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Items: 1 to 20 of 101


The genomic landscape of rapid repeated evolutionary adaptation to toxic pollution in wild fish.

Reid NM, Proestou DA, Clark BW, Warren WC, Colbourne JK, Shaw JR, Karchner SI, Hahn ME, Nacci D, Oleksiak MF, Crawford DL, Whitehead A.

Science. 2016 Dec 9;354(6317):1305-1308.


Genetic basis for rapidly evolved tolerance in the wild: adaptation to toxic pollutants by an estuarine fish species.

Nacci D, Proestou D, Champlin D, Martinson J, Waits ER.

Mol Ecol. 2016 Nov;25(21):5467-5482. doi: 10.1111/mec.13848. Epub 2016 Oct 20.


Common mechanism underlies repeated evolution of extreme pollution tolerance.

Whitehead A, Pilcher W, Champlin D, Nacci D.

Proc Biol Sci. 2012 Feb 7;279(1728):427-33. doi: 10.1098/rspb.2011.0847. Epub 2011 Jul 6.


Targeted approach to identify genetic loci associated with evolved dioxin tolerance in Atlantic killifish (Fundulus heteroclitus).

Proestou DA, Flight P, Champlin D, Nacci D.

BMC Evol Biol. 2014 Jan 14;14(1):7. doi: 10.1186/1471-2148-14-7.


Comparative transcriptomics implicates mechanisms of evolved pollution tolerance in a killifish population.

Whitehead A, Triant DA, Champlin D, Nacci D.

Mol Ecol. 2010 Dec;19(23):5186-203. doi: 10.1111/j.1365-294X.2010.04829.x. Epub 2010 Sep 27.


Genetic variation at aryl hydrocarbon receptor (AHR) loci in populations of Atlantic killifish (Fundulus heteroclitus) inhabiting polluted and reference habitats.

Reitzel AM, Karchner SI, Franks DG, Evans BR, Nacci D, Champlin D, Vieira VM, Hahn ME.

BMC Evol Biol. 2014 Jan 14;14:6. doi: 10.1186/1471-2148-14-6.


Role of DNA methylation of AHR1 and AHR2 promoters in differential sensitivity to PCBs in Atlantic Killifish, Fundulus heteroclitus.

Aluru N, Karchner SI, Hahn ME.

Aquat Toxicol. 2011 Jan 17;101(1):288-94. doi: 10.1016/j.aquatox.2010.10.010. Epub 2010 Oct 30.


Functional genomics of physiological plasticity and local adaptation in killifish.

Whitehead A, Galvez F, Zhang S, Williams LM, Oleksiak MF.

J Hered. 2011 Sep-Oct;102(5):499-511. doi: 10.1093/jhered/esq077. Epub 2010 Jun 25.


Genome-wide scan reveals signatures of selection related to pollution adaptation in non-model estuarine Atlantic killifish (Fundulus heteroclitus).

Osterberg JS, Cammen KM, Schultz TF, Clark BW, Di Giulio RT.

Aquat Toxicol. 2018 Jul;200:73-82. doi: 10.1016/j.aquatox.2018.04.017. Epub 2018 Apr 25.


When evolution is the solution to pollution: Key principles, and lessons from rapid repeated adaptation of killifish (Fundulus heteroclitus) populations.

Whitehead A, Clark BW, Reid NM, Hahn ME, Nacci D.

Evol Appl. 2017 Apr 26;10(8):762-783. doi: 10.1111/eva.12470. eCollection 2017 Sep. Review.


Characterization of the recalcitrant CYP1 phenotype found in Atlantic killifish (Fundulus heteroclitus) inhabiting a Superfund site on the Elizabeth River, VA.

Wills LP, Matson CW, Landon CD, Di Giulio RT.

Aquat Toxicol. 2010 Aug 1;99(1):33-41. doi: 10.1016/j.aquatox.2010.03.015. Epub 2010 Apr 14.


Population genomics of rapid evolution in natural populations: polygenic selection in response to power station thermal effluents.

Dayan DI, Du X, Baris TZ, Wagner DN, Crawford DL, Oleksiak MF.

BMC Evol Biol. 2019 Feb 26;19(1):61. doi: 10.1186/s12862-019-1392-5.


Expression and inducibility of aryl hydrocarbon receptor pathway genes in wild-caught killifish (Fundulus heteroclitus) with different contaminant-exposure histories.

Meyer JN, Wassenberg DM, Karchner SI, Hahn ME, Di Giulio RT.

Environ Toxicol Chem. 2003 Oct;22(10):2337-43.


Targeted mutagenesis of aryl hydrocarbon receptor 2a and 2b genes in Atlantic killifish (Fundulus heteroclitus).

Aluru N, Karchner SI, Franks DG, Nacci D, Champlin D, Hahn ME.

Aquat Toxicol. 2015 Jan;158:192-201. doi: 10.1016/j.aquatox.2014.11.016. Epub 2014 Nov 26.


Distinguishing Among Modes of Convergent Adaptation Using Population Genomic Data.

Lee KM, Coop G.

Genetics. 2017 Dec;207(4):1591-1619. doi: 10.1534/genetics.117.300417. Epub 2017 Oct 18.


Common functional targets of adaptive micro- and macro-evolutionary divergence in killifish.

Whitehead A, Zhang S, Roach JL, Galvez F.

Mol Ecol. 2013 Jul;22(14):3780-96. doi: 10.1111/mec.12316.


Altered lipid homeostasis in a PCB-resistant Atlantic killifish (Fundulus heteroclitus) population from New Bedford Harbor, MA, U.S.A.

Crawford KA, Clark BW, Heiger-Bernays WJ, Karchner SI, Claus Henn BG, Griffith KN, Howes BL, Schlezinger DR, Hahn ME, Nacci DE, Schlezinger JJ.

Aquat Toxicol. 2019 May;210:30-43. doi: 10.1016/j.aquatox.2019.02.011. Epub 2019 Feb 18.


Embryonic cardiotoxicity of weak aryl hydrocarbon receptor agonists and CYP1A inhibitor fluoranthene in the Atlantic killifish (Fundulus heteroclitus).

Brown DR, Clark BW, Garner LV, Di Giulio RT.

Comp Biochem Physiol C Toxicol Pharmacol. 2016 Oct;188:45-51. doi: 10.1016/j.cbpc.2016.05.005. Epub 2016 May 20.


Resistance to teratogenesis by F1 and F2 embryos of PAH-adapted Fundulus heteroclitus is strongly inherited despite reduced recalcitrance of the AHR pathway.

Clark BW, Bone AJ, Di Giulio RT.

Environ Sci Pollut Res Int. 2014 Dec;21(24):13898-908. doi: 10.1007/s11356-013-2446-7. Epub 2013 Dec 28.


Resistance to polycyclic aromatic hydrocarbon toxicity and associated bioenergetic consequences in a population of Fundulus heteroclitus.

Lindberg CD, Jayasundara N, Kozal JS, Leuthner TC, Di Giulio RT.

Ecotoxicology. 2017 Apr;26(3):435-448. doi: 10.1007/s10646-017-1775-6. Epub 2017 Feb 17.

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