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Items: 1 to 20 of 93


Synthetic lethal mutations in the cyclin A interface of human cytomegalovirus.

Weisbach H, Schablowsky C, Vetter B, Gruska I, Hagemeier C, Wiebusch L.

PLoS Pathog. 2017 Jan 27;13(1):e1006193. doi: 10.1371/journal.ppat.1006193. eCollection 2017 Jan.


Human cytomegalovirus tegument protein pp150 acts as a cyclin A2-CDK-dependent sensor of the host cell cycle and differentiation state.

Bogdanow B, Weisbach H, von Einem J, Straschewski S, Voigt S, Winkler M, Hagemeier C, Wiebusch L.

Proc Natl Acad Sci U S A. 2013 Oct 22;110(43):17510-5. doi: 10.1073/pnas.1312235110. Epub 2013 Oct 7.


The smallest capsid protein mediates binding of the essential tegument protein pp150 to stabilize DNA-containing capsids in human cytomegalovirus.

Dai X, Yu X, Gong H, Jiang X, Abenes G, Liu H, Shivakoti S, Britt WJ, Zhu H, Liu F, Zhou ZH.

PLoS Pathog. 2013 Aug;9(8):e1003525. doi: 10.1371/journal.ppat.1003525. Epub 2013 Aug 15.


Highly acidic C-terminal region of cytomegalovirus pUL96 determines its functions during virus maturation independently of a direct pp150 interaction.

Brechtel TM, Mocarski ES, Tandon R.

J Virol. 2014 Apr;88(8):4493-503. doi: 10.1128/JVI.03784-13. Epub 2014 Feb 5.


PUL21a-Cyclin A2 interaction is required to protect human cytomegalovirus-infected cells from the deleterious consequences of mitotic entry.

Eifler M, Uecker R, Weisbach H, Bogdanow B, Richter E, König L, Vetter B, Lenac-Rovis T, Jonjic S, Neitzel H, Hagemeier C, Wiebusch L.

PLoS Pathog. 2014 Nov 13;10(10):e1004514. doi: 10.1371/journal.ppat.1004514. eCollection 2014 Oct.


Nuclear localization of the human cytomegalovirus tegument protein pp150 (ppUL32).

Hensel G, Meyer H, Gärtner S, Brand G, Kern HF.

J Gen Virol. 1995 Jul;76 ( Pt 7):1591-601.


Cyclin A degradation by primate cytomegalovirus protein pUL21a counters its innate restriction of virus replication.

Caffarelli N, Fehr AR, Yu D.

PLoS Pathog. 2013;9(12):e1003825. doi: 10.1371/journal.ppat.1003825. Epub 2013 Dec 26.


Atomic structures and deletion mutant reveal different capsid-binding patterns and functional significance of tegument protein pp150 in murine and human cytomegaloviruses with implications for therapeutic development.

Liu W, Dai X, Jih J, Chan K, Trang P, Yu X, Balogun R, Mei Y, Liu F, Zhou ZH.

PLoS Pathog. 2019 Feb 19;15(2):e1007615. doi: 10.1371/journal.ppat.1007615. eCollection 2019 Feb.


A role for the small GTPase Rab6 in assembly of human cytomegalovirus.

Indran SV, Britt WJ.

J Virol. 2011 May;85(10):5213-9. doi: 10.1128/JVI.02605-10. Epub 2011 Mar 16.


Regulatory Interaction between the Cellular Restriction Factor IFI16 and Viral pp65 (pUL83) Modulates Viral Gene Expression and IFI16 Protein Stability.

Biolatti M, Dell'Oste V, Pautasso S, von Einem J, Marschall M, Plachter B, Gariglio M, De Andrea M, Landolfo S.

J Virol. 2016 Aug 26;90(18):8238-50. doi: 10.1128/JVI.00923-16. Print 2016 Sep 15.


Innate nuclear sensor IFI16 translocates into the cytoplasm during the early stage of in vitro human cytomegalovirus infection and is entrapped in the egressing virions during the late stage.

Dell'Oste V, Gatti D, Gugliesi F, De Andrea M, Bawadekar M, Lo Cigno I, Biolatti M, Vallino M, Marschall M, Gariglio M, Landolfo S.

J Virol. 2014 Jun;88(12):6970-82. doi: 10.1128/JVI.00384-14. Epub 2014 Apr 2.


Human cytomegalovirus riding the cell cycle.

Spector DH.

Med Microbiol Immunol. 2015 Jun;204(3):409-19. doi: 10.1007/s00430-015-0396-z. Epub 2015 Mar 17. Review.


Bicaudal D1-dependent trafficking of human cytomegalovirus tegument protein pp150 in virus-infected cells.

Indran SV, Ballestas ME, Britt WJ.

J Virol. 2010 Apr;84(7):3162-77. doi: 10.1128/JVI.01776-09. Epub 2010 Jan 20.


Cyclin-dependent kinase activity controls the onset of the HCMV lytic cycle.

Zydek M, Hagemeier C, Wiebusch L.

PLoS Pathog. 2010 Sep 9;6(9):e1001096. doi: 10.1371/journal.ppat.1001096.


Establishment and validation of an enzyme-linked immunosorbent assay for IgG antibody against cytomegalovirus based on pp150 antigen.

Xi H, Jinjie L, Shengxiang G, Tingdong L, Han W, Xiaoyi G, Tong-Ming F, Jun Z.

J Virol Methods. 2017 Feb;240:21-25. doi: 10.1016/j.jviromet.2016.11.001. Epub 2016 Nov 4.


Human cytomegalovirus protein pUL117 targets the mini-chromosome maintenance complex and suppresses cellular DNA synthesis.

Qian Z, Leung-Pineda V, Xuan B, Piwnica-Worms H, Yu D.

PLoS Pathog. 2010 Mar 19;6(3):e1000814. doi: 10.1371/journal.ppat.1000814.


The Cellular Proteins Grb2 and DDX3 Are Increased upon Human Cytomegalovirus Infection and Act in a Proviral Fashion.

Cavignac Y, Lieber D, Laib Sampaio K, Madlung J, Lamkemeyer T, Jahn G, Nordheim A, Sinzger C.

PLoS One. 2015 Jun 29;10(6):e0131614. doi: 10.1371/journal.pone.0131614. eCollection 2015.


Inhibition of human cytomegalovirus immediate-early gene expression by cyclin A2-dependent kinase activity.

Oduro JD, Uecker R, Hagemeier C, Wiebusch L.

J Virol. 2012 Sep;86(17):9369-83. doi: 10.1128/JVI.07181-11. Epub 2012 Jun 20.

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