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Items: 1 to 20 of 73

1.

Fat4-Dchs1 signalling controls cell proliferation in developing vertebrae.

Kuta A, Mao Y, Martin T, Ferreira de Sousa C, Whiting D, Zakaria S, Crespo-Enriquez I, Evans P, Balczerski B, Mankoo B, Irvine KD, Francis-West PH.

Development. 2016 Jul 1;143(13):2367-75. doi: 10.1242/dev.131037.

2.

Characterization of a Dchs1 mutant mouse reveals requirements for Dchs1-Fat4 signaling during mammalian development.

Mao Y, Mulvaney J, Zakaria S, Yu T, Morgan KM, Allen S, Basson MA, Francis-West P, Irvine KD.

Development. 2011 Mar;138(5):947-57. doi: 10.1242/dev.057166.

3.

Dchs1-Fat4 regulation of osteogenic differentiation in mouse.

Crespo-Enriquez I, Hodgson T, Zakaria S, Cadoni E, Shah M, Allen S, Al-Khishali A, Mao Y, Yiu A, Petzold J, Villagomez-Olea G, Pitsillides AA, Irvine KD, Francis-West P.

Development. 2019 Jul 29;146(14). pii: dev176776. doi: 10.1242/dev.176776.

PMID:
31358536
4.

Stromal Fat4 acts non-autonomously with Dchs1/2 to restrict the nephron progenitor pool.

Bagherie-Lachidan M, Reginensi A, Pan Q, Zaveri HP, Scott DA, Blencowe BJ, Helmbacher F, McNeill H.

Development. 2015 Aug 1;142(15):2564-73. doi: 10.1242/dev.122648. Epub 2015 Jun 26.

5.

Regulation of neuronal migration by Dchs1-Fat4 planar cell polarity.

Zakaria S, Mao Y, Kuta A, de Sousa CF, Gaufo GO, McNeill H, Hindges R, Guthrie S, Irvine KD, Francis-West PH.

Curr Biol. 2014 Jul 21;24(14):1620-1627. doi: 10.1016/j.cub.2014.05.067. Epub 2014 Jul 3.

6.

Dchs1-Fat4 regulation of polarized cell behaviours during skeletal morphogenesis.

Mao Y, Kuta A, Crespo-Enriquez I, Whiting D, Martin T, Mulvaney J, Irvine KD, Francis-West P.

Nat Commun. 2016 May 5;7:11469. doi: 10.1038/ncomms11469.

7.

Mutations in genes encoding the cadherin receptor-ligand pair DCHS1 and FAT4 disrupt cerebral cortical development.

Cappello S, Gray MJ, Badouel C, Lange S, Einsiedler M, Srour M, Chitayat D, Hamdan FF, Jenkins ZA, Morgan T, Preitner N, Uster T, Thomas J, Shannon P, Morrison V, Di Donato N, Van Maldergem L, Neuhann T, Newbury-Ecob R, Swinkells M, Terhal P, Wilson LC, Zwijnenburg PJ, Sutherland-Smith AJ, Black MA, Markie D, Michaud JL, Simpson MA, Mansour S, McNeill H, Götz M, Robertson SP.

Nat Genet. 2013 Nov;45(11):1300-8. doi: 10.1038/ng.2765. Epub 2013 Sep 22.

PMID:
24056717
8.

Amotl1 mediates sequestration of the Hippo effector Yap1 downstream of Fat4 to restrict heart growth.

Ragni CV, Diguet N, Le Garrec JF, Novotova M, Resende TP, Pop S, Charon N, Guillemot L, Kitasato L, Badouel C, Dufour A, Olivo-Marin JC, Trouvé A, McNeill H, Meilhac SM.

Nat Commun. 2017 Feb 27;8:14582. doi: 10.1038/ncomms14582.

9.

Fat4/Dchs1 signaling between stromal and cap mesenchyme cells influences nephrogenesis and ureteric bud branching.

Mao Y, Francis-West P, Irvine KD.

Development. 2015 Aug 1;142(15):2574-85. doi: 10.1242/dev.122630. Epub 2015 Jun 26.

10.

Functional interactions between Fat family cadherins in tissue morphogenesis and planar polarity.

Saburi S, Hester I, Goodrich L, McNeill H.

Development. 2012 May;139(10):1806-20. doi: 10.1242/dev.077461.

11.

