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Items: 1 to 20 of 125

1.

TRIM14 Inhibits cGAS Degradation Mediated by Selective Autophagy Receptor p62 to Promote Innate Immune Responses.

Chen M, Meng Q, Qin Y, Liang P, Tan P, He L, Zhou Y, Chen Y, Huang J, Wang RF, Cui J.

Mol Cell. 2016 Oct 6;64(1):105-119. doi: 10.1016/j.molcel.2016.08.025. Epub 2016 Sep 22.

2.

Herpes Simplex Virus 1 Tegument Protein VP22 Abrogates cGAS/STING-Mediated Antiviral Innate Immunity.

Huang J, You H, Su C, Li Y, Chen S, Zheng C.

J Virol. 2018 Jul 17;92(15). pii: e00841-18. doi: 10.1128/JVI.00841-18. Print 2018 Aug 1.

3.

Positive feedback regulation of type I IFN production by the IFN-inducible DNA sensor cGAS.

Ma F, Li B, Liu SY, Iyer SS, Yu Y, Wu A, Cheng G.

J Immunol. 2015 Feb 15;194(4):1545-54. doi: 10.4049/jimmunol.1402066. Epub 2015 Jan 21.

4.

Crosstalk between the cGAS DNA sensor and Beclin-1 autophagy protein shapes innate antimicrobial immune responses.

Liang Q, Seo GJ, Choi YJ, Kwak MJ, Ge J, Rodgers MA, Shi M, Leslie BJ, Hopfner KP, Ha T, Oh BH, Jung JU.

Cell Host Microbe. 2014 Feb 12;15(2):228-38. doi: 10.1016/j.chom.2014.01.009.

5.

Herpes Simplex Virus 1 Abrogates the cGAS/STING-Mediated Cytosolic DNA-Sensing Pathway via Its Virion Host Shutoff Protein, UL41.

Su C, Zheng C.

J Virol. 2017 Feb 28;91(6). pii: e02414-16. doi: 10.1128/JVI.02414-16. Print 2017 Mar 15.

6.

Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects.

Li XD, Wu J, Gao D, Wang H, Sun L, Chen ZJ.

Science. 2013 Sep 20;341(6152):1390-4. doi: 10.1126/science.1244040. Epub 2013 Aug 29.

7.

TRIM56-mediated monoubiquitination of cGAS for cytosolic DNA sensing.

Seo GJ, Kim C, Shin WJ, Sklan EH, Eoh H, Jung JU.

Nat Commun. 2018 Feb 9;9(1):613. doi: 10.1038/s41467-018-02936-3.

8.
9.

Human Cytomegalovirus Tegument Protein pp65 (pUL83) Dampens Type I Interferon Production by Inactivating the DNA Sensor cGAS without Affecting STING.

Biolatti M, Dell'Oste V, Pautasso S, Gugliesi F, von Einem J, Krapp C, Jakobsen MR, Borgogna C, Gariglio M, De Andrea M, Landolfo S.

J Virol. 2018 Feb 26;92(6). pii: e01774-17. doi: 10.1128/JVI.01774-17. Print 2018 Mar 15.

10.

ZCCHC3 is a co-sensor of cGAS for dsDNA recognition in innate immune response.

Lian H, Wei J, Zang R, Ye W, Yang Q, Zhang XN, Chen YD, Fu YZ, Hu MM, Lei CQ, Luo WW, Li S, Shu HB.

Nat Commun. 2018 Aug 22;9(1):3349. doi: 10.1038/s41467-018-05559-w.

11.

Autophagy side of MB21D1/cGAS DNA sensor.

Liang Q, Seo GJ, Choi YJ, Ge J, Rodgers MA, Shi M, Jung JU.

Autophagy. 2014 Jun;10(6):1146-7. doi: 10.4161/auto.28769.

12.

Attenuation of cGAS-STING signaling is mediated by a p62/SQSTM1-dependent autophagy pathway activated by TBK1.

Prabakaran T, Bodda C, Krapp C, Zhang BC, Christensen MH, Sun C, Reinert L, Cai Y, Jensen SB, Skouboe MK, Nyengaard JR, Thompson CB, Lebbink RJ, Sen GC, van Loo G, Nielsen R, Komatsu M, Nejsum LN, Jakobsen MR, Gyrd-Hansen M, Paludan SR.

EMBO J. 2018 Apr 13;37(8). pii: e97858. doi: 10.15252/embj.201797858. Epub 2018 Mar 1.

13.

Species-Specific Deamidation of cGAS by Herpes Simplex Virus UL37 Protein Facilitates Viral Replication.

Zhang J, Zhao J, Xu S, Li J, He S, Zeng Y, Xie L, Xie N, Liu T, Lee K, Seo GJ, Chen L, Stabell AC, Xia Z, Sawyer SL, Jung J, Huang C, Feng P.

Cell Host Microbe. 2018 Aug 8;24(2):234-248.e5. doi: 10.1016/j.chom.2018.07.004.

14.

The E3 ubiquitin ligase RNF185 facilitates the cGAS-mediated innate immune response.

Wang Q, Huang L, Hong Z, Lv Z, Mao Z, Tang Y, Kong X, Li S, Cui Y, Liu H, Zhang L, Zhang X, Jiang L, Wang C, Zhou Q.

PLoS Pathog. 2017 Mar 8;13(3):e1006264. doi: 10.1371/journal.ppat.1006264. eCollection 2017 Mar.

15.

USP49 negatively regulates cellular antiviral responses via deconjugating K63-linked ubiquitination of MITA.

Ye L, Zhang Q, Liuyu T, Xu Z, Zhang MX, Luo MH, Zeng WB, Zhu Q, Lin D, Zhong B.

PLoS Pathog. 2019 Apr 3;15(4):e1007680. doi: 10.1371/journal.ppat.1007680. eCollection 2019 Apr.

16.

Diminished Innate Antiviral Response to Adenovirus Vectors in cGAS/STING-Deficient Mice Minimally Impacts Adaptive Immunity.

Anghelina D, Lam E, Falck-Pedersen E.

J Virol. 2016 Jun 10;90(13):5915-27. doi: 10.1128/JVI.00500-16. Print 2016 Jul 1.

17.

Herpes Simplex Virus and Interferon Signaling Induce Novel Autophagic Clusters in Sensory Neurons.

Katzenell S, Leib DA.

J Virol. 2016 Apr 14;90(9):4706-4719. doi: 10.1128/JVI.02908-15. Print 2016 May.

18.

cGAS-mediated stabilization of IFI16 promotes innate signaling during herpes simplex virus infection.

Orzalli MH, Broekema NM, Diner BA, Hancks DC, Elde NC, Cristea IM, Knipe DM.

Proc Natl Acad Sci U S A. 2015 Apr 7;112(14):E1773-81. doi: 10.1073/pnas.1424637112. Epub 2015 Mar 23.

19.

LRRC59 modulates type I interferon signaling by restraining the SQSTM1/p62-mediated autophagic degradation of pattern recognition receptor DDX58/RIG-I.

Xian H, Yang S, Jin S, Zhang Y, Cui J.

Autophagy. 2019 May 22:1-11. doi: 10.1080/15548627.2019.1615303. [Epub ahead of print]

PMID:
31068071
20.

USP18 recruits USP20 to promote innate antiviral response through deubiquitinating STING/MITA.

Zhang M, Zhang MX, Zhang Q, Zhu GF, Yuan L, Zhang DE, Zhu Q, Yao J, Shu HB, Zhong B.

Cell Res. 2016 Dec;26(12):1302-1319. doi: 10.1038/cr.2016.125. Epub 2016 Nov 1.

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