Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 99

1.

Design and Synthesis of Cajanine Analogues against Hepatitis C Virus through Down-Regulating Host Chondroitin Sulfate N-Acetylgalactosaminyltransferase 1.

Ji XY, Chen JH, Zheng GH, Huang MH, Zhang L, Yi H, Jin J, Jiang JD, Peng ZG, Li ZR.

J Med Chem. 2016 Nov 23;59(22):10268-10284. Epub 2016 Nov 7.

PMID:
27783522
2.

Discovery and evolution of aloperine derivatives as a new family of HCV inhibitors with novel mechanism.

Zhang X, Lv XQ, Tang S, Mei L, Li YH, Zhang JP, Jiang JD, Peng ZG, Song DQ.

Eur J Med Chem. 2018 Jan 1;143:1053-1065. doi: 10.1016/j.ejmech.2017.12.002. Epub 2017 Dec 5.

PMID:
29232582
3.

Synthesis and hepatitis C antiviral activity of 1-aminobenzyl-1H-indazole-3-carboxamide analogues.

Shi JJ, Ji FH, He PL, Yang YX, Tang W, Zuo JP, Li YC.

ChemMedChem. 2013 May;8(5):722-5. doi: 10.1002/cmdc.201300083. Epub 2013 Mar 19.

PMID:
23512654
4.

Discovery of 2-iminobenzimidazoles as potent hepatitis C virus inhibitors with a novel mechanism of action.

Windisch MP, Jo S, Kim HY, Kim SH, Kim K, Kong S, Jeong H, Ahn S, No Z, Hwang JY.

Eur J Med Chem. 2014 May 6;78:35-42. doi: 10.1016/j.ejmech.2014.03.030. Epub 2014 Mar 13.

PMID:
24675178
5.

Recent advances on the synthesis of hepatitis C virus NS5B RNA-dependent RNA-polymerase inhibitors.

Zhao C, Wang Y, Ma S.

Eur J Med Chem. 2015 Sep 18;102:188-214. doi: 10.1016/j.ejmech.2015.07.046. Epub 2015 Jul 31. Review.

PMID:
26276434
6.

Discovery of the 2-phenyl-4,5,6,7-Tetrahydro-1H-indole as a novel anti-hepatitis C virus targeting scaffold.

Andreev IA, Manvar D, Barreca ML, Belov DS, Basu A, Sweeney NL, Ratmanova NK, Lukyanenko ER, Manfroni G, Cecchetti V, Frick DN, Altieri A, Kaushik-Basu N, Kurkin AV.

Eur J Med Chem. 2015;96:250-8. doi: 10.1016/j.ejmech.2015.04.022. Epub 2015 Apr 10.

7.

Novel 4-thiazolidinones as non-nucleoside inhibitors of hepatitis C virus NS5B RNA-dependent RNA polymerase.

Çakir G, Küçükgüzel İ, Guhamazumder R, Tatar E, Manvar D, Basu A, Patel BA, Zia J, Talele TT, Kaushik-Basu N.

Arch Pharm (Weinheim). 2015 Jan;348(1):10-22. doi: 10.1002/ardp.201400247. Epub 2014 Dec 2.

PMID:
25449674
8.

C-6 aryl substituted 4-quinolone-3-carboxylic acids as inhibitors of hepatitis C virus.

Chen YL, Zacharias J, Vince R, Geraghty RJ, Wang Z.

Bioorg Med Chem. 2012 Aug 1;20(15):4790-800. doi: 10.1016/j.bmc.2012.05.066. Epub 2012 Jun 7.

PMID:
22748708
9.

New 1-phenyl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides inhibit hepatitis C virus replication via suppression of cyclooxygenase-2.

Manvar D, Pelliccia S, La Regina G, Famiglini V, Coluccia A, Ruggieri A, Anticoli S, Lee JC, Basu A, Cevik O, Nencioni L, Palamara AT, Zamperini C, Botta M, Neyts J, Leyssen P, Kaushik-Basu N, Silvestri R.

Eur J Med Chem. 2015 Jan 27;90:497-506. doi: 10.1016/j.ejmech.2014.11.042. Epub 2014 Nov 27.

PMID:
25483263
10.

The design, synthesis, and antiviral activity of 4'-azidocytidine analogues against hepatitis C virus replication: the discovery of 4'-azidoarabinocytidine.

Smith DB, Kalayanov G, Sund C, Winqvist A, Pinho P, Maltseva T, Morisson V, Leveque V, Rajyaguru S, Le Pogam S, Najera I, Benkestock K, Zhou XX, Maag H, Cammack N, Martin JA, Swallow S, Johansson NG, Klumpp K, Smith M.

J Med Chem. 2009 Jan 8;52(1):219-23. doi: 10.1021/jm800981y.

