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Items: 1 to 20 of 116


The role of break-induced replication in large-scale expansions of (CAG)n/(CTG)n repeats.

Kim JC, Harris ST, Dinter T, Shah KA, Mirkin SM.

Nat Struct Mol Biol. 2017 Jan;24(1):55-60. doi: 10.1038/nsmb.3334. Epub 2016 Dec 5.


Double-strand break repair pathways protect against CAG/CTG repeat expansions, contractions and repeat-mediated chromosomal fragility in Saccharomyces cerevisiae.

Sundararajan R, Gellon L, Zunder RM, Freudenreich CH.

Genetics. 2010 Jan;184(1):65-77. doi: 10.1534/genetics.109.111039. Epub 2009 Nov 9. Erratum in: Genetics. 2011 Apr;187(4):1245.


Replication stalling and heteroduplex formation within CAG/CTG trinucleotide repeats by mismatch repair.

Viterbo D, Michoud G, Mosbach V, Dujon B, Richard GF.

DNA Repair (Amst). 2016 Jun;42:94-106. doi: 10.1016/j.dnarep.2016.03.002. Epub 2016 Mar 16.


Orientation-dependent and sequence-specific expansions of CTG/CAG trinucleotide repeats in Saccharomyces cerevisiae.

Miret JJ, Pessoa-Brandão L, Lahue RS.

Proc Natl Acad Sci U S A. 1998 Oct 13;95(21):12438-43.


TALEN-Induced Double-Strand Break Repair of CTG Trinucleotide Repeats.

Mosbach V, Poggi L, Viterbo D, Charpentier M, Richard GF.

Cell Rep. 2018 Feb 20;22(8):2146-2159. doi: 10.1016/j.celrep.2018.01.083.


Postreplication repair inhibits CAG.CTG repeat expansions in Saccharomyces cerevisiae.

Daee DL, Mertz T, Lahue RS.

Mol Cell Biol. 2007 Jan;27(1):102-10. Epub 2006 Oct 23.


Replication and expansion of trinucleotide repeats in yeast.

Pelletier R, Krasilnikova MM, Samadashwily GM, Lahue R, Mirkin SM.

Mol Cell Biol. 2003 Feb;23(4):1349-57.


Double-strand break repair can lead to high frequencies of deletions within short CAG/CTG trinucleotide repeats.

Richard GF, Dujon B, Haber JE.

Mol Gen Genet. 1999 Jun;261(4-5):871-82.


The Saccharomyces cerevisiae Mre11-Rad50-Xrs2 complex promotes trinucleotide repeat expansions independently of homologous recombination.

Ye Y, Kirkham-McCarthy L, Lahue RS.

DNA Repair (Amst). 2016 Jul;43:1-8. doi: 10.1016/j.dnarep.2016.04.012. Epub 2016 May 2.


Absence of MutSβ leads to the formation of slipped-DNA for CTG/CAG contractions at primate replication forks.

Slean MM, Panigrahi GB, Castel AL, Pearson AB, Tomkinson AE, Pearson CE.

DNA Repair (Amst). 2016 Jun;42:107-18. doi: 10.1016/j.dnarep.2016.04.002. Epub 2016 Apr 16.


Recombination-induced CAG trinucleotide repeat expansions in yeast involve the MRE11-RAD50-XRS2 complex.

Richard GF, Goellner GM, McMurray CT, Haber JE.

EMBO J. 2000 May 15;19(10):2381-90.


Coupling transcriptional state to large-scale repeat expansions in yeast.

Shah KA, McGinty RJ, Egorova VI, Mirkin SM.

Cell Rep. 2014 Dec 11;9(5):1594-1602. doi: 10.1016/j.celrep.2014.10.048. Epub 2014 Nov 20.


Expanded CAG/CTG repeat DNA induces a checkpoint response that impacts cell proliferation in Saccharomyces cerevisiae.

Sundararajan R, Freudenreich CH.

PLoS Genet. 2011 Mar;7(3):e1001339. doi: 10.1371/journal.pgen.1001339. Epub 2011 Mar 17.


Cytosine deamination and base excision repair cause R-loop-induced CAG repeat fragility and instability in Saccharomyces cerevisiae.

Su XA, Freudenreich CH.

Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):E8392-E8401. doi: 10.1073/pnas.1711283114. Epub 2017 Sep 18.


In vitro (CTG)*(CAG) expansions and deletions by human cell extracts.

Panigrahi GB, Cleary JD, Pearson CE.

J Biol Chem. 2002 Apr 19;277(16):13926-34. Epub 2002 Feb 6.


MutSβ promotes trinucleotide repeat expansion by recruiting DNA polymerase β to nascent (CAG)n or (CTG)n hairpins for error-prone DNA synthesis.

Guo J, Gu L, Leffak M, Li GM.

Cell Res. 2016 Jul;26(7):775-86. doi: 10.1038/cr.2016.66. Epub 2016 Jun 3.


Replication restart: a pathway for (CTG).(CAG) repeat deletion in Escherichia coli.

Kim SH, Pytlos MJ, Sinden RR.

Mutat Res. 2006 Mar 20;595(1-2):5-22.


Rev1 enhances CAG.CTG repeat stability in Saccharomyces cerevisiae.

Collins NS, Bhattacharyya S, Lahue RS.

DNA Repair (Amst). 2007 Jan 4;6(1):38-44. Epub 2006 Sep 15.


Mutations in yeast replication proteins that increase CAG/CTG expansions also increase repeat fragility.

Callahan JL, Andrews KJ, Zakian VA, Freudenreich CH.

Mol Cell Biol. 2003 Nov;23(21):7849-60.

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