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Items: 1 to 20 of 81

1.

Long-Range Signaling in MutS and MSH Homologs via Switching of Dynamic Communication Pathways.

Wang B, Francis J, Sharma M, Law SM, Predeus AV, Feig M.

PLoS Comput Biol. 2016 Oct 21;12(10):e1005159. doi: 10.1371/journal.pcbi.1005159. eCollection 2016 Oct.

2.

Deciphering the mismatch recognition cycle in MutS and MSH2-MSH6 using normal-mode analysis.

Mukherjee S, Law SM, Feig M.

Biophys J. 2009 Mar 4;96(5):1707-20. doi: 10.1016/j.bpj.2008.10.071.

3.

Slow conformational changes in MutS and DNA direct ordered transitions between mismatch search, recognition and signaling of DNA repair.

Sharma A, Doucette C, Biro FN, Hingorani MM.

J Mol Biol. 2013 Nov 15;425(22):4192-205. doi: 10.1016/j.jmb.2013.08.011. Epub 2013 Aug 20.

4.

Mechanism for verification of mismatched and homoduplex DNAs by nucleotides-bound MutS analyzed by molecular dynamics simulations.

Ishida H, Matsumoto A.

Proteins. 2016 Sep;84(9):1287-303. doi: 10.1002/prot.25077. Epub 2016 Jun 15.

PMID:
27238299
5.

Chemical trapping of the dynamic MutS-MutL complex formed in DNA mismatch repair in Escherichia coli.

Winkler I, Marx AD, Lariviere D, Heinze RJ, Cristovao M, Reumer A, Curth U, Sixma TK, Friedhoff P.

J Biol Chem. 2011 May 13;286(19):17326-37. doi: 10.1074/jbc.M110.187641. Epub 2011 Mar 15.

6.

Large conformational changes in MutS during DNA scanning, mismatch recognition and repair signalling.

Qiu R, DeRocco VC, Harris C, Sharma A, Hingorani MM, Erie DA, Weninger KR.

EMBO J. 2012 May 30;31(11):2528-40. doi: 10.1038/emboj.2012.95. Epub 2012 Apr 13. Erratum in: EMBO J. 2019 Feb 15;38(4):.

7.

Atomic force microscopy captures the initiation of methyl-directed DNA mismatch repair.

Josephs EA, Zheng T, Marszalek PE.

DNA Repair (Amst). 2015 Nov;35:71-84. doi: 10.1016/j.dnarep.2015.08.006. Epub 2015 Sep 21.

8.

Is thymidine glycol containing DNA a substrate of E. coli DNA mismatch repair system?

Perevozchikova SA, Trikin RM, Heinze RJ, Romanova EA, Oretskaya TS, Friedhoff P, Kubareva EA.

PLoS One. 2014 Aug 18;9(8):e104963. doi: 10.1371/journal.pone.0104963. eCollection 2014. Erratum in: PLoS One. 2015;10(2):e0118035.

9.

Evolutionary Covariance Combined with Molecular Dynamics Predicts a Framework for Allostery in the MutS DNA Mismatch Repair Protein.

Lakhani B, Thayer KM, Hingorani MM, Beveridge DL.

J Phys Chem B. 2017 Mar 9;121(9):2049-2061. doi: 10.1021/acs.jpcb.6b11976. Epub 2017 Feb 24.

10.

The effects of nucleotides on MutS-DNA binding kinetics clarify the role of MutS ATPase activity in mismatch repair.

Jacobs-Palmer E, Hingorani MM.

J Mol Biol. 2007 Mar 2;366(4):1087-98. Epub 2006 Dec 6.

11.

The molecular mechanism of DNA damage recognition by MutS homologs and its consequences for cell death response.

Salsbury FR Jr, Clodfelter JE, Gentry MB, Hollis T, Scarpinato KD.

Nucleic Acids Res. 2006 Apr 28;34(8):2173-85. Print 2006.

12.

Mechanism of MutS searching for DNA mismatches and signaling repair.

Tessmer I, Yang Y, Zhai J, Du C, Hsieh P, Hingorani MM, Erie DA.

J Biol Chem. 2008 Dec 26;283(52):36646-54. doi: 10.1074/jbc.M805712200. Epub 2008 Oct 14.

13.

Single-molecule FRET TACKLE reveals highly dynamic mismatched DNA-MutS complexes.

Sass LE, Lanyi C, Weninger K, Erie DA.

Biochemistry. 2010 Apr 13;49(14):3174-90. doi: 10.1021/bi901871u.

14.

Trapping and visualizing intermediate steps in the mismatch repair pathway in vivo.

Lenhart JS, Pillon MC, Guarné A, Simmons LA.

Mol Microbiol. 2013 Nov;90(4):680-98. doi: 10.1111/mmi.12389. Epub 2013 Sep 16.

15.

Dynamical allosterism in the mechanism of action of DNA mismatch repair protein MutS.

Pieniazek SN, Hingorani MM, Beveridge DL.

Biophys J. 2011 Oct 5;101(7):1730-9. doi: 10.1016/j.bpj.2011.08.039.

16.

ATP increases the affinity between MutS ATPase domains. Implications for ATP hydrolysis and conformational changes.

Lamers MH, Georgijevic D, Lebbink JH, Winterwerp HH, Agianian B, de Wind N, Sixma TK.

J Biol Chem. 2004 Oct 15;279(42):43879-85. Epub 2004 Aug 4.

17.

Modulation of MutS ATP-dependent functional activities by DNA containing a cisplatin compound lesion (base damage and mismatch).

Sedletska Y, Fourrier L, Malinge JM.

J Mol Biol. 2007 May 25;369(1):27-40. Epub 2007 Feb 22.

PMID:
17400248
18.

MutS/MutL crystal structure reveals that the MutS sliding clamp loads MutL onto DNA.

Groothuizen FS, Winkler I, Cristóvão M, Fish A, Winterwerp HH, Reumer A, Marx AD, Hermans N, Nicholls RA, Murshudov GN, Lebbink JH, Friedhoff P, Sixma TK.

Elife. 2015 Jul 11;4:e06744. doi: 10.7554/eLife.06744.

19.

Magnesium coordination controls the molecular switch function of DNA mismatch repair protein MutS.

Lebbink JH, Fish A, Reumer A, Natrajan G, Winterwerp HH, Sixma TK.

J Biol Chem. 2010 Apr 23;285(17):13131-41. doi: 10.1074/jbc.M109.066001. Epub 2010 Feb 18.

20.

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