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27604461,25024139,16140922,30124911,25743784,32617831,29272530,11359895,23505069,26321036,19129228,25153197,11555632,31611308,23570868,15805278,27537914,30830680,22558207,36184605,36265486,11555631,23049077,37003504,31181625,21769957,30060096,28760773,15805271,23813958,23434834,18558631,29463031,31350341,33810393,28082393,28843010,26931579,32012790,29197683,34993885,36122232,25678850,17308089,26055325,36759506,17935854,23343754,16585183,29145503,34145295,25740878,25416818,35588569,27841304,29197377,36747763,32217664,27452433,30226859,23814098,31836759,24719256,11196173,31835618,27585244,31427453,32291317,29494831,28755323,24709898,33600565,36153564,22250043,36513120,27183789,32916696,31846834,33597549,10362359,16806460,35385755,20071334,27295426,14499633,30690015,23185534,32669102,9175740,24698720,29542055,24531712,9467849,19339578,20042385,26158306,21914494,30788677,18708652,15287028,35328692,33450357,16820888,15767676,24074956,22348177,24523222,18311780,27405804,27452437,34492133,19901520,15805272,24996497,27154402,35159266,10964756,31837846,20454512,27090932,36399511,20655916,12507925,31905921,33595114,28135248,25593184,30615937,31171703,33479235,36265488,23717814,25330849,29569051,36350851,31405990,19237542,30010917,11948462,19180191,27083540,27411289,22547822,25175359,30716077,20016274,32183119,21822009,33673424,23759591,22110753,32109830,29534204,22922742,36980890,22952882,19850908,23276906,24842907,20861676,21289002,31127568,27578458,31650883,22829774,23219603,27892716,28440422,27779655,33128602,27530378,9618172,24014600,15577208,28666126,27531349,28521363,8757195,31837325,27932441,22266933,30673617,29059385,27871469,19442255,28151936,23547895,19214183,34432566,25047690,23644601,24792489,28002788,33371452,30118998,28673972,31062416,22719262,30475094,29290038,12757973,19684619,29167439,31128432,28398700,12814799,32792055,31713610,32379321,29848621,23229897,28765174,33841503,32084415,21888887,23326560,30824709,21037079,28535013,18562689,29718321,31038385,11384704,24500201,24758186,11121234,19629047,33217925,37105990,28969871,32061930,28425984,27697227,23260199,34488828,29749098,33127860,35790854,27836977,24339742,33413203,29602239,27977688,30270279,29956721,11082050,33411257,33453166,22545052,29351238,21131778,33244044,36991019,37046839,11823034,30026266,28514537,29670078,24278232,29108468,32588833,31322481,32333143,27391261,33820871,9359704,29392401,29658398,28973513,33242406,29273061,22947336,30771304,32916703,19363487,35188570,19015236,21277646,33663806,24225324,32163830,20460456,32117990,33389530,30474505,23450006,18414473,33639094,36805596,36908640,35430275,20364118,32674474,35707279,30423030,27918544,23770704,32579791,31510074,27768860,33293233,28817493,32579423,32560940,30735171,22832159,35259951,34486664,35484160,21866390,24882549,27583462,19617716,21763260,30922639,23935072,27185864,35953846,26382656,27474163,31336873,31526614,28161061,30709063,17485108,28716051,35830448,24413054,14555494,23114548,32035903,34112789,29167542,28666128,24828261,15059879,25926849,15974880,22572954,22184006,26502804,31357948,32114293,30785764,22516689,35947641,24821186,32114294,33211388,29112847,10744686,16339074,28678605,24996384,20962020,34771533,30760384,17916692,19359039,34136834,11712758,31248154,24334955,11571635,32860669,32900359,28412741,32226245,19095716,21512205,22925423,33530025,22848311,36923475,23133400,30811824,8498447,19935656,30208911,32375866,22032438,22641694,18239859,33057192,24927411,30779012,31273310,11200816,22425786,33806168,24550456,26190020,31265183,29169400,34486523,28098215,30833786,22923525,31974116,29235471,30212832,29776332,30407559,29040510,19106645,28223336,19858100,24759919,14618159,36979904,21441915,19223605,32959123,33852895,8924503,17959650,29108638,36332602,35006465,31284662,10500096,32971118,29722072,31278054,24161135,28500256,33627664,25084169,24563217,19211845,35942347,30687384,17982445,9357546,30517099,31064004,29084850,32203094,30309499,27026712,29649255,28636941,23307865,22315652,30870992,30875900,19137021,30223723,27872149,28375735,32331249,21187328,21619941,32337843,30371886,21474991,22371573,12220625,23530188,33664422,32016800,37024489,30788057,31447390,31550289,20975687,24375252,29069086,29513567,33581499,11514058,33669975,10820249,26911255,26132175,29870526,31115790,28674422,19586922,30732639,27958374,29216888,31903880,33567726,26970083,35682861,31425705,34316718,36140400,11470873,25874893,24051140,21222203,20017721,19468068,19766308,36860927,32468444,31924155,25801836,28834755,36689342,35061898,36011306,32319609,21268042,32619492,22661914,33344901,31138795,25464850,23066103,35704191,32708387,14763510,23716593,28900814,31157162,24098638,34021146,23921659,35359323,24986269,34426596,32175073,35979662,30696885,28792463,21549308,27666406,16789902,27595911,15601583,14672427,28854735,20351727,24074950,35147992,33548324,31012504,34205622,29335378,22792358,28234020,33256840,10721008,29637701,31462295,29335373,33082350,22848298,30862510,29240300,9683783,35155512,29668072,31350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75163,28924259,29378826,29677331[uid]

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DNA methylation mediated up-regulation of TERRA non-coding RNA is coincident with elongated telomeres in the human placenta.

