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Items: 1 to 20 of 70

1.

Immuno-PET Imaging of Engineered Human T Cells in Tumors.

Mall S, Yusufi N, Wagner R, Klar R, Bianchi H, Steiger K, Straub M, Audehm S, Laitinen I, Aichler M, Peschel C, Ziegler S, Mustafa M, Schwaiger M, D'Alessandria C, Krackhardt AM.

Cancer Res. 2016 Jul 15;76(14):4113-23. doi: 10.1158/0008-5472.CAN-15-2784. Epub 2016 Jun 28.

2.

In-depth Characterization of a TCR-specific Tracer for Sensitive Detection of Tumor-directed Transgenic T Cells by Immuno-PET.

Yusufi N, Mall S, Bianchi HO, Steiger K, Reder S, Klar R, Audehm S, Mustafa M, Nekolla S, Peschel C, Schwaiger M, Krackhardt AM, D'Alessandria C.

Theranostics. 2017 Jun 15;7(9):2402-2416. doi: 10.7150/thno.17994. eCollection 2017.

3.

T-cell functionality testing is highly relevant to developing novel immuno-tracers monitoring T cells in the context of immunotherapies and revealed CD7 as an attractive target.

Mayer KE, Mall S, Yusufi N, Gosmann D, Steiger K, Russelli L, Bianchi HO, Audehm S, Wagner R, Bräunlein E, Stelzl A, Bassermann F, Weichert W, Weber W, Schwaiger M, D'Alessandria C, Krackhardt AM.

Theranostics. 2018 Nov 28;8(21):6070-6087. doi: 10.7150/thno.27275. eCollection 2018.

4.

Kinetic phases of distribution and tumor targeting by T cell receptor engineered lymphocytes inducing robust antitumor responses.

Koya RC, Mok S, Comin-Anduix B, Chodon T, Radu CG, Nishimura MI, Witte ON, Ribas A.

Proc Natl Acad Sci U S A. 2010 Aug 10;107(32):14286-91. doi: 10.1073/pnas.1008300107. Epub 2010 Jul 12.

5.

Immuno-PET imaging of tumor endothelial marker 8 (TEM8).

Kuo F, Histed S, Xu B, Bhadrasetty V, Szajek LP, Williams MR, Wong K, Wu H, Lane K, Coble V, Vasalatiy O, Griffiths GL, Paik CH, Elbuluk O, Szot C, Chaudhary A, St Croix B, Choyke P, Jagoda EM.

Mol Pharm. 2014 Nov 3;11(11):3996-4006. doi: 10.1021/mp500056d. Epub 2014 Jul 11.

6.

Human effector T cells derived from central memory cells rather than CD8(+)T cells modified by tumor-specific TCR gene transfer possess superior traits for adoptive immunotherapy.

Wu F, Zhang W, Shao H, Bo H, Shen H, Li J, Liu Y, Wang T, Ma W, Huang S.

Cancer Lett. 2013 Oct 10;339(2):195-207. doi: 10.1016/j.canlet.2013.06.009. Epub 2013 Jun 18.

PMID:
23791878
7.

In vivo programming of tumor antigen-specific T lymphocytes from pluripotent stem cells to promote cancer immunosurveillance.

Lei F, Zhao B, Haque R, Xiong X, Budgeon L, Christensen ND, Wu Y, Song J.

Cancer Res. 2011 Jul 15;71(14):4742-7. doi: 10.1158/0008-5472.CAN-11-0359. Epub 2011 May 31.

8.

Noninvasive detection of tumor-infiltrating T cells by PET reporter imaging.

McCracken MN, Vatakis DN, Dixit D, McLaughlin J, Zack JA, Witte ON.

J Clin Invest. 2015 May;125(5):1815-26. doi: 10.1172/JCI77326. Epub 2015 Mar 30.

9.

Glypican-3-targeting F(ab')2 for 89Zr PET of hepatocellular carcinoma.

Sham JG, Kievit FM, Grierson JR, Chiarelli PA, Miyaoka RS, Zhang M, Yeung RS, Minoshima S, Park JO.

J Nucl Med. 2014 Dec;55(12):2032-7. doi: 10.2967/jnumed.114.145102. Epub 2014 Oct 30.

10.

Chimeric antigen receptor engineering: a right step in the evolution of adoptive cellular immunotherapy.

