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Items: 1 to 20 of 216

1.

Genome-wide association study on the FEV1/FVC ratio in never-smokers identifies HHIP and FAM13A.

van der Plaat DA, de Jong K, Lahousse L, Faiz A, Vonk JM, van Diemen CC, Nedeljkovic I, Amin N, Brusselle GG, Hofman A, Brandsma CA, Bossé Y, Sin DD, Nickle DC, van Duijn CM, Postma DS, Boezen HM.

J Allergy Clin Immunol. 2017 Feb;139(2):533-540. doi: 10.1016/j.jaci.2016.06.062. Epub 2016 Sep 6.

PMID:
27612410
2.

Limited overlap in significant hits between genome-wide association studies on two airflow obstruction definitions in the same population.

van der Plaat DA, Vonk JM, Lahousse L, de Jong K, Faiz A, Nedeljkovic I, Amin N, van Diemen CC, Brusselle GG, Bossé Y, Brandsma CA, Hao K, Paré PD, van Duijn CM, Postma DS, Boezen HM.

BMC Pulm Med. 2019 Mar 7;19(1):58. doi: 10.1186/s12890-019-0811-0.

3.

Identification of FAM13A gene associated with the ratio of FEV1 to FVC in Korean population by genome-wide association studies including gene-environment interactions.

Kim S, Kim H, Cho N, Lee SK, Han BG, Sull JW, Jee SH, Shin C.

J Hum Genet. 2015 Mar;60(3):139-45. doi: 10.1038/jhg.2014.118. Epub 2015 Jan 22.

PMID:
25608829
4.

Genetic Variants in the Hedgehog Interacting Protein Gene Are Associated with the FEV1/FVC Ratio in Southern Han Chinese Subjects with Chronic Obstructive Pulmonary Disease.

Zhang Z, Wang J, Zheng Z, Chen X, Zeng X, Zhang Y, Li D, Shu J, Yang K, Lai N, Dong L, Lu W.

Biomed Res Int. 2017;2017:2756726. doi: 10.1155/2017/2756726. Epub 2017 Aug 27.

5.

Gene susceptibility identification in a longitudinal study confirms new loci in the development of chronic obstructive pulmonary disease and influences lung function decline.

Xie J, Wu H, Xu Y, Wu X, Liu X, Shang J, Zhao J, Zhao J, Wang J, Dela Cruz CS, Xiong W, Xu Y.

Respir Res. 2015 Apr 18;16:49. doi: 10.1186/s12931-015-0209-3.

6.

Loci identified by genome-wide association studies influence different disease-related phenotypes in chronic obstructive pulmonary disease.

Pillai SG, Kong X, Edwards LD, Cho MH, Anderson WH, Coxson HO, Lomas DA, Silverman EK; ECLIPSE and ICGN Investigators.

Am J Respir Crit Care Med. 2010 Dec 15;182(12):1498-505. doi: 10.1164/rccm.201002-0151OC. Epub 2010 Jul 23.

7.

Genetic variants in HHIP are associated with FEV1 in subjects with chronic obstructive pulmonary disease.

Kim WJ, Oh YM, Lee JH, Park CS, Park SW, Park JS, Lee SD.

Respirology. 2013 Nov;18(8):1202-9. doi: 10.1111/resp.12139.

PMID:
23731023
8.

A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.

Lutz SM, Cho MH, Young K, Hersh CP, Castaldi PJ, McDonald ML, Regan E, Mattheisen M, DeMeo DL, Parker M, Foreman M, Make BJ, Jensen RL, Casaburi R, Lomas DA, Bhatt SP, Bakke P, Gulsvik A, Crapo JD, Beaty TH, Laird NM, Lange C, Hokanson JE, Silverman EK; ECLIPSE Investigators; COPDGene Investigators.

BMC Genet. 2015 Dec 3;16:138. doi: 10.1186/s12863-015-0299-4.

9.

Association of HHIP polymorphisms with COPD and COPD-related phenotypes in a Chinese Han population.

Wang B, Zhou H, Yang J, Xiao J, Liang B, Li D, Zhou H, Zeng Q, Fang C, Rao Z, Yu H, Ou X, Feng Y.

Gene. 2013 Nov 15;531(1):101-5. doi: 10.1016/j.gene.2013.08.069. Epub 2013 Aug 30.

PMID:
23994291
10.

Genetic variants in FAM13A and IREB2 are associated with the susceptibility to COPD in a Chinese rural population: a case-control study.

Zhang Y, Qiu J, Zhang P, Zhang J, Jiang M, Ma Z.

Int J Chron Obstruct Pulmon Dis. 2018 May 25;13:1735-1745. doi: 10.2147/COPD.S162241. eCollection 2018.

11.

Variants in multiple genes polymorphism association analysis of COPD in the Chinese Li population.

Ding Y, Yang D, Zhou L, Xu J, Chen Y, He P, Yao J, Chen J, Niu H, Sun P, Jin T.

