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Items: 1 to 20 of 102

1.

Proteomic Interaction Patterns between Human Cyclins, the Cyclin-Dependent Kinase Ortholog pUL97 and Additional Cytomegalovirus Proteins.

Steingruber M, Kraut A, Socher E, Sticht H, Reichel A, Stamminger T, Amin B, Couté Y, Hutterer C, Marschall M.

Viruses. 2016 Aug 18;8(8). pii: E219. doi: 10.3390/v8080219.

2.

The cyclin-dependent kinase ortholog pUL97 of human cytomegalovirus interacts with cyclins.

Graf L, Webel R, Wagner S, Hamilton ST, Rawlinson WD, Sticht H, Marschall M.

Viruses. 2013 Dec 18;5(12):3213-30. doi: 10.3390/v5123213.

3.

The Interaction between Cyclin B1 and Cytomegalovirus Protein Kinase pUL97 is Determined by an Active Kinase Domain.

Steingruber M, Socher E, Hutterer C, Webel R, Bergbrede T, Lenac T, Sticht H, Marschall M.

Viruses. 2015 Aug 11;7(8):4582-601. doi: 10.3390/v7082834.

4.

Antagonistic Relationship between Human Cytomegalovirus pUL27 and pUL97 Activities during Infection.

Bigley TM, Reitsma JM, Terhune SS.

J Virol. 2015 Oct;89(20):10230-46. doi: 10.1128/JVI.00986-15. Epub 2015 Jul 29.

5.

Regulatory roles of protein kinases in cytomegalovirus replication.

Marschall M, Feichtinger S, Milbradt J.

Adv Virus Res. 2011;80:69-101. doi: 10.1016/B978-0-12-385987-7.00004-X. Review.

PMID:
21762822
6.

Cyclin-dependent Kinases Phosphorylate the Cytomegalovirus RNA Export Protein pUL69 and Modulate Its Nuclear Localization and Activity.

Rechter S, Scott GM, Eickhoff J, Zielke K, Auerochs S, Müller R, Stamminger T, Rawlinson WD, Marschall M.

J Biol Chem. 2009 Mar 27;284(13):8605-13. doi: 10.1074/jbc.M805693200. Epub 2009 Jan 29.

7.

Human cytomegalovirus pUL97 kinase induces global changes in the infected cell phosphoproteome.

Oberstein A, Perlman DH, Shenk T, Terry LJ.

Proteomics. 2015 Jun;15(12):2006-22. doi: 10.1002/pmic.201400607. Epub 2015 May 12.

8.

Protein kinases responsible for the phosphorylation of the nuclear egress core complex of human cytomegalovirus.

Sonntag E, Milbradt J, Svrlanska A, Strojan H, Häge S, Kraut A, Hesse AM, Amin B, Sonnewald U, Couté Y, Marschall M.

J Gen Virol. 2017 Oct;98(10):2569-2581. doi: 10.1099/jgv.0.000931. Epub 2017 Sep 27.

PMID:
28949903
9.

Human cytomegalovirus pUL97 regulates the viral major immediate early promoter by phosphorylation-mediated disruption of histone deacetylase 1 binding.

Bigley TM, Reitsma JM, Mirza SP, Terhune SS.

J Virol. 2013 Jul;87(13):7393-408. doi: 10.1128/JVI.02825-12. Epub 2013 Apr 24.

10.

Constitutively active K-cyclin/cdk6 kinase in Kaposi sarcoma-associated herpesvirus-infected cells.

Van Dross R, Yao S, Asad S, Westlake G, Mays DJ, Barquero L, Duell S, Pietenpol JA, Browning PJ.

J Natl Cancer Inst. 2005 May 4;97(9):656-66.

PMID:
15870436
11.

New insight into the phosphorylation-regulated intranuclear localization of human cytomegalovirus pUL69 mediated by cyclin-dependent kinases (CDKs) and viral CDK orthologue pUL97.

Graf L, Feichtinger S, Naing Z, Hutterer C, Milbradt J, Webel R, Wagner S, Scott GM, Hamilton ST, Rawlinson WD, Stamminger T, Thomas M, Marschall M.

J Gen Virol. 2016 Jan;97(1):144-51. doi: 10.1099/jgv.0.000337. Epub 2015 Nov 6.

PMID:
26555090
12.

Characterization of murine gammaherpesvirus 68 v-cyclin interactions with cellular cdks.

Upton JW, van Dyk LF, Speck SH.

Virology. 2005 Oct 25;341(2):271-83. Epub 2005 Aug 15.

13.

Differential properties of cytomegalovirus pUL97 kinase isoforms affect viral replication and maribavir susceptibility.

Webel R, Hakki M, Prichard MN, Rawlinson WD, Marschall M, Chou S.

J Virol. 2014 May;88(9):4776-85. doi: 10.1128/JVI.00192-14. Epub 2014 Feb 12.

14.

Human cytomegalovirus tegument protein pp150 acts as a cyclin A2-CDK-dependent sensor of the host cell cycle and differentiation state.

Bogdanow B, Weisbach H, von Einem J, Straschewski S, Voigt S, Winkler M, Hagemeier C, Wiebusch L.

Proc Natl Acad Sci U S A. 2013 Oct 22;110(43):17510-5. doi: 10.1073/pnas.1312235110. Epub 2013 Oct 7.

15.

Novel mode of phosphorylation-triggered reorganization of the nuclear lamina during nuclear egress of human cytomegalovirus.

Milbradt J, Webel R, Auerochs S, Sticht H, Marschall M.

J Biol Chem. 2010 Apr 30;285(18):13979-89. doi: 10.1074/jbc.M109.063628. Epub 2010 Mar 4.

17.

Dynamic regulatory interaction between cytomegalovirus major tegument protein pp65 and protein kinase pUL97 in intracellular compartments, dense bodies and virions.

König P, Büscher N, Steingruber M, Socher E, Sticht H, Tenzer S, Plachter B, Marschall M.

J Gen Virol. 2017 Nov;98(11):2850-2863. doi: 10.1099/jgv.0.000939. Epub 2017 Oct 12.

PMID:
29022869
18.

Modification of the major tegument protein pp65 of human cytomegalovirus inhibits virus growth and leads to the enhancement of a protein complex with pUL69 and pUL97 in infected cells.

Becke S, Fabre-Mersseman V, Aue S, Auerochs S, Sedmak T, Wolfrum U, Strand D, Marschall M, Plachter B, Reyda S.

J Gen Virol. 2010 Oct;91(Pt 10):2531-41. doi: 10.1099/vir.0.022293-0. Epub 2010 Jun 30.

PMID:
20592110
19.
20.

Antiviral inhibition targeting the HCMV kinase pUL97 requires pUL27-dependent degradation of Tip60 acetyltransferase and cell-cycle arrest.

Reitsma JM, Savaryn JP, Faust K, Sato H, Halligan BD, Terhune SS.

Cell Host Microbe. 2011 Feb 17;9(2):103-14. doi: 10.1016/j.chom.2011.01.006.

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