Figueroa JA, Reidy A, Mirandola L, Trotter K, Suvorava N, Figueroa A, Konala V, Aulakh A, Littlefield L, Grizzi F, Rahman RL, Jenkins MR, Musgrove B, Radhi S, D'Cunha N, D'Cunha LN, Hermonat PL, Cobos E, Chiriva-Internati M.

Int Rev Immunol. 2015 Mar;34(2):154-87. doi: 10.3109/08830185.2015.1018419. Review.

PMID:
25901860
11.

PET of hypoxia with 89Zr-labeled cG250-F(ab')2 in head and neck tumors.

Hoeben BA, Kaanders JH, Franssen GM, Troost EG, Rijken PF, Oosterwijk E, van Dongen GA, Oyen WJ, Boerman OC, Bussink J.

J Nucl Med. 2010 Jul;51(7):1076-83. doi: 10.2967/jnumed.109.073189. Epub 2010 Jun 16.

12.

Quantitative PET reporter gene imaging of CD8+ T cells specific for a melanoma-expressed self-antigen.

Shu CJ, Radu CG, Shelly SM, Vo DD, Prins R, Ribas A, Phelps ME, Witte ON.

Int Immunol. 2009 Feb;21(2):155-65. doi: 10.1093/intimm/dxn133. Epub 2008 Dec 23.

13.

TCR-transgenic lymphocytes specific for HMMR/Rhamm limit tumor outgrowth in vivo.

Spranger S, Jeremias I, Wilde S, Leisegang M, Stärck L, Mosetter B, Uckert W, Heemskerk MH, Schendel DJ, Frankenberger B.

Blood. 2012 Apr 12;119(15):3440-9. doi: 10.1182/blood-2011-06-357939. Epub 2012 Feb 27.

PMID:
22371883
14.

Hematopoietic stem cells for cancer immunotherapy.

Gschweng E, De Oliveira S, Kohn DB.

Immunol Rev. 2014 Jan;257(1):237-49. doi: 10.1111/imr.12128. Review.

15.

T Cells Engineered With Chimeric Antigen Receptors Targeting NKG2D Ligands Display Lethal Toxicity in Mice.

VanSeggelen H, Hammill JA, Dvorkin-Gheva A, Tantalo DG, Kwiecien JM, Denisova GF, Rabinovich B, Wan Y, Bramson JL.

Mol Ther. 2015 Oct;23(10):1600-10. doi: 10.1038/mt.2015.119. Epub 2015 Jun 30.

16.

An Effective Immuno-PET Imaging Method to Monitor CD8-Dependent Responses to Immunotherapy.

Tavaré R, Escuin-Ordinas H, Mok S, McCracken MN, Zettlitz KA, Salazar FB, Witte ON, Ribas A, Wu AM.

Cancer Res. 2016 Jan 1;76(1):73-82. doi: 10.1158/0008-5472.CAN-15-1707. Epub 2015 Nov 16.

17.

Application of adoptive T-cell therapy using tumor antigen-specific T-cell receptor gene transfer for the treatment of human leukemia.

Ochi T, Fujiwara H, Yasukawa M.

J Biomed Biotechnol. 2010;2010:521248. doi: 10.1155/2010/521248. Epub 2010 May 5. Review.

18.

Genetically modulating T-cell function to target cancer.

Merhavi-Shoham E, Haga-Friedman A, Cohen CJ.

Semin Cancer Biol. 2012 Feb;22(1):14-22. doi: 10.1016/j.semcancer.2011.12.006. Epub 2011 Dec 24. Review.

PMID:
22210183
19.

Co-introduced functional CCR2 potentiates in vivo anti-lung cancer functionality mediated by T cells double gene-modified to express WT1-specific T-cell receptor.

Asai H, Fujiwara H, An J, Ochi T, Miyazaki Y, Nagai K, Okamoto S, Mineno J, Kuzushima K, Shiku H, Inoue H, Yasukawa M.

PLoS One. 2013;8(2):e56820. doi: 10.1371/journal.pone.0056820. Epub 2013 Feb 18.

20.

Trafficking of CAR-engineered human T cells following regional or systemic adoptive transfer in SCID beige mice.

Parente-Pereira AC, Burnet J, Ellison D, Foster J, Davies DM, van der Stegen S, Burbridge S, Chiapero-Stanke L, Wilkie S, Mather S, Maher J.

J Clin Immunol. 2011 Aug;31(4):710-8. doi: 10.1007/s10875-011-9532-8. Epub 2011 Apr 20.

PMID:
21505816

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