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Items: 1 to 20 of 164

1.

High-Throughput Small Interfering RNA Screening Identifies Phosphatidylinositol 3-Kinase Class II Alpha as Important for Production of Human Cytomegalovirus Virions.

Polachek WS, Moshrif HF, Franti M, Coen DM, Sreenu VB, Strang BL.

J Virol. 2016 Aug 26;90(18):8360-71. doi: 10.1128/JVI.01134-16. Print 2016 Sep 15.

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Innate nuclear sensor IFI16 translocates into the cytoplasm during the early stage of in vitro human cytomegalovirus infection and is entrapped in the egressing virions during the late stage.

Dell'Oste V, Gatti D, Gugliesi F, De Andrea M, Bawadekar M, Lo Cigno I, Biolatti M, Vallino M, Marschall M, Gariglio M, Landolfo S.

J Virol. 2014 Jun;88(12):6970-82. doi: 10.1128/JVI.00384-14. Epub 2014 Apr 2.

4.

Human cytomegalovirus replication is strictly inhibited by siRNAs targeting UL54, UL97 or UL122/123 gene transcripts.

Hamilton ST, Milbradt J, Marschall M, Rawlinson WD.

PLoS One. 2014 Jun 2;9(6):e97231. doi: 10.1371/journal.pone.0097231. eCollection 2014.

5.

High-throughput screening of a GlaxoSmithKline protein kinase inhibitor set identifies an inhibitor of human cytomegalovirus replication that prevents CREB and histone H3 post-translational modification.

Khan AS, Murray MJ, Ho CMK, Zuercher WJ, Reeves MB, Strang BL.

J Gen Virol. 2017 Apr;98(4):754-768. doi: 10.1099/jgv.0.000713. Epub 2017 Apr 20.

6.

Expression of Oncogenic Alleles Induces Multiple Blocks to Human Cytomegalovirus Infection.

Xu S, Schafer X, Munger J.

J Virol. 2016 Apr 14;90(9):4346-4356. doi: 10.1128/JVI.00179-16. Print 2016 May.

7.

Cyclophilin A is required for efficient human cytomegalovirus DNA replication and reactivation.

Keyes LR, Bego MG, Soland M, St Jeor S.

J Gen Virol. 2012 Apr;93(Pt 4):722-32. doi: 10.1099/vir.0.037309-0. Epub 2012 Jan 13.

8.

RNA interference-mediated targeting of human cytomegalovirus immediate-early or early gene products inhibits viral replication with differential effects on cellular functions.

Xiaofei E, Stadler BM, Debatis M, Wang S, Lu S, Kowalik TF.

J Virol. 2012 May;86(10):5660-73. doi: 10.1128/JVI.06338-11. Epub 2012 Mar 21.

9.

Identification of human cytomegalovirus genes important for biogenesis of the cytoplasmic virion assembly complex.

Das S, Ortiz DA, Gurczynski SJ, Khan F, Pellett PE.

J Virol. 2014 Aug;88(16):9086-99. doi: 10.1128/JVI.01141-14. Epub 2014 Jun 4.

10.

An epistatic relationship between the viral protein kinase UL97 and the UL133-UL138 latency locus during the human cytomegalovirus lytic cycle.

Li G, Rak M, Nguyen CC, Umashankar M, Goodrum FD, Kamil JP.

J Virol. 2014 Jun;88(11):6047-60. doi: 10.1128/JVI.00447-14. Epub 2014 Mar 12.

11.

WDR5 Facilitates Human Cytomegalovirus Replication by Promoting Capsid Nuclear Egress.

Yang B, Liu XJ, Yao Y, Jiang X, Wang XZ, Yang H, Sun JY, Miao Y, Wang W, Huang ZL, Wang Y, Tang Q, Rayner S, Britt WJ, McVoy MA, Luo MH, Zhao F.

J Virol. 2018 Apr 13;92(9). pii: e00207-18. doi: 10.1128/JVI.00207-18. Print 2018 May 1.

12.

Potent Inhibition of Human Cytomegalovirus by Modulation of Cellular SNARE Syntaxin 5.

Cruz L, Streck NT, Ferguson K, Desai T, Desai DH, Amin SG, Buchkovich NJ.

J Virol. 2016 Dec 16;91(1). pii: e01637-16. doi: 10.1128/JVI.01637-16. Print 2017 Jan 1.

13.

Analysis of human cytomegalovirus replication in primary cultured human corneal endothelial cells.

Hosogai M, Shima N, Nakatani Y, Inoue T, Iso T, Yokoo H, Yorifuji H, Akiyama H, Kishi S, Isomura H.

Br J Ophthalmol. 2015 Nov;99(11):1583-90. doi: 10.1136/bjophthalmol-2014-306486. Epub 2015 Aug 10.

14.

Nucleolin associates with the human cytomegalovirus DNA polymerase accessory subunit UL44 and is necessary for efficient viral replication.

Strang BL, Boulant S, Coen DM.

J Virol. 2010 Feb;84(4):1771-84. doi: 10.1128/JVI.01510-09. Epub 2009 Dec 9.

15.

Inhibition of calmodulin-dependent kinase kinase blocks human cytomegalovirus-induced glycolytic activation and severely attenuates production of viral progeny.

McArdle J, Schafer XL, Munger J.

J Virol. 2011 Jan;85(2):705-14. doi: 10.1128/JVI.01557-10. Epub 2010 Nov 17. Erratum in: J Virol. 2013 Jun;87(12):7197.

16.

Dynamic and nucleolin-dependent localization of human cytomegalovirus UL84 to the periphery of viral replication compartments and nucleoli.

Bender BJ, Coen DM, Strang BL.

J Virol. 2014 Oct;88(20):11738-47. doi: 10.1128/JVI.01889-14. Epub 2014 Jul 30.

17.

Tropism of human cytomegalovirus for endothelial cells is determined by a post-entry step dependent on efficient translocation to the nucleus.

Sinzger C, Kahl M, Laib K, Klingel K, Rieger P, Plachter B, Jahn G.

J Gen Virol. 2000 Dec;81(Pt 12):3021-35.

PMID:
11086133
18.
19.

Identification of lead anti-human cytomegalovirus compounds targeting MAP4K4 via machine learning analysis of kinase inhibitor screening data.

Strang BL, Asquith CRM, Moshrif HF, Ho CM, Zuercher WJ, Al-Ali H.

PLoS One. 2018 Jul 26;13(7):e0201321. doi: 10.1371/journal.pone.0201321. eCollection 2018.

20.

Human cytomegalovirus exploits interferon-induced transmembrane proteins to facilitate morphogenesis of the virion assembly compartment.

Xie M, Xuan B, Shan J, Pan D, Sun Y, Shan Z, Zhang J, Yu D, Li B, Qian Z.

J Virol. 2015 Mar;89(6):3049-61. doi: 10.1128/JVI.03416-14. Epub 2014 Dec 31.

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