PMID:
19055482
11.

Discovery of Novel Small Molecule Anti-HCV Agents via the CypA Inhibitory Mechanism Using O-Acylation-Directed Lead Optimization.

Yan W, Qing J, Mei H, Mao F, Huang J, Zhu J, Jiang H, Liu L, Zhang L, Li J.

Molecules. 2015 Jun 4;20(6):10342-59. doi: 10.3390/molecules200610342.

12.
13.

Avasimibe: A novel hepatitis C virus inhibitor that targets the assembly of infectious viral particles.

Hu L, Li J, Cai H, Yao W, Xiao J, Li YP, Qiu X, Xia H, Peng T.

Antiviral Res. 2017 Dec;148:5-14. doi: 10.1016/j.antiviral.2017.10.016. Epub 2017 Oct 23.

PMID:
29074218
14.

Characterization and structure-activity relationship study of iminodipyridinopyrimidines as novel hepatitis C virus inhibitor.

Park DS, Jo E, Choi J, Lee M, Kim S, Kim HY, Nam J, Ahn S, Hwang JY, Windisch MP.

Eur J Med Chem. 2017 Nov 10;140:65-73. doi: 10.1016/j.ejmech.2017.09.010. Epub 2017 Sep 6.

PMID:
28923387
15.

Daclatasvir-like inhibitors of NS5A block early biogenesis of hepatitis C virus-induced membranous replication factories, independent of RNA replication.

Berger C, Romero-Brey I, Radujkovic D, Terreux R, Zayas M, Paul D, Harak C, Hoppe S, Gao M, Penin F, Lohmann V, Bartenschlager R.

Gastroenterology. 2014 Nov;147(5):1094-105.e25. doi: 10.1053/j.gastro.2014.07.019. Epub 2014 Jul 18.

16.

Discovery and structure-activity relationships study of novel thieno[2,3-b]pyridine analogues as hepatitis C virus inhibitors.

Wang NY, Zuo WQ, Xu Y, Gao C, Zeng XX, Zhang LD, You XY, Peng CT, Shen Y, Yang SY, Wei YQ, Yu LT.

Bioorg Med Chem Lett. 2014 Mar 15;24(6):1581-8. doi: 10.1016/j.bmcl.2014.01.075. Epub 2014 Feb 3.

PMID:
24529869
17.

The discovery of IDX21437: Design, synthesis and antiviral evaluation of 2'-α-chloro-2'-β-C-methyl branched uridine pronucleotides as potent liver-targeted HCV polymerase inhibitors.

Alexandre FR, Badaroux E, Bilello JP, Bot S, Bouisset T, Brandt G, Cappelle S, Chapron C, Chaves D, Convard T, Counor C, Da Costa D, Dukhan D, Gay M, Gosselin G, Griffon JF, Gupta K, Hernandez-Santiago B, La Colla M, Lioure MP, Milhau J, Paparin JL, Peyronnet J, Parsy C, Pierra Rouvière C, Rahali H, Rahali R, Salanson A, Seifer M, Serra I, Standring D, Surleraux D, Dousson CB.

Bioorg Med Chem Lett. 2017 Sep 15;27(18):4323-4330. doi: 10.1016/j.bmcl.2017.08.029. Epub 2017 Aug 16.

PMID:
28835346
18.

Synthesis and anti-HCV activity evaluation of anilinoquinoline derivatives.

Peng HK, Lin CK, Yang SY, Tseng CK, Tzeng CC, Lee JC, Yang SC.

Bioorg Med Chem Lett. 2012 Jan 15;22(2):1107-10. doi: 10.1016/j.bmcl.2011.11.121. Epub 2011 Dec 4.

PMID:
22204909
19.

N-substituted benzyl matrinic acid derivatives inhibit hepatitis C virus (HCV) replication through down-regulating host heat-stress cognate 70 (Hsc70) expression.

Du NN, Peng ZG, Bi CW, Tang S, Li YH, Li JR, Zhu YP, Zhang JP, Wang YX, Jiang JD, Song DQ.

PLoS One. 2013;8(3):e58675. doi: 10.1371/journal.pone.0058675. Epub 2013 Mar 14.

20.

Synthesis and antiviral properties of novel 7-heterocyclic substituted 7-deaza-adenine nucleoside inhibitors of Hepatitis C NS5B polymerase.

Di Francesco ME, Avolio S, Pompei M, Pesci S, Monteagudo E, Pucci V, Giuliano C, Fiore F, Rowley M, Summa V.

Bioorg Med Chem. 2012 Aug 1;20(15):4801-11. doi: 10.1016/j.bmc.2012.05.067. Epub 2012 Jun 6.

PMID:
22770556

Supplemental Content

Support Center