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Items: 1 to 20 of 95

1.

Cytosolic Ku70 regulates Bax-mediated cell death.

Hada M, Subramanian C, Andrews PC, Kwok RP.

Tumour Biol. 2016 Oct;37(10):13903-13914. Epub 2016 Aug 3.

2.

HDAC6 deacetylates Ku70 and regulates Ku70-Bax binding in neuroblastoma.

Subramanian C, Jarzembowski JA, Opipari AW Jr, Castle VP, Kwok RP.

Neoplasia. 2011 Aug;13(8):726-34.

3.

CREB-binding protein is a mediator of neuroblastoma cell death induced by the histone deacetylase inhibitor trichostatin A.

Subramanian C, Jarzembowski JA, Opipari AW Jr, Castle VP, Kwok RP.

Neoplasia. 2007 Jun;9(6):495-503.

4.

CLU blocks HDACI-mediated killing of neuroblastoma.

Subramanian C, Jarzembowski JA, Halsey SM, Kuick R, Opipari AW Jr, Castle VP, Kwok RP.

Tumour Biol. 2011 Apr;32(2):285-94. doi: 10.1007/s13277-010-0120-y. Epub 2010 Nov 2.

5.

CREB-binding protein regulates Ku70 acetylation in response to ionization radiation in neuroblastoma.

Subramanian C, Hada M, Opipari AW Jr, Castle VP, Kwok RP.

Mol Cancer Res. 2013 Feb;11(2):173-81. doi: 10.1158/1541-7786.MCR-12-0065. Epub 2012 Dec 5.

6.

Ku70 acetylation mediates neuroblastoma cell death induced by histone deacetylase inhibitors.

Subramanian C, Opipari AW Jr, Bian X, Castle VP, Kwok RP.

Proc Natl Acad Sci U S A. 2005 Mar 29;102(13):4842-7. Epub 2005 Mar 18.

7.

EGCG induces lung cancer A549 cell apoptosis by regulating Ku70 acetylation.

Li M, Li JJ, Gu QH, An J, Cao LM, Yang HP, Hu CP.

Oncol Rep. 2016 Apr;35(4):2339-47. doi: 10.3892/or.2016.4587. Epub 2016 Jan 21.

PMID:
26794417
8.

Deacetylation of Ku70 by SIRT6 attenuates Bax-mediated apoptosis in hepatocellular carcinoma.

Tao NN, Ren JH, Tang H, Ran LK, Zhou HZ, Liu B, Huang AL, Chen J.

Biochem Biophys Res Commun. 2017 Apr 15;485(4):713-719. doi: 10.1016/j.bbrc.2017.02.111. Epub 2017 Feb 24.

PMID:
28238784
9.

Maspin increases Ku70 acetylation and Bax-mediated cell death in cancer cells.

Lee SJ, Jang H, Park C.

Int J Mol Med. 2012 Feb;29(2):225-30. doi: 10.3892/ijmm.2011.833. Epub 2011 Nov 10.

PMID:
22076034
10.

Intracellular clusterin inhibits mitochondrial apoptosis by suppressing p53-activating stress signals and stabilizing the cytosolic Ku70-Bax protein complex.

Trougakos IP, Lourda M, Antonelou MH, Kletsas D, Gorgoulis VG, Papassideri IS, Zou Y, Margaritis LH, Boothman DA, Gonos ES.

Clin Cancer Res. 2009 Jan 1;15(1):48-59. doi: 10.1158/1078-0432.CCR-08-1805.

11.

Interaction of caveolin-1 with Ku70 inhibits Bax-mediated apoptosis.

Zou H, Volonte D, Galbiati F.

PLoS One. 2012;7(6):e39379. doi: 10.1371/journal.pone.0039379. Epub 2012 Jun 20. Erratum in: PLoS One. doi: 10.1371/annotation/83804d5a-9c9b-4b9a-9aa3-cb6da8a78fe9.

12.

Hdm2 is a ubiquitin ligase of Ku70-Akt promotes cell survival by inhibiting Hdm2-dependent Ku70 destabilization.

Gama V, Gomez JA, Mayo LD, Jackson MW, Danielpour D, Song K, Haas AL, Laughlin MJ, Matsuyama S.

Cell Death Differ. 2009 May;16(5):758-69. doi: 10.1038/cdd.2009.6. Epub 2009 Feb 27.

13.

Histone deacetylase inhibitors sensitize lung cancer cells to hyperthermia: involvement of Ku70/SirT-1 in thermo-protection.

Hassan MK, Watari H, Salah-Eldin AE, Sultan AS, Mohamed Z, Fujioka Y, Ohba Y, Sakuragi N.

PLoS One. 2014 Apr 11;9(4):e94213. doi: 10.1371/journal.pone.0094213. eCollection 2014.

14.

Regulation of ku70-bax complex in cells.

Hada M, Kwok RP.

J Cell Death. 2014 Feb 13;7:11-3. doi: 10.4137/JCD.S13695. eCollection 2014.

15.

Ku70 is essential for histone deacetylase inhibitor trichostatin A-induced apoptosis.

Meng J, Zhang F, Zhang XT, Zhang T, Li YH, Fan L, Sun Y, Zhang HL, Mei QB.

Mol Med Rep. 2015 Jul;12(1):581-6. doi: 10.3892/mmr.2015.3358. Epub 2015 Feb 16.

PMID:
25695595
16.

Oxidative stress induces nuclear loss of DNA repair proteins Ku70 and Ku80 and apoptosis in pancreatic acinar AR42J cells.

Song JY, Lim JW, Kim H, Morio T, Kim KH.

J Biol Chem. 2003 Sep 19;278(38):36676-87. Epub 2003 Jul 16.

17.

Interleukin-6 affects cell death escaping mechanisms acting on Bax-Ku70-Clusterin interactions in human colon cancer progression.

Pucci S, Mazzarelli P, Sesti F, Boothman DA, Spagnoli LG.

Cell Cycle. 2009 Feb 1;8(3):473-81. Epub 2009 Feb 18. Erratum in: Cell Cycle. 2009 Jul 15;8(14):2305. Paola, Mazzarelli [corrected to Mazzarelli, Paola]; Fabiola, Sesti [corrected to Sesti, Fabiola]; David, Boothman A [corrected to Boothman, David A]; Luigi, Spagnoli G [corrected to Spagnoli, Luigi G].

18.

The PI3K/AKT pathway promotes gefitinib resistance in mutant KRAS lung adenocarcinoma by a deacetylase-dependent mechanism.

Jeannot V, Busser B, Brambilla E, Wislez M, Robin B, Cadranel J, Coll JL, Hurbin A.

Int J Cancer. 2014 Jun 1;134(11):2560-71. doi: 10.1002/ijc.28594. Epub 2013 Dec 13.

19.

Interaction of a cyclin E fragment with Ku70 regulates Bax-mediated apoptosis.

Mazumder S, Plesca D, Kinter M, Almasan A.

Mol Cell Biol. 2007 May;27(9):3511-20. Epub 2007 Feb 26.

20.

The DNA-PK catalytic subunit regulates Bax-mediated excitotoxic cell death by Ku70 phosphorylation.

Liu J, Naegele JR, Lin SL.

Brain Res. 2009 Nov 3;1296:164-75. doi: 10.1016/j.brainres.2009.07.101. Epub 2009 Aug 4.

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