Novakovic B, Napier CE, Vryer R, Dimitriadis E, Manuelpillai U, Sharkey A, Craig JM, Reddel RR, Saffery R. Novakovic B, et al. Mol Hum Reprod. 2016 Nov;22(11):791-799. doi: 10.1093/molehr/gaw053. Epub 2016 Sep 7. Mol Hum Reprod. 2016. PMID: 27604461

Epigenetic mechanisms regulate placental c-myc and hTERT in normal and pathological pregnancies; c-myc as a novel fetal DNA epigenetic marker for pre-eclampsia.

Rahat B, Hamid A, Ahmad Najar R, Bagga R, Kaur J. Rahat B, et al. Mol Hum Reprod. 2014 Oct;20(10):1026-40. doi: 10.1093/molehr/gau053. Epub 2014 Jul 14. Mol Hum Reprod. 2014. PMID: 25024139

Lack of telomerase gene expression in alternative lengthening of telomere cells is associated with chromatin remodeling of the hTR and hTERT gene promoters.

Atkinson SP, Hoare SF, Glasspool RM, Keith WN. Atkinson SP, et al. Cancer Res. 2005 Sep 1;65(17):7585-90. doi: 10.1158/0008-5472.CAN-05-1715. Cancer Res. 2005. PMID: 16140922

ADAM8 localizes to extravillous trophoblasts within the maternal-fetal interface and potentiates trophoblast cell line migration through a β1 integrin-mediated mechanism.

Le HT, Atif J, Mara DL, Castellana B, Treissman J, Baltayeva J, Beristain AG. Le HT, et al. Mol Hum Reprod. 2018 Oct 1;24(10):495-509. doi: 10.1093/molehr/gay034. Mol Hum Reprod. 2018. PMID: 30124911 Free PMC article.

Dynamic changes in hyperglycosylated human chorionic gonadotrophin throughout the first trimester of pregnancy and its role in early placentation.

Evans J, Salamonsen LA, Menkhorst E, Dimitriadis E. Evans J, et al. Hum Reprod. 2015 May;30(5):1029-38. doi: 10.1093/humrep/dev016. Epub 2015 Mar 4. Hum Reprod. 2015. PMID: 25743784

DNA Methylation Profiling of hTERT Gene Alongside with the Telomere Performance in Gastric Adenocarcinoma.

Vahidi S, Norollahi SE, Agah S, Samadani AA. Vahidi S, et al. J Gastrointest Cancer. 2020 Sep;51(3):788-799. doi: 10.1007/s12029-020-00427-7. J Gastrointest Cancer. 2020. PMID: 32617831 Review.

Formyl peptide receptor-2 is decreased in foetal growth restriction and contributes to placental dysfunction.

Lappas M, McCracken S, McKelvey K, Lim R, James J, Roberts CT, Fournier T, Alfaidy N, Powell KL, Borg AJ, Morris JM, Leaw B, Singh H, Ebeling PR, Wallace EM, Parry LJ, Dimitriadis E, Murthi P. Lappas M, et al. Mol Hum Reprod. 2018 Feb 1;24(2):94-109. doi: 10.1093/molehr/gax067. Mol Hum Reprod. 2018. PMID: 29272530

Coexistence of alternative lengthening of telomeres and telomerase in hTERT-transfected GM847 cells.

Perrem K, Colgin LM, Neumann AA, Yeager TR, Reddel RR. Perrem K, et al. Mol Cell Biol. 2001 Jun;21(12):3862-75. doi: 10.1128/MCB.21.12.3862-3875.2001. Mol Cell Biol. 2001. PMID: 11359895 Free PMC article.

Telomerase suppresses formation of ALT-associated single-stranded telomeric C-circles.

Plantinga MJ, Pascarelli KM, Merkel AS, Lazar AJ, von Mehren M, Lev D, Broccoli D. Plantinga MJ, et al. Mol Cancer Res. 2013 Jun;11(6):557-67. doi: 10.1158/1541-7786.MCR-13-0013. Epub 2013 Mar 15. Mol Cancer Res. 2013. PMID: 23505069

Telomere homeostasis in trophoblasts and in cord blood cells from pregnancies complicated with preeclampsia.

Sukenik-Halevy R, Amiel A, Kidron D, Liberman M, Ganor-Paz Y, Biron-Shental T. Sukenik-Halevy R, et al. Am J Obstet Gynecol. 2016 Feb;214(2):283.e1-283.e7. doi: 10.1016/j.ajog.2015.08.050. Epub 2015 Aug 28. Am J Obstet Gynecol. 2016. PMID: 26321036

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