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Items: 1 to 20 of 113

1.

Helicobacter pylori exploits human CEACAMs via HopQ for adherence and translocation of CagA.

Königer V, Holsten L, Harrison U, Busch B, Loell E, Zhao Q, Bonsor DA, Roth A, Kengmo-Tchoupa A, Smith SI, Mueller S, Sundberg EJ, Zimmermann W, Fischer W, Hauck CR, Haas R.

Nat Microbiol. 2016 Oct 17;2:16188. doi: 10.1038/nmicrobiol.2016.188. Erratum in: Nat Microbiol. 2016 Oct 31;2:16233.

PMID:
27748756
2.

Helicobacter pylori adhesin HopQ engages in a virulence-enhancing interaction with human CEACAMs.

Javaheri A, Kruse T, Moonens K, Mejías-Luque R, Debraekeleer A, Asche CI, Tegtmeyer N, Kalali B, Bach NC, Sieber SA, Hill DJ, Königer V, Hauck CR, Moskalenko R, Haas R, Busch DH, Klaile E, Slevogt H, Schmidt A, Backert S, Remaut H, Singer BB, Gerhard M.

Nat Microbiol. 2016 Oct 17;2:16189. doi: 10.1038/nmicrobiol.2016.189. Erratum in: Nat Microbiol. 2016 Nov 07;2:16243.

PMID:
27748768
3.

HopQ impacts the integrin α5β1-independent NF-κB activation by Helicobacter pylori in CEACAM expressing cells.

Feige MH, Sokolova O, Pickenhahn A, Maubach G, Naumann M.

Int J Med Microbiol. 2018 Jul;308(5):527-533. doi: 10.1016/j.ijmm.2018.05.003. Epub 2018 May 14.

PMID:
29779861
4.

The Helicobacter pylori adhesin protein HopQ exploits the dimer interface of human CEACAMs to facilitate translocation of the oncoprotein CagA.

Bonsor DA, Zhao Q, Schmidinger B, Weiss E, Wang J, Deredge D, Beadenkopf R, Dow B, Fischer W, Beckett D, Wintrode PL, Haas R, Sundberg EJ.

EMBO J. 2018 Jul 2;37(13). pii: e98664. doi: 10.15252/embj.201798664. Epub 2018 May 3.

PMID:
29724755
5.

Helicobacter pylori adhesin HopQ disrupts trans dimerization in human CEACAMs.

Moonens K, Hamway Y, Neddermann M, Reschke M, Tegtmeyer N, Kruse T, Kammerer R, Mejías-Luque R, Singer BB, Backert S, Gerhard M, Remaut H.

EMBO J. 2018 Jul 2;37(13). pii: e98665. doi: 10.15252/embj.201798665. Epub 2018 Jun 1.

PMID:
29858229
6.

Helicobacter pylori type IV secretion apparatus exploits beta1 integrin in a novel RGD-independent manner.

Jiménez-Soto LF, Kutter S, Sewald X, Ertl C, Weiss E, Kapp U, Rohde M, Pirch T, Jung K, Retta SF, Terradot L, Fischer W, Haas R.

PLoS Pathog. 2009 Dec;5(12):e1000684. doi: 10.1371/journal.ppat.1000684. Epub 2009 Dec 4.

7.

An RGD helper sequence in CagL of Helicobacter pylori assists in interactions with integrins and injection of CagA.

Conradi J, Tegtmeyer N, Woźna M, Wissbrock M, Michalek C, Gagell C, Cover TL, Frank R, Sewald N, Backert S.

Front Cell Infect Microbiol. 2012 May 23;2:70. doi: 10.3389/fcimb.2012.00070. eCollection 2012.

8.

Helicobacter pylori interferes with leukocyte migration via the outer membrane protein HopQ and via CagA translocation.

Busch B, Weimer R, Woischke C, Fischer W, Haas R.

Int J Med Microbiol. 2015 May;305(3):355-64. doi: 10.1016/j.ijmm.2015.02.003. Epub 2015 Feb 14.

