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Items: 1 to 20 of 121

1.

K63-Linked Ubiquitination Targets Toxoplasma gondii for Endo-lysosomal Destruction in IFNγ-Stimulated Human Cells.

Clough B, Wright JD, Pereira PM, Hirst EM, Johnston AC, Henriques R, Frickel EM.

PLoS Pathog. 2016 Nov 22;12(11):e1006027. doi: 10.1371/journal.ppat.1006027. eCollection 2016 Nov.

2.

A Noncanonical Autophagy Pathway Restricts Toxoplasma gondii Growth in a Strain-Specific Manner in IFN-γ-Activated Human Cells.

Selleck EM, Orchard RC, Lassen KG, Beatty WL, Xavier RJ, Levine B, Virgin HW, Sibley LD.

MBio. 2015 Sep 8;6(5):e01157-15. doi: 10.1128/mBio.01157-15.

3.

Autophagy in immunity against Toxoplasma gondii.

Subauste CS.

Curr Top Microbiol Immunol. 2009;335:251-65. doi: 10.1007/978-3-642-00302-8_12. Review.

PMID:
19802569
4.

CD40, autophagy and Toxoplasma gondii.

Subauste CS.

Mem Inst Oswaldo Cruz. 2009 Mar;104(2):267-72.

5.

Exposing Toxoplasma gondii hiding inside the vacuole: a role for GBPs, autophagy and host cell death.

Saeij JP, Frickel EM.

Curr Opin Microbiol. 2017 Dec;40:72-80. doi: 10.1016/j.mib.2017.10.021. Epub 2017 Nov 12. Review.

6.

Disruption of the Toxoplasma gondii parasitophorous vacuole by IFNgamma-inducible immunity-related GTPases (IRG proteins) triggers necrotic cell death.

Zhao YO, Khaminets A, Hunn JP, Howard JC.

PLoS Pathog. 2009 Feb;5(2):e1000288. doi: 10.1371/journal.ppat.1000288. Epub 2009 Feb 6.

7.

The parasitophorous vacuole membrane of Toxoplasma gondii is targeted for disruption by ubiquitin-like conjugation systems of autophagy.

Choi J, Park S, Biering SB, Selleck E, Liu CY, Zhang X, Fujita N, Saitoh T, Akira S, Yoshimori T, Sibley LD, Hwang S, Virgin HW.

Immunity. 2014 Jun 19;40(6):924-35. doi: 10.1016/j.immuni.2014.05.006. Epub 2014 Jun 12.

8.

Forward genetics screens using macrophages to identify Toxoplasma gondii genes important for resistance to IFN-γ-dependent cell autonomous immunity.

Walwyn O, Skariah S, Lynch B, Kim N, Ueda Y, Vohora N, Choe J, Mordue DG.

J Vis Exp. 2015 Mar 12;(97):52556. doi: 10.3791/52556.

9.

TRIM21 is critical for survival of Toxoplasma gondii infection and localises to GBP-positive parasite vacuoles.

Foltz C, Napolitano A, Khan R, Clough B, Hirst EM, Frickel EM.

Sci Rep. 2017 Jul 12;7(1):5209. doi: 10.1038/s41598-017-05487-7.

10.

Guanylate-binding protein 1 (GBP1) contributes to the immunity of human mesenchymal stromal cells against Toxoplasma gondii.

Qin A, Lai DH, Liu Q, Huang W, Wu YP, Chen X, Yan S, Xia H, Hide G, Lun ZR, Ayala FJ, Xiang AP.

Proc Natl Acad Sci U S A. 2017 Feb 7;114(6):1365-1370. doi: 10.1073/pnas.1619665114. Epub 2017 Jan 25.

11.

Vacuolar and plasma membrane stripping and autophagic elimination of Toxoplasma gondii in primed effector macrophages.

Ling YM, Shaw MH, Ayala C, Coppens I, Taylor GA, Ferguson DJ, Yap GS.

J Exp Med. 2006 Sep 4;203(9):2063-71. Epub 2006 Aug 28.

12.

CD40 induces macrophage anti-Toxoplasma gondii activity by triggering autophagy-dependent fusion of pathogen-containing vacuoles and lysosomes.

Andrade RM, Wessendarp M, Gubbels MJ, Striepen B, Subauste CS.

J Clin Invest. 2006 Sep;116(9):2366-77.

13.

Toxoplasma gondii-induced activation of EGFR prevents autophagy protein-mediated killing of the parasite.

Muniz-Feliciano L, Van Grol J, Portillo JA, Liew L, Liu B, Carlin CR, Carruthers VB, Matthews S, Subauste CS.

PLoS Pathog. 2013;9(12):e1003809. doi: 10.1371/journal.ppat.1003809. Epub 2013 Dec 19.

14.

p62 Plays a Specific Role in Interferon-γ-Induced Presentation of a Toxoplasma Vacuolar Antigen.

Lee Y, Sasai M, Ma JS, Sakaguchi N, Ohshima J, Bando H, Saitoh T, Akira S, Yamamoto M.

Cell Rep. 2015 Oct 13;13(2):223-33. doi: 10.1016/j.celrep.2015.09.005. Epub 2015 Oct 1.

15.

Toxoplasma gondii ingests and digests host cytosolic proteins.

Dou Z, McGovern OL, Di Cristina M, Carruthers VB.

MBio. 2014 Jul 15;5(4):e01188-14. doi: 10.1128/mBio.01188-14.

16.

Further aspects of Toxoplasma gondii elimination in the presence of metals.

de Carvalho LP, de Melo EJT.

Parasitol Res. 2018 Apr;117(4):1245-1256. doi: 10.1007/s00436-018-5806-x. Epub 2018 Feb 18.

PMID:
29455419
17.
18.

Ubiquitination of pathogen-containing vacuoles promotes host defense to Chlamydia trachomatis and Toxoplasma gondii.

Coers J, Haldar AK.

Commun Integr Biol. 2015 Dec 4;8(6):e1115163. doi: 10.1080/19420889.2015.1115163. eCollection 2015 Nov-Dec.

19.

Ubiquitin systems mark pathogen-containing vacuoles as targets for host defense by guanylate binding proteins.

Haldar AK, Foltz C, Finethy R, Piro AS, Feeley EM, Pilla-Moffett DM, Komatsu M, Frickel EM, Coers J.

Proc Natl Acad Sci U S A. 2015 Oct 13;112(41):E5628-37. doi: 10.1073/pnas.1515966112. Epub 2015 Sep 28.

20.

Toxoplasma gondii sequesters lysosomes from mammalian hosts in the vacuolar space.

Coppens I, Dunn JD, Romano JD, Pypaert M, Zhang H, Boothroyd JC, Joiner KA.

Cell. 2006 Apr 21;125(2):261-74.

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