Similar articles for PMID: 28098219

Year	Number of Results
1994	1
1999	1
2003	1
2006	1
2008	2
2009	4
2010	2
2011	1
2012	3
2013	2
2014	10
2015	15
2016	15
2017	21
2018	14
2019	11
2020	10
2021	5
2022	5
2023	1
2024	0

1

Combined LRRK2 mutation, aging and chronic low dose oral rotenone as a model of Parkinson's disease.

Liu HF, Ho PW, Leung GC, Lam CS, Pang SY, Li L, Kung MH, Ramsden DB, Ho SL. Liu HF, et al. Sci Rep. 2017 Jan 18;7:40887. doi: 10.1038/srep40887. Sci Rep. 2017. PMID: 28098219 Free PMC article.

2

Dopamine D2 receptor-mediated neuroprotection in a G2019S Lrrk2 genetic model of Parkinson's disease.

Tozzi A, Tantucci M, Marchi S, Mazzocchetti P, Morari M, Pinton P, Mancini A, Calabresi P. Tozzi A, et al. Cell Death Dis. 2018 Feb 12;9(2):204. doi: 10.1038/s41419-017-0221-2. Cell Death Dis. 2018. PMID: 29434188 Free PMC article.

3

Age-dependent dopamine transporter dysfunction and Serine129 phospho-α-synuclein overload in G2019S LRRK2 mice.

Longo F, Mercatelli D, Novello S, Arcuri L, Brugnoli A, Vincenzi F, Russo I, Berti G, Mabrouk OS, Kennedy RT, Shimshek DR, Varani K, Bubacco L, Greggio E, Morari M. Longo F, et al. Acta Neuropathol Commun. 2017 Mar 14;5(1):22. doi: 10.1186/s40478-017-0426-8. Acta Neuropathol Commun. 2017. PMID: 28292328 Free PMC article.

4

LRRK2 BAC transgenic rats develop progressive, L-DOPA-responsive motor impairment, and deficits in dopamine circuit function.

Sloan M, Alegre-Abarrategui J, Potgieter D, Kaufmann AK, Exley R, Deltheil T, Threlfell S, Connor-Robson N, Brimblecombe K, Wallings R, Cioroch M, Bannerman DM, Bolam JP, Magill PJ, Cragg SJ, Dodson PD, Wade-Martins R. Sloan M, et al. Hum Mol Genet. 2016 Mar 1;25(5):951-63. doi: 10.1093/hmg/ddv628. Epub 2016 Jan 6. Hum Mol Genet. 2016. PMID: 26744332 Free PMC article.

5

In vivo overexpression of synaptogyrin-3 promotes striatal synaptic dopamine uptake in LRRK2^R1441G mutant mouse model of Parkinson's disease.

Ho PW, Li L, Liu HF, Choi ZY, Chang EES, Pang SY, Malki Y, Leung CT, Kung MH, Ramsden DB, Ho SL. Ho PW, et al. Brain Behav. 2023 Feb;13(2):e2886. doi: 10.1002/brb3.2886. Epub 2023 Jan 9. Brain Behav. 2023. PMID: 36624932 Free PMC article.

6

Age-dependent accumulation of oligomeric SNCA/α-synuclein from impaired degradation in mutant LRRK2 knockin mouse model of Parkinson disease: role for therapeutic activation of chaperone-mediated autophagy (CMA).

Ho PW, Leung CT, Liu H, Pang SY, Lam CS, Xian J, Li L, Kung MH, Ramsden DB, Ho SL. Ho PW, et al. Autophagy. 2020 Feb;16(2):347-370. doi: 10.1080/15548627.2019.1603545. Epub 2019 Apr 14. Autophagy. 2020. PMID: 30983487 Free PMC article.

7

Parkinson's disease-related Leucine-rich repeat kinase 2 modulates nuclear morphology and genomic stability in striatal projection neurons during aging.

Chen X, Xie C, Tian W, Sun L, Zheng W, Hawes S, Chang L, Kung J, Ding J, Chen S, Le W, Cai H. Chen X, et al. Mol Neurodegener. 2020 Feb 19;15(1):12. doi: 10.1186/s13024-020-00360-0. Mol Neurodegener. 2020. PMID: 32075681 Free PMC article.

8

Selective expression of Parkinson's disease-related Leucine-rich repeat kinase 2 G2019S missense mutation in midbrain dopaminergic neurons impairs dopamine release and dopaminergic gene expression.

Liu G, Sgobio C, Gu X, Sun L, Lin X, Yu J, Parisiadou L, Xie C, Sastry N, Ding J, Lohr KM, Miller GW, Mateo Y, Lovinger DM, Cai H. Liu G, et al. Hum Mol Genet. 2015 Sep 15;24(18):5299-312. doi: 10.1093/hmg/ddv249. Epub 2015 Jun 29. Hum Mol Genet. 2015. PMID: 26123485 Free PMC article.

9

Leucine-rich repeat kinase 2 (LRRK2) inhibitors differentially modulate glutamate release and Serine935 LRRK2 phosphorylation in striatal and cerebrocortical synaptosomes.

Mercatelli D, Bolognesi P, Frassineti M, Pisanò CA, Longo F, Shimshek DR, Morari M. Mercatelli D, et al. Pharmacol Res Perspect. 2019 May 27;7(3):e00484. doi: 10.1002/prp2.484. eCollection 2019 Jun. Pharmacol Res Perspect. 2019. PMID: 31149340 Free PMC article.

10

Mitochondrial Calcium Dysregulation Contributes to Dendrite Degeneration Mediated by PD/LBD-Associated LRRK2 Mutants.

Verma M, Callio J, Otero PA, Sekler I, Wills ZP, Chu CT. Verma M, et al. J Neurosci. 2017 Nov 15;37(46):11151-11165. doi: 10.1523/JNEUROSCI.3791-16.2017. Epub 2017 Oct 16. J Neurosci. 2017. PMID: 29038245 Free PMC article.

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