Int J Chron Obstruct Pulmon Dis. 2015 Jul 27;10:1455-63. doi: 10.2147/COPD.S86721. eCollection 2015.

12.

Association of lung function genes with chronic obstructive pulmonary disease.

Kim WJ, Lim MN, Hong Y, Silverman EK, Lee JH, Jung BH, Ra SW, Choi HS, Jung YJ, Park YB, Park MJ, Lee SW, Lee JS, Oh YM, Lee SD.

Lung. 2014 Aug;192(4):473-80. doi: 10.1007/s00408-014-9579-4. Epub 2014 Apr 16.

PMID:
24737086
13.

CHRNA3 and CYP3A5*3 genotype, lung function and chronic obstructive pulmonary disease in the general population.

Kaur-Knudsen D, Bojesen SE, Nordestgaard BG.

Pharmacogenet Genomics. 2014 Apr;24(4):220-9. doi: 10.1097/FPC.0000000000000038.

PMID:
24535486
14.

Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank.

Wain LV, Shrine N, Miller S, Jackson VE, Ntalla I, Soler Artigas M, Billington CK, Kheirallah AK, Allen R, Cook JP, Probert K, Obeidat M, Bossé Y, Hao K, Postma DS, Paré PD, Ramasamy A; UK Brain Expression Consortium (UKBEC), Mägi R, Mihailov E, Reinmaa E, Melén E, O'Connell J, Frangou E, Delaneau O; OxGSK Consortium, Freeman C, Petkova D, McCarthy M, Sayers I, Deloukas P, Hubbard R, Pavord I, Hansell AL, Thomson NC, Zeggini E, Morris AP, Marchini J, Strachan DP, Tobin MD, Hall IP.

Lancet Respir Med. 2015 Oct;3(10):769-81. doi: 10.1016/S2213-2600(15)00283-0. Epub 2015 Sep 27. Erratum in: Lancet Respir Med. 2016 Jan;4(1):e4. Erratum in: Lancet Respir Med. 2016 Jan;4(1):e4.

15.

Genome-wide interaction study of gene-by-occupational exposure and effects on FEV1 levels.

de Jong K, Vonk JM, Timens W, Bossé Y, Sin DD, Hao K, Kromhout H, Vermeulen R, Postma DS, Boezen HM.

J Allergy Clin Immunol. 2015 Dec;136(6):1664-1672.e14. doi: 10.1016/j.jaci.2015.03.042. Epub 2015 Jun 5.

PMID:
25979521
16.

A genome-wide association study of pulmonary function measures in the Framingham Heart Study.

Wilk JB, Chen TH, Gottlieb DJ, Walter RE, Nagle MW, Brandler BJ, Myers RH, Borecki IB, Silverman EK, Weiss ST, O'Connor GT.

PLoS Genet. 2009 Mar;5(3):e1000429. doi: 10.1371/journal.pgen.1000429. Epub 2009 Mar 20.

17.

Identification of Functional Variants in the FAM13A Chronic Obstructive Pulmonary Disease Genome-Wide Association Study Locus by Massively Parallel Reporter Assays.

Castaldi PJ, Guo F, Qiao D, Du F, Naing ZZC, Li Y, Pham B, Mikkelsen TS, Cho MH, Silverman EK, Zhou X.

Am J Respir Crit Care Med. 2019 Jan 1;199(1):52-61. doi: 10.1164/rccm.201802-0337OC.

PMID:
30079747
18.

Smoking status and gene susceptibility play important roles in the development of chronic obstructive pulmonary disease and lung function decline: A population-based prospective study.

Zhao J, Li M, Chen J, Wu X, Ning Q, Zhao J, Xu Y, Xie J, Yu J.

Medicine (Baltimore). 2017 Jun;96(25):e7283. doi: 10.1097/MD.0000000000007283.

19.

A genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility loci.

Pillai SG, Ge D, Zhu G, Kong X, Shianna KV, Need AC, Feng S, Hersh CP, Bakke P, Gulsvik A, Ruppert A, Lødrup Carlsen KC, Roses A, Anderson W, Rennard SI, Lomas DA, Silverman EK, Goldstein DB; ICGN Investigators.

PLoS Genet. 2009 Mar;5(3):e1000421. doi: 10.1371/journal.pgen.1000421. Epub 2009 Mar 20.

20.

Phenotypic and genetic heterogeneity among subjects with mild airflow obstruction in COPDGene.

Lee JH, Cho MH, McDonald ML, Hersh CP, Castaldi PJ, Crapo JD, Wan ES, Dy JG, Chang Y, Regan EA, Hardin M, DeMeo DL, Silverman EK; COPDGene Investigators.

Respir Med. 2014 Oct;108(10):1469-80. doi: 10.1016/j.rmed.2014.07.018. Epub 2014 Aug 11.

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