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Herpes Simplex Virus 1 Tegument Protein UL41 Counteracts IFIT3 Antiviral Innate Immunity.

Jiang Z, Su C, Zheng C.

J Virol. 2016 Nov 28;90(24):11056-11061. Print 2016 Dec 15.


Herpes Simplex Virus 1 Abrogates the cGAS/STING-Mediated Cytosolic DNA-Sensing Pathway via Its Virion Host Shutoff Protein, UL41.

Su C, Zheng C.

J Virol. 2017 Feb 28;91(6). pii: e02414-16. doi: 10.1128/JVI.02414-16. Print 2017 Mar 15.


Herpes simplex virus 1 UL41 protein abrogates the antiviral activity of hZAP by degrading its mRNA.

Su C, Zhang J, Zheng C.

Virol J. 2015 Dec 1;12:203. doi: 10.1186/s12985-015-0433-y.


Herpes Simplex Virus 1 UL36USP Antagonizes Type I Interferon-Mediated Antiviral Innate Immunity.

Yuan H, You J, You H, Zheng C.

J Virol. 2018 Sep 12;92(19). pii: e01161-18. doi: 10.1128/JVI.01161-18. Print 2018 Oct 1.


Herpes simplex virus type 1 abrogates the antiviral activity of Ch25h via its virion host shutoff protein.

You H, Yuan H, Fu W, Su C, Wang W, Cheng T, Zheng C.

Antiviral Res. 2017 Jul;143:69-73. doi: 10.1016/j.antiviral.2017.04.004. Epub 2017 Apr 9.


Herpes Simplex Virus 1 Tegument Protein VP22 Abrogates cGAS/STING-Mediated Antiviral Innate Immunity.

Huang J, You H, Su C, Li Y, Chen S, Zheng C.

J Virol. 2018 Jul 17;92(15). pii: e00841-18. doi: 10.1128/JVI.00841-18. Print 2018 Aug 1.


Herpes Simplex Virus 1 UL41 Protein Suppresses the IRE1/XBP1 Signal Pathway of the Unfolded Protein Response via Its RNase Activity.

Zhang P, Su C, Jiang Z, Zheng C.

J Virol. 2017 Jan 31;91(4). pii: e02056-16. doi: 10.1128/JVI.02056-16. Print 2017 Feb 15.


Novel Role for Protein Inhibitor of Activated STAT 4 (PIAS4) in the Restriction of Herpes Simplex Virus 1 by the Cellular Intrinsic Antiviral Immune Response.

Conn KL, Wasson P, McFarlane S, Tong L, Brown JR, Grant KG, Domingues P, Boutell C.

J Virol. 2016 Apr 14;90(9):4807-4826. doi: 10.1128/JVI.03055-15. Print 2016 May.


Herpes simplex virus 1 counteracts viperin via its virion host shutoff protein UL41.

Shen G, Wang K, Wang S, Cai M, Li ML, Zheng C.

J Virol. 2014 Oct;88(20):12163-6. doi: 10.1128/JVI.01380-14. Epub 2014 Jul 30.


Herpes simplex virus is equipped with RNA- and protein-based mechanisms to repress expression of ATRX, an effector of intrinsic immunity.

Jurak I, Silverstein LB, Sharma M, Coen DM.

J Virol. 2012 Sep;86(18):10093-102. doi: 10.1128/JVI.00930-12. Epub 2012 Jul 11.


Attenuated Herpes Simplex Virus 1 (HSV-1) Expressing a Mutant Form of ICP6 Stimulates a Strong Immune Response That Protects Mice against HSV-1-Induced Corneal Disease.

Davido DJ, Tu EM, Wang H, Korom M, Gazquez Casals A, Reddy PJ, Mostafa HH, Combs B, Haenchen SD, Morrison LA.

J Virol. 2018 Aug 16;92(17). pii: e01036-18. doi: 10.1128/JVI.01036-18. Print 2018 Sep 1.


Phosphatase Cdc25A Negatively Regulates the Antiviral Immune Response by Inhibiting TBK1 Activity.

Qi D, Hu L, Jiao T, Zhang T, Tong X, Ye X.

J Virol. 2018 Sep 12;92(19). pii: e01118-18. doi: 10.1128/JVI.01118-18. Print 2018 Oct 1.


SUMO Ligase Protein Inhibitor of Activated STAT1 (PIAS1) Is a Constituent Promyelocytic Leukemia Nuclear Body Protein That Contributes to the Intrinsic Antiviral Immune Response to Herpes Simplex Virus 1.

Brown JR, Conn KL, Wasson P, Charman M, Tong L, Grant K, McFarlane S, Boutell C.

J Virol. 2016 Jun 10;90(13):5939-5952. doi: 10.1128/JVI.00426-16. Print 2016 Jul 1.


Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.

Diner BA, Lum KK, Javitt A, Cristea IM.

Mol Cell Proteomics. 2015 Sep;14(9):2341-56. doi: 10.1074/mcp.M114.047068. Epub 2015 Feb 18.


Impaired STING Pathway in Human Osteosarcoma U2OS Cells Contributes to the Growth of ICP0-Null Mutant Herpes Simplex Virus.

Deschamps T, Kalamvoki M.

J Virol. 2017 Apr 13;91(9). pii: e00006-17. doi: 10.1128/JVI.00006-17. Print 2017 May 1.


Herpes Simplex Virus 1 Serine Protease VP24 Blocks the DNA-Sensing Signal Pathway by Abrogating Activation of Interferon Regulatory Factor 3.

Zhang D, Su C, Zheng C.

J Virol. 2016 May 27;90(12):5824-5829. doi: 10.1128/JVI.00186-16. Print 2016 Jun 15.


MORC3, a Component of PML Nuclear Bodies, Has a Role in Restricting Herpes Simplex Virus 1 and Human Cytomegalovirus.

Sloan E, Orr A, Everett RD.

J Virol. 2016 Sep 12;90(19):8621-33. doi: 10.1128/JVI.00621-16. Print 2016 Oct 1.


The immediate-early protein, ICP0, is essential for the resistance of herpes simplex virus to interferon-alpha/beta.

Härle P, Sainz B Jr, Carr DJ, Halford WP.

Virology. 2002 Feb 15;293(2):295-304.


Cellular Transcriptional Coactivator RanBP10 and Herpes Simplex Virus 1 ICP0 Interact and Synergistically Promote Viral Gene Expression and Replication.

Sato Y, Kato A, Maruzuru Y, Oyama M, Kozuka-Hata H, Arii J, Kawaguchi Y.

J Virol. 2016 Jan 6;90(6):3173-86. doi: 10.1128/JVI.03043-15.

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