Fat4 suppression induces Yap translocation accounting for the promoted proliferation and migration of gastric cancer cells.

Ma L, Cui J, Xi H, Bian S, Wei B, Chen L.

Cancer Biol Ther. 2016;17(1):36-47. doi: 10.1080/15384047.2015.1108488.

12.

Loss of Mob1a/b in mice results in chondrodysplasia due to YAP1/TAZ-TEAD-dependent repression of SOX9.

Goto H, Nishio M, To Y, Oishi T, Miyachi Y, Maehama T, Nishina H, Akiyama H, Mak TW, Makii Y, Saito T, Yasoda A, Tsumaki N, Suzuki A.

Development. 2018 Mar 16;145(6). pii: dev159244. doi: 10.1242/dev.159244.

13.

Function and cancer genomics of FAT family genes (review).

Katoh M.

Int J Oncol. 2012 Dec;41(6):1913-8. doi: 10.3892/ijo.2012.1669. Epub 2012 Oct 17. Review.

14.

Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease.

Saburi S, Hester I, Fischer E, Pontoglio M, Eremina V, Gessler M, Quaggin SE, Harrison R, Mount R, McNeill H.

Nat Genet. 2008 Aug;40(8):1010-5. doi: 10.1038/ng.179. Epub 2008 Jul 6.

PMID:
18604206
15.

Pro-invasive activity of the Hippo pathway effectors YAP and TAZ in cutaneous melanoma.

Nallet-Staub F, Marsaud V, Li L, Gilbert C, Dodier S, Bataille V, Sudol M, Herlyn M, Mauviel A.

J Invest Dermatol. 2014 Jan;134(1):123-132. doi: 10.1038/jid.2013.319. Epub 2013 Jul 29.

16.

Inhibitory mechanism of FAT4 gene expression in response to actin dynamics during Src-induced carcinogenesis.

Ito T, Taniguchi H, Fukagai K, Okamuro S, Kobayashi A.

PLoS One. 2015 Feb 13;10(2):e0118336. doi: 10.1371/journal.pone.0118336. eCollection 2015.

17.

A YAP/TAZ-Regulated Molecular Signature Is Associated with Oral Squamous Cell Carcinoma.

Hiemer SE, Zhang L, Kartha VK, Packer TS, Almershed M, Noonan V, Kukuruzinska M, Bais MV, Monti S, Varelas X.

Mol Cancer Res. 2015 Jun;13(6):957-68. doi: 10.1158/1541-7786.MCR-14-0580. Epub 2015 Mar 20.

18.

Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis.

Liu F, Lagares D, Choi KM, Stopfer L, Marinković A, Vrbanac V, Probst CK, Hiemer SE, Sisson TH, Horowitz JC, Rosas IO, Fredenburgh LE, Feghali-Bostwick C, Varelas X, Tager AM, Tschumperlin DJ.

Am J Physiol Lung Cell Mol Physiol. 2015 Feb 15;308(4):L344-57. doi: 10.1152/ajplung.00300.2014. Epub 2014 Dec 12.

19.

Yes-associated protein (YAP) is a negative regulator of chondrogenesis in mesenchymal stem cells.

Karystinou A, Roelofs AJ, Neve A, Cantatore FP, Wackerhage H, De Bari C.

Arthritis Res Ther. 2015 May 30;17:147. doi: 10.1186/s13075-015-0639-9.

20.

Mutations in DCHS1 cause mitral valve prolapse.

Durst R, Sauls K, Peal DS, deVlaming A, Toomer K, Leyne M, Salani M, Talkowski ME, Brand H, Perrocheau M, Simpson C, Jett C, Stone MR, Charles F, Chiang C, Lynch SN, Bouatia-Naji N, Delling FN, Freed LA, Tribouilloy C, Le Tourneau T, LeMarec H, Fernandez-Friera L, Solis J, Trujillano D, Ossowski S, Estivill X, Dina C, Bruneval P, Chester A, Schott JJ, Irvine KD, Mao Y, Wessels A, Motiwala T, Puceat M, Tsukasaki Y, Menick DR, Kasiganesan H, Nie X, Broome AM, Williams K, Johnson A, Markwald RR, Jeunemaitre X, Hagege A, Levine RA, Milan DJ, Norris RA, Slaugenhaupt SA.

Nature. 2015 Sep 3;525(7567):109-13. doi: 10.1038/nature14670. Epub 2015 Aug 10.

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