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Items: 1 to 20 of 117

1.

Telomere biology including TERT rearrangements in neuroblastoma: a useful indicator for surgical treatments.

Kawashima M, Kojima M, Ueda Y, Kurihara S, Hiyama E.

J Pediatr Surg. 2016 Dec;51(12):2080-2085. doi: 10.1016/j.jpedsurg.2016.09.042. Epub 2016 Sep 17.

PMID:
27793328
2.

Clinical features of ATRX or DAXX mutated neuroblastoma.

Kurihara S, Hiyama E, Onitake Y, Yamaoka E, Hiyama K.

J Pediatr Surg. 2014 Dec;49(12):1835-8. doi: 10.1016/j.jpedsurg.2014.09.029. Epub 2014 Nov 14.

PMID:
25487495
3.

Telomerase activation by genomic rearrangements in high-risk neuroblastoma.

Peifer M, Hertwig F, Roels F, Dreidax D, Gartlgruber M, Menon R, Krämer A, Roncaioli JL, Sand F, Heuckmann JM, Ikram F, Schmidt R, Ackermann S, Engesser A, Kahlert Y, Vogel W, Altmüller J, Nürnberg P, Thierry-Mieg J, Thierry-Mieg D, Mariappan A, Heynck S, Mariotti E, Henrich KO, Gloeckner C, Bosco G, Leuschner I, Schweiger MR, Savelyeva L, Watkins SC, Shao C, Bell E, Höfer T, Achter V, Lang U, Theissen J, Volland R, Saadati M, Eggert A, de Wilde B, Berthold F, Peng Z, Zhao C, Shi L, Ortmann M, Büttner R, Perner S, Hero B, Schramm A, Schulte JH, Herrmann C, O'Sullivan RJ, Westermann F, Thomas RK, Fischer M.

Nature. 2015 Oct 29;526(7575):700-4. doi: 10.1038/nature14980. Epub 2015 Oct 14.

4.

Telomere biology in neuroblastoma: telomere binding proteins and alternative strengthening of telomeres.

Onitake Y, Hiyama E, Kamei N, Yamaoka H, Sueda T, Hiyama K.

J Pediatr Surg. 2009 Dec;44(12):2258-66. doi: 10.1016/j.jpedsurg.2009.07.046.

PMID:
20006006
5.

TERT rearrangements are frequent in neuroblastoma and identify aggressive tumors.

Valentijn LJ, Koster J, Zwijnenburg DA, Hasselt NE, van Sluis P, Volckmann R, van Noesel MM, George RE, Tytgat GA, Molenaar JJ, Versteeg R.

Nat Genet. 2015 Dec;47(12):1411-4. doi: 10.1038/ng.3438. Epub 2015 Nov 2.

PMID:
26523776
6.

TERT-mediated and ATRX-mediated Telomere Maintenance and Neuroblastoma.

Duan XF, Zhao Q.

J Pediatr Hematol Oncol. 2018 Jan;40(1):1-6. doi: 10.1097/MPH.0000000000000840. Review.

PMID:
28452859
7.

Alternative lengthening of telomeres phenotype in malignant vascular tumors is highly associated with loss of ATRX expression and is frequently observed in hepatic angiosarcomas.

Liau JY, Tsai JH, Yang CY, Lee JC, Liang CW, Hsu HH, Jeng YM.

Hum Pathol. 2015 Sep;46(9):1360-6. doi: 10.1016/j.humpath.2015.05.019. Epub 2015 Jun 5.

PMID:
26190196
8.

Leiomyosarcoma with alternative lengthening of telomeres is associated with aggressive histologic features, loss of ATRX expression, and poor clinical outcome.

Liau JY, Tsai JH, Jeng YM, Lee JC, Hsu HH, Yang CY.

Am J Surg Pathol. 2015 Feb;39(2):236-44. doi: 10.1097/PAS.0000000000000324.

PMID:
25229770
9.

TERT Promoter Mutations but not the Alternative Lengthening of Telomeres Phenotype Are Present in a Subset of Ependymomas and Are Associated With Adult Onset and Progression to Ependymosarcoma.

Brügger F, Dettmer MS, Neuenschwander M, Perren A, Marinoni I, Hewer E.

J Neuropathol Exp Neurol. 2017 Jan 1;76(1):61-66. doi: 10.1093/jnen/nlw106.

PMID:
28040793
10.

Loss of wild-type ATRX expression in somatic cell hybrids segregates with activation of Alternative Lengthening of Telomeres.

