liang J, Han T, Gao YT, Jing L, Ma Z.

Eur Rev Med Pharmacol Sci. 2015 Nov;19(21):4123-9.


Limited utility of plasma M30 in discriminating non-alcoholic steatohepatitis from steatosis--a comparison with routine biochemical markers.

Chan WK, Sthaneshwar P, Nik Mustapha NR, Mahadeva S.

PLoS One. 2014 Sep 3;9(9):e105903. doi: 10.1371/journal.pone.0105903. eCollection 2014.


Prognostic value of M30/M65 for outcome of hepatitis B virus-related acute-on-chronic liver failure.

Zheng SJ, Liu S, Liu M, McCrae MA, Li JF, Han YP, Xu CH, Ren F, Chen Y, Duan ZP.

World J Gastroenterol. 2014 Mar 7;20(9):2403-11. doi: 10.3748/wjg.v20.i9.2403.


(Cleaved) CK18 serum and tissue expression levels differentiate acute HCV reinfection from acute rejection in liver allografts.

Reis H, Wohlschläger J, Hagemann S, Wenzel P, Bechmann LP, Suttorp AC, Schlattjan MJ, Herzer K, Canbay A, Baba HA.

Liver Int. 2015 Mar;35(3):905-13. doi: 10.1111/liv.12572. Epub 2014 May 12.


Serum cytokeratin-18 fragment levels as noninvasive marker of nonalcoholic steatohepatitis in the chilean population.

Arab JP, Hernández-Rocha C, Morales C, Vargas JI, Solís N, Pizarro M, Robles C, Sandoval D, Ponthus S, Benítez C, Barrera F, Soza A, Riquelme A, Arrese M.

Gastroenterol Hepatol. 2017 Jun - Jul;40(6):388-394. doi: 10.1016/j.gastrohep.2017.02.009. Epub 2017 Mar 28. English, Spanish.


Cell Death and Prognosis of Mortality in Alcoholic Hepatitis Patients Using Plasma Keratin-18.

Woolbright BL, Bridges BW, Dunn W, Olson JC, Weinman SA, Jaeschke H.

Gene Expr. 2017 Nov 27;17(4):301-312. doi: 10.3727/105221617X15016197658871. Epub 2017 Aug 3.


Diagnostic and prognostic significance of cell death and macrophage activation markers in patients with hepatocellular carcinoma.

Waidmann O, Köberle V, Bettinger D, Trojan J, Zeuzem S, Schultheiß M, Kronenberger B, Piiper A.

J Hepatol. 2013 Oct;59(4):769-79. doi: 10.1016/j.jhep.2013.06.008. Epub 2013 Jun 17.


The prognostic significance of the increase in the serum M30 and M65 values after chemotherapy and relationship between these values and clinicopathological factors in patients with advanced gastric cancer.

Bilici A, Ustaalioglu BB, Ercan S, Seker M, Yilmaz BE, Orcun A, Gumus M.

Tumour Biol. 2012 Dec;33(6):2201-8. doi: 10.1007/s13277-012-0481-5. Epub 2012 Aug 14.


Soluble forms of extracellular cytokeratin 18 may differentiate simple steatosis from nonalcoholic steatohepatitis.

Yilmaz Y, Dolar E, Ulukaya E, Akgoz S, Keskin M, Kiyici M, Aker S, Yilmaztepe A, Gurel S, Gulten M, Nak SG.

World J Gastroenterol. 2007 Feb 14;13(6):837-44.


Hepatic sonic hedgehog protein expression measured by computer assisted morphometry significantly correlates with features of non-alcoholic steatohepatitis.

Estep M, Mehta R, Bratthauer G, Alaparthi L, Monge F, Ali S, Abdelatif D, Younoszai Z, Stepanova M, Goodman ZD, Younossi ZM.

BMC Gastroenterol. 2019 Feb 11;19(1):27. doi: 10.1186/s12876-019-0951-y.


Serum apoptosis markers related to liver damage in chronic hepatitis C: sFas as a marker of advanced fibrosis in children and adults while M30 of severe steatosis only in children.

Valva P, Casciato P, Lezama C, Galoppo M, Gadano A, Galdame O, Galoppo MC, Mullen E, De Matteo E, Preciado MV.

PLoS One. 2013;8(1):e53519. doi: 10.1371/journal.pone.0053519. Epub 2013 Jan 11.


Diagnostic value of serum M30 and M65 in patients with nasopharyngeal carcinoma.

Sen F, Yildiz I, Odabas H, Tambas M, Kilic L, Karadeniz A, Altun M, Ekenel M, Serilmez M, Duranyildiz D, Bavbek S, Basaran M.

Tumour Biol. 2015 Feb;36(2):1039-44. doi: 10.1007/s13277-014-2708-0. Epub 2014 Oct 18.


Cell death biomarker M65 is a useful indicator of liver inflammation and fibrosis in chronic hepatitis B: A cross-sectional study of diagnostic accuracy.

Wei X, Wei H, Lin W, Hu Z, Zhang J.

Medicine (Baltimore). 2017 May;96(20):e6807. doi: 10.1097/MD.0000000000006807.


Correlation between serum cytokeratin-18 and the progression or regression of non-alcoholic fatty liver disease.

Kawanaka M, Nishino K, Nakamura J, Urata N, Oka T, Goto D, Suehiro M, Kawamoto H, Yamada G.

Ann Hepatol. 2015 Nov-Dec;14(6):837-44. doi: 10.5604/16652681.1171767.


Is there any impact of plasma M30 and M65 levels on progression-free survival of patients with advanced gastric cancer?

Bilici A, Ustaalioglu BB, Ercan S, Orcun A, Seker M, Salepci T, Gumus M.

Cancer Chemother Pharmacol. 2011 Aug;68(2):309-16. doi: 10.1007/s00280-010-1480-0. Epub 2010 Oct 22.


Prospective biopsy-controlled evaluation of cell death biomarkers for prediction of liver fibrosis and nonalcoholic steatohepatitis.

Joka D, Wahl K, Moeller S, Schlue J, Vaske B, Bahr MJ, Manns MP, Schulze-Osthoff K, Bantel H.

Hepatology. 2012 Feb;55(2):455-64. doi: 10.1002/hep.24734. Epub 2011 Nov 29.


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