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Items: 1 to 20 of 139

1.

Sugar-modified poly(propylene imine) dendrimers as drug delivery agents for cytarabine to overcome drug resistance.

Szulc A, Pulaski L, Appelhans D, Voit B, Klajnert-Maculewicz B.

Int J Pharm. 2016 Nov 20;513(1-2):572-583. doi: 10.1016/j.ijpharm.2016.09.063. Epub 2016 Sep 22.

PMID:
27667754
2.

Maltose modified poly(propylene imine) dendrimers as potential carriers of nucleoside analog 5'-triphosphates.

Szulc A, Signorelli M, Schiraldi A, Appelhans D, Voit B, Bryszewska M, Klajnert-Maculewicz B, Fessas D.

Int J Pharm. 2015 Nov 30;495(2):940-7. doi: 10.1016/j.ijpharm.2015.09.065. Epub 2015 Oct 9.

PMID:
26456295
3.

Effect of poly(propylene imine) glycodendrimers on β-amyloid aggregation in vitro and in APP/PS1 transgenic mice, as a model of brain amyloid deposition and Alzheimer's disease.

Klementieva O, Aso E, Filippini D, Benseny-Cases N, Carmona M, Juvés S, Appelhans D, Cladera J, Ferrer I.

Biomacromolecules. 2013 Oct 14;14(10):3570-80. doi: 10.1021/bm400948z. Epub 2013 Sep 26.

PMID:
24004423
4.

RNA expression of genes involved in cytarabine metabolism and transport predicts cytarabine response in acute myeloid leukemia.

Abraham A, Varatharajan S, Karathedath S, Philip C, Lakshmi KM, Jayavelu AK, Mohanan E, Janet NB, Srivastava VM, Shaji RV, Zhang W, Abraham A, Viswabandya A, George B, Chandy M, Srivastava A, Mathews V, Balasubramanian P.

Pharmacogenomics. 2015 Jul;16(8):877-90. doi: 10.2217/pgs.15.44. Epub 2015 Jun 17.

5.

Cytarabine-resistant leukemia cells are moderately sensitive to clofarabine in vitro.

Yamauchi T, Uzui K, Nishi R, Shigemi H, Ueda T.

Anticancer Res. 2014 Apr;34(4):1657-62.

PMID:
24692694
6.

Combination of guanine arabinoside and Bcl-2 inhibitor YC137 overcomes the cytarabine resistance in HL-60 leukemia cell line.

Nishi R, Yamauchi T, Negoro E, Takemura H, Ueda T.

Cancer Sci. 2013 Apr;104(4):502-7. doi: 10.1111/cas.12103. Epub 2013 Feb 24.

7.

Characterization of cytarabine-resistant leukemic cell lines established from five different blood cell lineages using gene expression and proteomic analyses.

Negoro E, Yamauchi T, Urasaki Y, Nishi R, Hori H, Ueda T.

Int J Oncol. 2011 Apr;38(4):911-9. doi: 10.3892/ijo.2011.933. Epub 2011 Feb 2.

PMID:
21290089
8.

Intracellular cytarabine triphosphate production correlates to deoxycytidine kinase/cytosolic 5'-nucleotidase II expression ratio in primary acute myeloid leukemia cells.

Yamauchi T, Negoro E, Kishi S, Takagi K, Yoshida A, Urasaki Y, Iwasaki H, Ueda T.

Biochem Pharmacol. 2009 Jun 15;77(12):1780-6. doi: 10.1016/j.bcp.2009.03.011. Epub 2009 Mar 24.

PMID:
19428333
9.

Toxicity and proapoptotic activity of poly(propylene imine) glycodendrimers in vitro: considering their contrary potential as biocompatible entity and drug molecule in cancer.

Ziemba B, Franiak-Pietryga I, Pion M, Appelhans D, Muñoz-Fernández MÁ, Voit B, Bryszewska M, Klajnert-Maculewicz B.

Int J Pharm. 2014 Jan 30;461(1-2):391-402. doi: 10.1016/j.ijpharm.2013.12.011. Epub 2013 Dec 17.

PMID:
24361266
10.

Sugar-Modified Poly(propylene imine) Dendrimers Stimulate the NF-κB Pathway in a Myeloid Cell Line.

Jatczak-Pawlik I, Gorzkiewicz M, Studzian M, Appelhans D, Voit B, Pulaski L, Klajnert-Maculewicz B.

