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Items: 1 to 20 of 115

1.

Pyruvate dehydrogenase kinase regulates hepatitis C virus replication.

Jung GS, Jeon JH, Choi YK, Jang SY, Park SY, Kim SW, Byun JK, Kim MK, Lee S, Shin EC, Lee IK, Kang YN, Park KG.

Sci Rep. 2016 Jul 29;6:30846. doi: 10.1038/srep30846.

2.

Targeting Hypoxia-Inducible Factor-1α/Pyruvate Dehydrogenase Kinase 1 Axis by Dichloroacetate Suppresses Bleomycin-induced Pulmonary Fibrosis.

Goodwin J, Choi H, Hsieh MH, Neugent ML, Ahn JM, Hayenga HN, Singh PK, Shackelford DB, Lee IK, Shulaev V, Dhar S, Takeda N, Kim JW.

Am J Respir Cell Mol Biol. 2018 Feb;58(2):216-231. doi: 10.1165/rcmb.2016-0186OC.

3.

Low oxygen tension enhances hepatitis C virus replication.

Vassilaki N, Kalliampakou KI, Kotta-Loizou I, Befani C, Liakos P, Simos G, Mentis AF, Kalliaropoulos A, Doumba PP, Smirlis D, Foka P, Bauhofer O, Poenisch M, Windisch MP, Lee ME, Koskinas J, Bartenschlager R, Mavromara P.

J Virol. 2013 Mar;87(5):2935-48. doi: 10.1128/JVI.02534-12. Epub 2012 Dec 26.

4.

Inactivation of the HIF-1α/PDK3 signaling axis drives melanoma toward mitochondrial oxidative metabolism and potentiates the therapeutic activity of pro-oxidants.

Kluza J, Corazao-Rozas P, Touil Y, Jendoubi M, Maire C, Guerreschi P, Jonneaux A, Ballot C, Balayssac S, Valable S, Corroyer-Dulmont A, Bernaudin M, Malet-Martino M, de Lassalle EM, Maboudou P, Formstecher P, Polakowska R, Mortier L, Marchetti P.

Cancer Res. 2012 Oct 1;72(19):5035-47. doi: 10.1158/0008-5472.CAN-12-0979. Epub 2012 Aug 3.

5.

Nonstructural 3 Protein of Hepatitis C Virus Modulates the Tribbles Homolog 3/Akt Signaling Pathway for Persistent Viral Infection.

Tran SC, Pham TM, Nguyen LN, Park EM, Lim YS, Hwang SB.

J Virol. 2016 Jul 27;90(16):7231-7247. doi: 10.1128/JVI.00326-16. Print 2016 Aug 15.

6.

N-Myc Downstream-Regulated Gene 1 Restricts Hepatitis C Virus Propagation by Regulating Lipid Droplet Biogenesis and Viral Assembly.

Schweitzer CJ, Zhang F, Boyer A, Valdez K, Cam M, Liang TJ.

J Virol. 2018 Jan 2;92(2). pii: e01166-17. doi: 10.1128/JVI.01166-17. Print 2018 Jan 15.

7.

Expression of pyruvate dehydrogenase kinase-1 in gastric cancer as a potential therapeutic target.

Hur H, Xuan Y, Kim YB, Lee G, Shim W, Yun J, Ham IH, Han SU.

Int J Oncol. 2013 Jan;42(1):44-54. doi: 10.3892/ijo.2012.1687. Epub 2012 Nov 6.

8.

Ribavirin enhances the action of interferon-α against hepatitis C virus by promoting the p53 activity through the ERK1/2 pathway.

Liu WL, Yang HC, Su WC, Wang CC, Chen HL, Wang HY, Huang WH, Chen DS, Lai MY.

PLoS One. 2012;7(9):e43824. doi: 10.1371/journal.pone.0043824. Epub 2012 Sep 4.

9.

Effect of ethanol on innate antiviral pathways and HCV replication in human liver cells.

Plumlee CR, Lazaro CA, Fausto N, Polyak SJ.

Virol J. 2005 Dec 2;2:89.

10.

Bile acids promote the expression of hepatitis C virus in replicon-harboring cells.

