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Items: 1 to 20 of 95

1.

5-Flurouracil disrupts nuclear export and nuclear pore permeability in a calcium dependent manner.

Higby KJ, Bischak MM, Campbell CA, Anderson RG, Broskin SA, Foltz LE, Koper JA, Nickle AC, Resendes KK.

Apoptosis. 2017 Mar;22(3):393-405. doi: 10.1007/s10495-016-1338-y.

PMID:
28000054
2.

Calcium-dependent regulation of NEMO nuclear export in response to genotoxic stimuli.

Berchtold CM, Wu ZH, Huang TT, Miyamoto S.

Mol Cell Biol. 2007 Jan;27(2):497-509. Epub 2006 Oct 30.

3.

Irinotecan/5-fluorouracil combination induces alterations in mitochondrial membrane potential and caspases on colon cancer cell lines.

Grivicich I, Regner A, da Rocha AB, Grass LB, Alves PA, Kayser GB, Schwartsmann G, Henriques JA.

Oncol Res. 2005;15(7-8):385-92.

PMID:
16491956
4.

Caspases mediate nucleoporin cleavage, but not early redistribution of nuclear transport factors and modulation of nuclear permeability in apoptosis.

Ferrando-May E, Cordes V, Biller-Ckovric I, Mirkovic J, Görlich D, Nicotera P.

Cell Death Differ. 2001 May;8(5):495-505.

5.

Camptothecin induces nuclear export of prohibitin preferentially in transformed cells through a CRM-1-dependent mechanism.

Rastogi S, Joshi B, Fusaro G, Chellappan S.

J Biol Chem. 2006 Feb 3;281(5):2951-9. Epub 2005 Nov 30.

6.

5-Fluorouracil signaling through a calcium-calmodulin-dependent pathway is required for p53 activation and apoptosis in colon carcinoma cells.

Can G, Akpinar B, Baran Y, Zhivotovsky B, Olsson M.

Oncogene. 2013 Sep 19;32(38):4529-38. doi: 10.1038/onc.2012.467. Epub 2012 Oct 29.

PMID:
23108402
7.

The Cellular Distribution of RanGAP1 Is Regulated by CRM1-Mediated Nuclear Export in Mammalian Cells.

Cha K, Sen P, Raghunayakula S, Zhang XD.

PLoS One. 2015 Oct 27;10(10):e0141309. doi: 10.1371/journal.pone.0141309. eCollection 2015.

8.

Inhibition of Fas expression by RNAi modulates 5-fluorouracil-induced apoptosis in HCT116 cells expressing wild-type p53.

Borralho PM, Moreira da Silva IB, Aranha MM, Albuquerque C, Nobre Leitão C, Steer CJ, Rodrigues CM.

Biochim Biophys Acta. 2007 Jan;1772(1):40-7. Epub 2006 Sep 16.

9.

Resveratrol displays converse dose-related effects on 5-fluorouracil-evoked colon cancer cell apoptosis: the roles of caspase-6 and p53.

Chan JY, Phoo MS, Clement MV, Pervaiz S, Lee SC.

Cancer Biol Ther. 2008 Aug;7(8):1305-12. Epub 2008 Aug 16.

PMID:
18497562
10.

5-Fluorouracil-induced RNA stress engages a TRAIL-DISC-dependent apoptosis axis facilitated by p53.

Akpinar B, Bracht EV, Reijnders D, Safarikova B, Jelinkova I, Grandien A, Vaculova AH, Zhivotovsky B, Olsson M.

Oncotarget. 2015 Dec 22;6(41):43679-97. doi: 10.18632/oncotarget.6030. Erratum in: Oncotarget. 2016 May 10;7(19):28761-2. Oncotarget. 2016 Nov 1;7(44):72380.

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13.

Characterization of p53 wild-type and null isogenic colorectal cancer cell lines resistant to 5-fluorouracil, oxaliplatin, and irinotecan.

Boyer J, McLean EG, Aroori S, Wilson P, McCulla A, Carey PD, Longley DB, Johnston PG.

Clin Cancer Res. 2004 Mar 15;10(6):2158-67.

14.

Thymidylate synthase inhibition induces p53-dependent and p53-independent apoptotic responses in human urinary bladder cancer cells.

Stravopodis DJ, Karkoulis PK, Konstantakou EG, Melachroinou S, Thanasopoulou A, Aravantinos G, Margaritis LH, Anastasiadou E, Voutsinas GE.

J Cancer Res Clin Oncol. 2011 Feb;137(2):359-74. doi: 10.1007/s00432-010-0891-y. Epub 2010 Apr 28.

PMID:
20425122
15.
16.

Importin-β modulates the permeability of the nuclear pore complex in a Ran-dependent manner.

Lowe AR, Tang JH, Yassif J, Graf M, Huang WY, Groves JT, Weis K, Liphardt JT.

Elife. 2015 Mar 6;4. doi: 10.7554/eLife.04052.

17.

A role for RanBP1 in the release of CRM1 from the nuclear pore complex in a terminal step of nuclear export.

Kehlenbach RH, Dickmanns A, Kehlenbach A, Guan T, Gerace L.

J Cell Biol. 1999 May 17;145(4):645-57.

18.

Nuclear-cytoplasmic trafficking of NTF2, the nuclear import receptor for the RanGTPase, is subjected to regulation.

Chafe SC, Pierce JB, Mangroo D.

PLoS One. 2012;7(8):e42501. doi: 10.1371/journal.pone.0042501. Epub 2012 Aug 3.

19.

Inducible nuclear factor-kappaB activation contributes to chemotherapy resistance in gastric cancer.

Camp ER, Li J, Minnich DJ, Brank A, Moldawer LL, MacKay SL, Hochwald SN.

J Am Coll Surg. 2004 Aug;199(2):249-58.

PMID:
15275881
20.

Topotecan-triggered degradation of topoisomerase I is p53-dependent and impacts cell survival.

Tomicic MT, Christmann M, Kaina B.

Cancer Res. 2005 Oct 1;65(19):8920-6.

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