PMID:
25736449
9.

Type IV Secretion and Signal Transduction of Helicobacter pylori CagA through Interactions with Host Cell Receptors.

Backert S, Tegtmeyer N.

Toxins (Basel). 2017 Mar 24;9(4). pii: E115. doi: 10.3390/toxins9040115. Review.

10.

Helicobacter pylori HopQ outer membrane protein attenuates bacterial adherence to gastric epithelial cells.

Loh JT, Torres VJ, Algood HM, McClain MS, Cover TL.

FEMS Microbiol Lett. 2008 Dec;289(1):53-8.

11.

Dynamics of the Cag-type IV secretion system of Helicobacter pylori as studied by bacterial co-infections.

Jiménez-Soto LF, Clausen S, Sprenger A, Ertl C, Haas R.

Cell Microbiol. 2013 Nov;15(11):1924-37. doi: 10.1111/cmi.12166. Epub 2013 Aug 8.

PMID:
23844976
12.

The Helicobacter pylori Type IV Secretion System Encoded by the cag Pathogenicity Island: Architecture, Function, and Signaling.

Backert S, Haas R, Gerhard M, Naumann M.

Curr Top Microbiol Immunol. 2017;413:187-220. doi: 10.1007/978-3-319-75241-9_8.

PMID:
29536360
13.

Structural Insights into Helicobacter pylori Cag Protein Interactions with Host Cell Factors.

Bergé C, Terradot L.

Curr Top Microbiol Immunol. 2017;400:129-147. doi: 10.1007/978-3-319-50520-6_6. Review.

PMID:
28124152
14.

Neisseria meningitidis has two independent modes of recognizing its human receptor CEACAM1.

Kuespert K, Roth A, Hauck CR.

PLoS One. 2011 Jan 27;6(1):e14609. doi: 10.1371/journal.pone.0014609.

15.

The coupling protein Cagbeta and its interaction partner CagZ are required for type IV secretion of the Helicobacter pylori CagA protein.

Jurik A, Hausser E, Kutter S, Pattis I, Prassl S, Weiss E, Fischer W.

Infect Immun. 2010 Dec;78(12):5244-51. doi: 10.1128/IAI.00796-10. Epub 2010 Sep 27.

16.

Helicobacter pylori exploits a unique repertoire of type IV secretion system components for pilus assembly at the bacteria-host cell interface.

Shaffer CL, Gaddy JA, Loh JT, Johnson EM, Hill S, Hennig EE, McClain MS, McDonald WH, Cover TL.

PLoS Pathog. 2011 Sep;7(9):e1002237. doi: 10.1371/journal.ppat.1002237. Epub 2011 Sep 1.

17.
18.

Molecular dissection of protein-protein interactions between integrin α5β1 and the Helicobacter pylori Cag type IV secretion system.

Koelblen T, Bergé C, Cherrier MV, Brillet K, Jimenez-Soto L, Ballut L, Takagi J, Montserret R, Rousselle P, Fischer W, Haas R, Fronzes R, Terradot L.

FEBS J. 2017 Dec;284(23):4143-4157. doi: 10.1111/febs.14299. Epub 2017 Nov 12.

PMID:
29055076
19.

Structural insights into Helicobacter pylori oncoprotein CagA interaction with β1 integrin.

Kaplan-Türköz B, Jiménez-Soto LF, Dian C, Ertl C, Remaut H, Louche A, Tosi T, Haas R, Terradot L.

Proc Natl Acad Sci U S A. 2012 Sep 4;109(36):14640-5. doi: 10.1073/pnas.1206098109. Epub 2012 Aug 20.

20.

The Middle Fragment of Helicobacter pylori CagA Induces Actin Rearrangement and Triggers Its Own Uptake into Gastric Epithelial Cells.

Tohidpour A, Gorrell RJ, Roujeinikova A, Kwok T.

Toxins (Basel). 2017 Jul 28;9(8). pii: E237. doi: 10.3390/toxins9080237.

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