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Items: 1 to 20 of 91

1.
2.

Lipid-soluble ginseng extract induces apoptosis and G0/G1 cell cycle arrest in NCI-H460 human lung cancer cells.

Kang MR, Kim HM, Kang JS, Lee K, Lee SD, Hyun DH, In MJ, Park SK, Kim DC.

Plant Foods Hum Nutr. 2011 Jun;66(2):101-6. doi: 10.1007/s11130-011-0232-6.

PMID:
21611769
3.

Mitochondrial function in human neuroblastoma cells is up-regulated and protected by NQO1, a plasma membrane redox enzyme.

Kim J, Kim SK, Kim HK, Mattson MP, Hyun DH.

PLoS One. 2013 Jul 11;8(7):e69030. doi: 10.1371/journal.pone.0069030. Print 2013.

4.

The plasma membrane redox enzyme NQO1 sustains cellular energetics and protects human neuroblastoma cells against metabolic and proteotoxic stress.

Hyun DH, Kim J, Moon C, Lim CJ, de Cabo R, Mattson MP.

Age (Dordr). 2012 Apr;34(2):359-70. doi: 10.1007/s11357-011-9245-1. Epub 2011 Apr 13.

5.
6.

Facilitation of 9,10-phenanthrenequinone-elicited neuroblastoma cell apoptosis by NAD(P)H:quinone oxidoreductase 1.

Matsunaga T, Kamase K, Takasawa H, Yamaji Y, Endo S, El-Kabbani O, Ikari A.

Chem Biol Interact. 2018 Jan 5;279:10-20. doi: 10.1016/j.cbi.2017.10.028. Epub 2017 Nov 10.

PMID:
29108775
7.

Induction of chemoprotective phase 2 enzymes by ginseng and its components.

Lee LS, Stephenson KK, Fahey JW, Parsons TL, Lietman PS, Andrade AS, Lei X, Yun H, Soon GH, Shen P, Danishefsky S, Flexner C.

Planta Med. 2009 Aug;75(10):1129-33. doi: 10.1055/s-0029-1185508. Epub 2009 Mar 26.

PMID:
19326326
8.
9.

An NQO1- and PARP-1-mediated cell death pathway induced in non-small-cell lung cancer cells by beta-lapachone.

Bey EA, Bentle MS, Reinicke KE, Dong Y, Yang CR, Girard L, Minna JD, Bornmann WG, Gao J, Boothman DA.

Proc Natl Acad Sci U S A. 2007 Jul 10;104(28):11832-7. Epub 2007 Jul 3.

10.

Cytotoxicity of RH1: NAD(P)H:quinone acceptor oxidoreductase (NQO1)-independent oxidative stress and apoptosis induction.

Tudor G, Alley M, Nelson CM, Huang R, Covell DG, Gutierrez P, Sausville EA.

Anticancer Drugs. 2005 Apr;16(4):381-91.

PMID:
15746574
11.

Antimelanoma activity of the redox dye DCPIP (2,6-dichlorophenolindophenol) is antagonized by NQO1.

Cabello CM, Bair WB 3rd, Bause AS, Wondrak GT.

Biochem Pharmacol. 2009 Aug 15;78(4):344-54. doi: 10.1016/j.bcp.2009.04.016. Epub 2009 Apr 24.

12.

The NQO1 bioactivatable drug, β-lapachone, alters the redox state of NQO1+ pancreatic cancer cells, causing perturbation in central carbon metabolism.

Silvers MA, Deja S, Singh N, Egnatchik RA, Sudderth J, Luo X, Beg MS, Burgess SC, DeBerardinis RJ, Boothman DA, Merritt ME.

J Biol Chem. 2017 Nov 3;292(44):18203-18216. doi: 10.1074/jbc.M117.813923. Epub 2017 Sep 15.

PMID:
28916726
13.

Lipid-soluble ginseng extract inhibits invasion and metastasis of B16F10 melanoma cells.

Yun J, Kim BG, Kang JS, Park SK, Lee K, Hyun DH, Kim HM, In MJ, Kim DC.

J Med Food. 2015 Jan;18(1):102-8. doi: 10.1089/jmf.2013.3138.

14.

Overexpression of NQO1 protects human SK-N-MC neuroblastoma cells against dopamine-induced cell death.

Zafar KS, Inayat-Hussain SH, Siegel D, Bao A, Shieh B, Ross D.

Toxicol Lett. 2006 Oct 25;166(3):261-7. Epub 2006 Aug 15.

PMID:
16978807
15.

Hydroxytyrosol induces phase II detoxifying enzyme expression and effectively protects dopaminergic cells against dopamine- and 6-hydroxydopamine induced cytotoxicity.

Yu G, Deng A, Tang W, Ma J, Yuan C, Ma J.

Neurochem Int. 2016 Jun;96:113-20. doi: 10.1016/j.neuint.2016.03.005. Epub 2016 Mar 9.

PMID:
26970393
16.

Protection against 1-methyl-4-phenylpyridinium ion (MPP+)-induced apoptosis by water extract of ginseng (Panax ginseng C.A. Meyer) in SH-SY5Y cells.

Hu S, Han R, Mak S, Han Y.

J Ethnopharmacol. 2011 Apr 26;135(1):34-42. doi: 10.1016/j.jep.2011.02.017. Epub 2011 Feb 22.

PMID:
21349320
17.

The variable chemotherapeutic response of Malabaricone-A in leukemic and solid tumor cell lines depends on the degree of redox imbalance.

Manna A, De Sarkar S, De S, Bauri AK, Chattopadhyay S, Chatterjee M.

Phytomedicine. 2015 Jul 15;22(7-8):713-23. doi: 10.1016/j.phymed.2015.05.007. Epub 2015 May 29.

PMID:
26141757
18.

NQO1 involves in the imine bond reduction of sanguinarine and recombinant adeno-associated virus mediated NQO1 overexpression decreases sanguinarine-induced cytotoxicity in rat BRL cells.

Zhang DS, Liu ZY, Li YJ, Sun ZL.

Toxicol Lett. 2014 Feb 10;225(1):119-29. doi: 10.1016/j.toxlet.2013.11.028. Epub 2013 Dec 1.

PMID:
24300172
19.

NAD(P)H:quinone oxidoreductase 1 is induced by progesterone in cardiomyocytes.

Morrissy S, Strom J, Purdom-Dickinson S, Chen QM.

Cardiovasc Toxicol. 2012 Jun;12(2):108-14. doi: 10.1007/s12012-011-9144-9.

20.

Dicoumarol enhances gemcitabine-induced cytotoxicity in high NQO1-expressing cholangiocarcinoma cells.

Buranrat B, Prawan A, Kukongviriyapan U, Kongpetch S, Kukongviriyapan V.

World J Gastroenterol. 2010 May 21;16(19):2362-70.

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