Bower K, Napier CE, Cole SL, Dagg RA, Lau LM, Duncan EL, Moy EL, Reddel RR.

PLoS One. 2012;7(11):e50062. doi: 10.1371/journal.pone.0050062. Epub 2012 Nov 20.

11.

Alternative lengthening of telomeres--an enhanced chromosomal instability in aggressive non-MYCN amplified and telomere elongated neuroblastomas.

Lundberg G, Sehic D, Länsberg JK, Øra I, Frigyesi A, Castel V, Navarro S, Piqueras M, Martinsson T, Noguera R, Gisselsson D.

Genes Chromosomes Cancer. 2011 Apr;50(4):250-62. doi: 10.1002/gcc.20850. Epub 2011 Jan 14.

PMID:
21319260
12.

Telomere maintenance is pivotal for high-risk neuroblastoma.

Hertwig F, Peifer M, Fischer M.

Cell Cycle. 2016;15(3):311-2. doi: 10.1080/15384101.2015.1125243. Epub 2015 Dec 10. No abstract available.

13.

Systematic analysis of telomere length and somatic alterations in 31 cancer types.

Barthel FP, Wei W, Tang M, Martinez-Ledesma E, Hu X, Amin SB, Akdemir KC, Seth S, Song X, Wang Q, Lichtenberg T, Hu J, Zhang J, Zheng S, Verhaak RG.

Nat Genet. 2017 Mar;49(3):349-357. doi: 10.1038/ng.3781. Epub 2017 Jan 30.

14.

Telomere length abnormalities and telomerase RNA component expression in gastroenteropancreatic neuroendocrine tumors.

Kim HS, Lee HS, Nam KH, Choi J, Kim WH.

Anticancer Res. 2015 Jun;35(6):3501-10.

PMID:
26026117
15.

Telomerase activity in neuroblastoma: is it a prognostic indicator of clinical behaviour?

Hiyama E, Hiyama K, Ohtsu K, Yamaoka H, Ichikawa T, Shay JW, Yokoyama T.

Eur J Cancer. 1997 Oct;33(12):1932-6.

PMID:
9516827
16.

Telomerase-dependent and independent telomere maintenance and its clinical implications in medullary thyroid carcinoma.

Wang N, Xu D, Sofiadis A, Höög A, Vukojević V, Bäckdahl M, Zedenius J, Larsson C.

J Clin Endocrinol Metab. 2014 Aug;99(8):E1571-9. doi: 10.1210/jc.2014-1158. Epub 2014 Apr 23.

17.

Telomerase reverse transcriptase expression protects transformed human cells against DNA-damaging agents, and increases tolerance to chromosomal instability.

Fleisig HB, Hukezalie KR, Thompson CA, Au-Yeung TT, Ludlow AT, Zhao CR, Wong JM.

Oncogene. 2016 Jan 14;35(2):218-27. doi: 10.1038/onc.2015.75. Epub 2015 Apr 20.

PMID:
25893297
18.

Altered telomeres in tumors with ATRX and DAXX mutations.

Heaphy CM, de Wilde RF, Jiao Y, Klein AP, Edil BH, Shi C, Bettegowda C, Rodriguez FJ, Eberhart CG, Hebbar S, Offerhaus GJ, McLendon R, Rasheed BA, He Y, Yan H, Bigner DD, Oba-Shinjo SM, Marie SK, Riggins GJ, Kinzler KW, Vogelstein B, Hruban RH, Maitra A, Papadopoulos N, Meeker AK.

Science. 2011 Jul 22;333(6041):425. doi: 10.1126/science.1207313. Epub 2011 Jun 30.

19.

Alternative lengthening of telomeres does exist in various canine sarcomas.

Kreilmeier T, Sampl S, Deloria AJ, Walter I, Reifinger M, Hauck M, Borst LB, Holzmann K, Kleiter M.

Mol Carcinog. 2017 Mar;56(3):923-935. doi: 10.1002/mc.22546. Epub 2016 Sep 22.

PMID:
27585244
20.

Disease mutant analysis identifies a new function of DAXX in telomerase regulation and telomere maintenance.

Tang M, Li Y, Zhang Y, Chen Y, Huang W, Wang D, Zaug AJ, Liu D, Zhao Y, Cech TR, Ma W, Songyang Z.

J Cell Sci. 2015 Jan 15;128(2):331-41. doi: 10.1242/jcs.159467. Epub 2014 Nov 21.

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