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Items: 1 to 20 of 88

1.

Decreased Usage of Specific Scrib Exons Defines a More Malignant Phenotype of Breast Cancer With Worsened Survival.

Metodieva G, Adoki S, Lausen B, Metodiev MV.

EBioMedicine. 2016 Jun;8:150-158. doi: 10.1016/j.ebiom.2016.05.009. Epub 2016 May 7.

2.

Mislocalization of the cell polarity protein scribble promotes mammary tumorigenesis and is associated with basal breast cancer.

Feigin ME, Akshinthala SD, Araki K, Rosenberg AZ, Muthuswamy LB, Martin B, Lehmann BD, Berman HK, Pietenpol JA, Cardiff RD, Muthuswamy SK.

Cancer Res. 2014 Jun 1;74(11):3180-94. doi: 10.1158/0008-5472.CAN-13-3415. Epub 2014 Mar 24.

3.

A protein complex of SCRIB, NOS1AP and VANGL1 regulates cell polarity and migration, and is associated with breast cancer progression.

Anastas JN, Biechele TL, Robitaille M, Muster J, Allison KH, Angers S, Moon RT.

Oncogene. 2012 Aug 9;31(32):3696-708. doi: 10.1038/onc.2011.528. Epub 2011 Dec 19.

4.

No association of polymorphisms in the cell polarity gene SCRIB with breast cancer risk in German population.

Zhang C, Zhou P, Li JP.

Breast Cancer Res Treat. 2011 Feb;126(1):257-9. doi: 10.1007/s10549-010-1253-9. Epub 2010 Nov 18. No abstract available.

PMID:
21086040
5.

Mutations in planar cell polarity gene SCRIB are associated with spina bifida.

Lei Y, Zhu H, Duhon C, Yang W, Ross ME, Shaw GM, Finnell RH.

PLoS One. 2013 Jul 26;8(7):e69262. doi: 10.1371/journal.pone.0069262. Print 2013.

6.

Spectrin binding motifs regulate Scribble cortical dynamics and polarity function.

Boëda B, Etienne-Manneville S.

Elife. 2015 Feb 9;4. doi: 10.7554/eLife.04726.

7.

ZDHHC7-mediated S-palmitoylation of Scribble regulates cell polarity.

Chen B, Zheng B, DeRan M, Jarugumilli GK, Fu J, Brooks YS, Wu X.

Nat Chem Biol. 2016 Sep;12(9):686-93. doi: 10.1038/nchembio.2119. Epub 2016 Jul 4.

8.

No association of polymorphisms in the cell polarity gene SCRIB with breast cancer risk.

Dünnebier T, Schlaefer K, Gilbert M, Baisch C, Justenhoven C, Brauch H, Harth V, Spickenheuer A, Rabstein S, Pesch B, Brüning T, Ko YD, Hamann U.

Breast Cancer Res Treat. 2011 May;127(1):259-64. doi: 10.1007/s10549-010-1194-3. Epub 2010 Oct 9.

PMID:
20936341
9.

Scribble associates with two polarity proteins, Lgl2 and Vangl2, via distinct molecular domains.

Kallay LM, McNickle A, Brennwald PJ, Hubbard AL, Braiterman LT.

J Cell Biochem. 2006 Oct 1;99(2):647-64.

PMID:
16791850
10.

Aberrant overexpression of the cell polarity module scribble in human cancer.

Vaira V, Faversani A, Dohi T, Maggioni M, Nosotti M, Tosi D, Altieri DC, Bosari S.

Am J Pathol. 2011 Jun;178(6):2478-83. doi: 10.1016/j.ajpath.2011.02.028. Epub 2011 May 6.

11.

The tumor suppressor Scrib interacts with the zyxin-related protein LPP, which shuttles between cell adhesion sites and the nucleus.

Petit MM, Meulemans SM, Alen P, Ayoubi TA, Jansen E, Van de Ven WJ.

BMC Cell Biol. 2005 Jan 13;6(1):1.

12.

SCRIB expression is deregulated in human prostate cancer, and its deficiency in mice promotes prostate neoplasia.

Pearson HB, Perez-Mancera PA, Dow LE, Ryan A, Tennstedt P, Bogani D, Elsum I, Greenfield A, Tuveson DA, Simon R, Humbert PO.

J Clin Invest. 2011 Nov;121(11):4257-67. doi: 10.1172/JCI58509. Epub 2011 Oct 3.

13.

Exon-based clustering of murine breast tumor transcriptomes reveals alternative exons whose expression is associated with metastasis.

Dutertre M, Lacroix-Triki M, Driouch K, de la Grange P, Gratadou L, Beck S, Millevoi S, Tazi J, Lidereau R, Vagner S, Auboeuf D.

Cancer Res. 2010 Feb 1;70(3):896-905. doi: 10.1158/0008-5472.CAN-09-2703. Epub 2010 Jan 26.

14.

Aberrant alternative exon use and increased copy number of human metalloprotease-disintegrin ADAM15 gene in breast cancer cells.

Ortiz RM, Kärkkäinen I, Huovila AP.

Genes Chromosomes Cancer. 2004 Dec;41(4):366-78.

PMID:
15384173
15.

Splicing factor Tra2-beta1 is specifically induced in breast cancer and regulates alternative splicing of the CD44 gene.

Watermann DO, Tang Y, Zur Hausen A, Jäger M, Stamm S, Stickeler E.

Cancer Res. 2006 May 1;66(9):4774-80.

16.

[Scrib, a tumor suppressor gene involved in cell polarity].

Osmani N, Etienne-Manneville S.

Med Sci (Paris). 2008 Jan;24(1):61-4. doi: 10.1051/medsci/200824161. French.

17.

Exon-level transcriptome profiling in murine breast cancer reveals splicing changes specific to tumors with different metastatic abilities.

Bemmo A, Dias C, Rose AA, Russo C, Siegel P, Majewski J.

PLoS One. 2010 Aug 6;5(8):e11981. doi: 10.1371/journal.pone.0011981.

18.

The polarity protein Scrib is essential for directed endothelial cell migration.

Michaelis UR, Chavakis E, Kruse C, Jungblut B, Kaluza D, Wandzioch K, Manavski Y, Heide H, Santoni MJ, Potente M, Eble JA, Borg JP, Brandes RP.

Circ Res. 2013 Mar 15;112(6):924-34. doi: 10.1161/CIRCRESAHA.112.300592. Epub 2013 Jan 29.

PMID:
23362312
19.

Exon-level microarray analyses identify alternative splicing programs in breast cancer.

Lapuk A, Marr H, Jakkula L, Pedro H, Bhattacharya S, Purdom E, Hu Z, Simpson K, Pachter L, Durinck S, Wang N, Parvin B, Fontenay G, Speed T, Garbe J, Stampfer M, Bayandorian H, Dorton S, Clark TA, Schweitzer A, Wyrobek A, Feiler H, Spellman P, Conboy J, Gray JW.

Mol Cancer Res. 2010 Jul;8(7):961-74. doi: 10.1158/1541-7786.MCR-09-0528. Epub 2010 Jul 6.

20.

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