Chang KO, George DW.

J Virol. 2007 Sep;81(18):9633-40. Epub 2007 Jul 3.

11.

The AMPK-related kinase SNARK regulates hepatitis C virus replication and pathogenesis through enhancement of TGF-β signaling.

Goto K, Lin W, Zhang L, Jilg N, Shao RX, Schaefer EA, Zhao H, Fusco DN, Peng LF, Kato N, Chung RT.

J Hepatol. 2013 Nov;59(5):942-8. doi: 10.1016/j.jhep.2013.06.025. Epub 2013 Jul 2.

12.

Targeting cellular squalene synthase, an enzyme essential for cholesterol biosynthesis, is a potential antiviral strategy against hepatitis C virus.

Saito K, Shirasago Y, Suzuki T, Aizaki H, Hanada K, Wakita T, Nishijima M, Fukasawa M.

J Virol. 2015 Feb;89(4):2220-32. doi: 10.1128/JVI.03385-14. Epub 2014 Dec 3.

13.

MicroRNA let-7g cooperates with interferon/ribavirin to repress hepatitis C virus replication.

Chou WW, Huang CF, Yeh ML, Tsai YS, Hsieh MY, Huang CI, Huang JF, Tsai PC, Hsi E, Juo SH, Tsai WL, Chuang WL, Yu ML, Dai CY.

J Mol Med (Berl). 2016 Mar;94(3):311-20. doi: 10.1007/s00109-015-1348-1. Epub 2015 Oct 21.

PMID:
26489607
14.

Mutual antagonism between circadian protein period 2 and hepatitis C virus replication in hepatocytes.

Benegiamo G, Mazzoccoli G, Cappello F, Rappa F, Scibetta N, Oben J, Greco A, Williams R, Andriulli A, Vinciguerra M, Pazienza V.

PLoS One. 2013 Apr 8;8(4):e60527. doi: 10.1371/journal.pone.0060527. Print 2013.

15.

Endocannabinoid system activation contributes to glucose metabolism disorders of hepatocytes and promotes hepatitis C virus replication.

Sun LJ, Yu JW, Wan L, Zhang XY, Shi YG, Chen MY.

Int J Infect Dis. 2014 Jun;23:75-81. doi: 10.1016/j.ijid.2013.12.017. Epub 2014 Apr 2.

16.

Class A scavenger receptor 1 (MSR1) restricts hepatitis C virus replication by mediating toll-like receptor 3 recognition of viral RNAs produced in neighboring cells.

Dansako H, Yamane D, Welsch C, McGivern DR, Hu F, Kato N, Lemon SM.

PLoS Pathog. 2013;9(5):e1003345. doi: 10.1371/journal.ppat.1003345. Epub 2013 May 23.

17.

Identification of three interferon-inducible cellular enzymes that inhibit the replication of hepatitis C virus.

Jiang D, Guo H, Xu C, Chang J, Gu B, Wang L, Block TM, Guo JT.

J Virol. 2008 Feb;82(4):1665-78. Epub 2007 Dec 12.

18.

HCV replication suppresses cellular glucose uptake through down-regulation of cell surface expression of glucose transporters.

Kasai D, Adachi T, Deng L, Nagano-Fujii M, Sada K, Ikeda M, Kato N, Ide YH, Shoji I, Hotta H.

J Hepatol. 2009 May;50(5):883-94. doi: 10.1016/j.jhep.2008.12.029. Epub 2009 Feb 27.

PMID:
19303158
19.

Hepatitis C virus RNA kinetics: drug efficacy and the rate of HCV-infected cells loss.

Dahari H, Perelson AS.

World J Gastroenterol. 2007 Jun 7;13(21):3020-1. No abstract available.

20.

Pegylated IFN-α suppresses hepatitis C virus by promoting the DAPK-mTOR pathway.

Liu WL, Yang HC, Hsu CS, Wang CC, Wang TS, Kao JH, Chen DS.

Proc Natl Acad Sci U S A. 2016 Dec 20;113(51):14799-14804. doi: 10.1073/pnas.1618517114. Epub 2016 Dec 6.

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