Pharm Res. 2017 Jan;34(1):136-147. doi: 10.1007/s11095-016-2049-3. Epub 2016 Oct 20.

11.

Poly(propyleneimine) glycodendrimers non-covalently bind ATP in a pH- and salt-dependent manner - model studies for adenosine analogue drug delivery.

Gorzkiewicz M, Buczkowski A, Appelhans D, Voit B, Pułaski Ł, Pałecz B, Klajnert-Maculewicz B.

Int J Pharm. 2018 Jun 10;544(1):83-90. doi: 10.1016/j.ijpharm.2018.03.063. Epub 2018 Apr 10.

PMID:
29653214
12.

Fludarabine-mediated circumvention of cytarabine resistance is associated with fludarabine triphosphate accumulation in cytarabine-resistant leukemic cells.

Yamamoto S, Yamauchi T, Kawai Y, Takemura H, Kishi S, Yoshida A, Urasaki Y, Iwasaki H, Ueda T.

Int J Hematol. 2007 Feb;85(2):108-15.

PMID:
17321987
13.

Glycodendrimer Nanocarriers for Direct Delivery of Fludarabine Triphosphate to Leukemic Cells: Improved Pharmacokinetics and Pharmacodynamics of Fludarabine.

Gorzkiewicz M, Jatczak-Pawlik I, Studzian M, Pułaski Ł, Appelhans D, Voit B, Klajnert-Maculewicz B.

Biomacromolecules. 2018 Feb 12;19(2):531-543. doi: 10.1021/acs.biomac.7b01650. Epub 2018 Jan 30.

PMID:
29323872
14.

Poly(propylene imine) dendrimers modified with maltose or maltotriose protect phosphorothioate oligodeoxynucleotides against nuclease activity.

Drzewińska J, Appelhans D, Voit B, Bryszewska M, Klajnert B.

Biochem Biophys Res Commun. 2012 Oct 12;427(1):197-201. doi: 10.1016/j.bbrc.2012.09.043. Epub 2012 Sep 17.

PMID:
22995301
15.

The influence of maltotriose-modified poly(propylene imine) dendrimers on the chronic lymphocytic leukemia cells in vitro: dense shell G4 PPI.

Franiak-Pietryga I, Ziółkowska E, Ziemba B, Appelhans D, Voit B, Szewczyk M, Góra-Tybor J, Robak T, Klajnert B, Bryszewska M.

Mol Pharm. 2013 Jun 3;10(6):2490-501. doi: 10.1021/mp400142p. Epub 2013 May 16.

PMID:
23641871
16.

All-trans-retinoic acid increases cytosine arabinoside cytotoxicity in HL-60 human leukemia cells in spite of decreased cellular ara-CTP accumulation.

Freund A, Rössig C, Lanvers C, Gescher A, Hohenlöchter B, Jürgens H, Boos J.

Ann Oncol. 1999 Mar;10(3):335-8.

PMID:
10355579
17.

SAMHD1 is a biomarker for cytarabine response and a therapeutic target in acute myeloid leukemia.

Schneider C, Oellerich T, Baldauf HM, Schwarz SM, Thomas D, Flick R, Bohnenberger H, Kaderali L, Stegmann L, Cremer A, Martin M, Lohmeyer J, Michaelis M, Hornung V, Schliemann C, Berdel WE, Hartmann W, Wardelmann E, Comoglio F, Hansmann ML, Yakunin AF, Geisslinger G, Ströbel P, Ferreirós N, Serve H, Keppler OT, Cinatl J Jr.

Nat Med. 2017 Feb;23(2):250-255. doi: 10.1038/nm.4255. Epub 2016 Dec 19. Erratum in: Nat Med. 2017 Jun 6;23 (6):788.

PMID:
27991919
18.
19.

A bioluminescent microbial biosensor for in vitro pretreatment assessment of cytarabine efficacy in leukemia.

Alloush HM, Anderson E, Martin AD, Ruddock MW, Angell JE, Hill PJ, Mehta P, Smith MA, Smith JG, Salisbury VC.

Clin Chem. 2010 Dec;56(12):1862-70. doi: 10.1373/clinchem.2010.145581. Epub 2010 Oct 4.

20.

Genotoxicity of poly(propylene imine) dendrimers.

Ziemba B, Matuszko G, Appelhans D, Voit B, Bryszewska M, Klajnert B.

Biopolymers. 2012 Aug;97(8):642-8. doi: 10.1002/bip.22056.

PMID:
22605555

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