Similar articles for PMID: 27517620

Year	Number of Results
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1

Inhibition of glucosylceramide synthase eliminates the oncogenic function of p53 R273H mutant in the epithelial-mesenchymal transition and induced pluripotency of colon cancer cells.

Hosain SB, Khiste SK, Uddin MB, Vorubindi V, Ingram C, Zhang S, Hill RA, Gu X, Liu YY. Hosain SB, et al. Oncotarget. 2016 Sep 13;7(37):60575-60592. doi: 10.18632/oncotarget.11169. Oncotarget. 2016. PMID: 27517620 Free PMC article.

2

An N⁶-methyladenosine at the transited codon 273 of p53 pre-mRNA promotes the expression of R273H mutant protein and drug resistance of cancer cells.

Uddin MB, Roy KR, Hosain SB, Khiste SK, Hill RA, Jois SD, Zhao Y, Tackett AJ, Liu YY. Uddin MB, et al. Biochem Pharmacol. 2019 Feb;160:134-145. doi: 10.1016/j.bcp.2018.12.014. Epub 2018 Dec 19. Biochem Pharmacol. 2019. PMID: 30578766 Free PMC article.

3

P53-R273H mutation enhances colorectal cancer stemness through regulating specific lncRNAs.

Zhao Y, Li Y, Sheng J, Wu F, Li K, Huang R, Wang X, Jiao T, Guan X, Lu Y, Chen X, Luo Z, Zhou Y, Hu H, Liu W, Du B, Miao S, Cai J, Wang L, Zhao H, Ying J, Bi X, Song W. Zhao Y, et al. J Exp Clin Cancer Res. 2019 Aug 28;38(1):379. doi: 10.1186/s13046-019-1375-9. J Exp Clin Cancer Res. 2019. PMID: 31455383 Free PMC article.

4

Gb3-cSrc complex in glycosphingolipid-enriched microdomains contributes to the expression of p53 mutant protein and cancer drug resistance via β-catenin-activated RNA methylation.

Roy KR, Uddin MB, Roy SC, Hill RA, Marshall J, Li YT, Chamcheu JC, Lu H, Liu YY. Roy KR, et al. FASEB Bioadv. 2020 Sep 2;2(11):653-667. doi: 10.1096/fba.2020-00044. eCollection 2020 Nov. FASEB Bioadv. 2020. PMID: 33205006 Free PMC article.

5

Suppression of glucosylceramide synthase restores p53-dependent apoptosis in mutant p53 cancer cells.

Liu YY, Patwardhan GA, Bhinge K, Gupta V, Gu X, Jazwinski SM. Liu YY, et al. Cancer Res. 2011 Mar 15;71(6):2276-85. doi: 10.1158/0008-5472.CAN-10-3107. Epub 2011 Jan 28. Cancer Res. 2011. PMID: 21278235 Free PMC article.

6

DNA damage-induced ephrin-B2 reverse signaling promotes chemoresistance and drives EMT in colorectal carcinoma harboring mutant p53.

Alam SK, Yadav VK, Bajaj S, Datta A, Dutta SK, Bhattacharyya M, Bhattacharya S, Debnath S, Roy S, Boardman LA, Smyrk TC, Molina JR, Chakrabarti S, Chowdhury S, Mukhopadhyay D, Roychoudhury S. Alam SK, et al. Cell Death Differ. 2016 Apr;23(4):707-22. doi: 10.1038/cdd.2015.133. Epub 2015 Oct 23. Cell Death Differ. 2016. PMID: 26494468 Free PMC article.

7

Mutant p53-R273H mediates cancer cell survival and anoikis resistance through AKT-dependent suppression of BCL2-modifying factor (BMF).

Tan BS, Tiong KH, Choo HL, Chung FF, Hii LW, Tan SH, Yap IK, Pani S, Khor NT, Wong SF, Rosli R, Cheong SK, Leong CO. Tan BS, et al. Cell Death Dis. 2015 Jul 16;6(7):e1826. doi: 10.1038/cddis.2015.191. Cell Death Dis. 2015. PMID: 26181206 Free PMC article.

8

Trp53 null and R270H mutant alleles have comparable effects in regulating invasion, metastasis, and gene expression in mouse colon tumorigenesis.

Tang J, Feng Y, Kuick R, Green M, Green M, Sakamoto N, Kurosu Y, Lin J, Cho KR, Fearon ER. Tang J, et al. Lab Invest. 2019 Oct;99(10):1454-1469. doi: 10.1038/s41374-019-0269-y. Epub 2019 May 31. Lab Invest. 2019. PMID: 31148594 Free PMC article.

9

Mutant p53 in colon cancer.

Nakayama M, Oshima M. Nakayama M, et al. J Mol Cell Biol. 2019 Apr 1;11(4):267-276. doi: 10.1093/jmcb/mjy075. J Mol Cell Biol. 2019. PMID: 30496442 Free PMC article. Review.

10

Mutant p53 gain of function underlies high expression levels of colorectal cancer stem cells markers.

Solomon H, Dinowitz N, Pateras IS, Cooks T, Shetzer Y, Molchadsky A, Charni M, Rabani S, Koifman G, Tarcic O, Porat Z, Kogan-Sakin I, Goldfinger N, Oren M, Harris CC, Gorgoulis VG, Rotter V. Solomon H, et al. Oncogene. 2018 Mar;37(12):1669-1684. doi: 10.1038/s41388-017-0060-8. Epub 2018 Jan 18. Oncogene. 2018. PMID: 29343849 Free PMC article.

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