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Items: 1 to 20 of 96

1.

NMR Characterization of Information Flow and Allosteric Communities in the MAP Kinase p38γ.

Aoto PC, Martin BT, Wright PE.

Sci Rep. 2016 Jun 29;6:28655. doi: 10.1038/srep28655.

2.

p38γ activation triggers dynamical changes in allosteric docking sites.

Rodriguez Limardo RG, Ferreiro DN, Roitberg AE, Marti MA, Turjanski AG.

Biochemistry. 2011 Mar 1;50(8):1384-95. doi: 10.1021/bi1007518. Epub 2011 Feb 7.

PMID:
21235211
3.

Reciprocal allosteric regulation of p38γ and PTPN3 involves a PDZ domain-modulated complex formation.

Chen KE, Lin SY, Wu MJ, Ho MR, Santhanam A, Chou CC, Meng TC, Wang AH.

Sci Signal. 2014 Oct 14;7(347):ra98. doi: 10.1126/scisignal.2005722.

PMID:
25314968
4.
5.

Molecular Basis of the Interaction of the Human Protein Tyrosine Phosphatase Non-receptor Type 4 (PTPN4) with the Mitogen-activated Protein Kinase p38γ.

Maisonneuve P, Caillet-Saguy C, Vaney MC, Bibi-Zainab E, Sawyer K, Raynal B, Haouz A, Delepierre M, Lafon M, Cordier F, Wolff N.

J Biol Chem. 2016 Aug 5;291(32):16699-708. doi: 10.1074/jbc.M115.707208. Epub 2016 May 31.

6.

PTPH1 dephosphorylates and cooperates with p38gamma MAPK to increase ras oncogenesis through PDZ-mediated interaction.

Hou SW, Zhi HY, Pohl N, Loesch M, Qi XM, Li RS, Basir Z, Chen G.

Cancer Res. 2010 Apr 1;70(7):2901-10. doi: 10.1158/0008-5472.CAN-09-3229. Epub 2010 Mar 23.

7.

p38γ Mitogen-activated protein kinase signals through phosphorylating its phosphatase PTPH1 in regulating ras protein oncogenesis and stress response.

Hou S, Suresh PS, Qi X, Lepp A, Mirza SP, Chen G.

J Biol Chem. 2012 Aug 10;287(33):27895-905. doi: 10.1074/jbc.M111.335794. Epub 2012 Jun 22.

8.

Essential role for p38alpha MAPK but not p38gamma MAPK in Igf2 expression and myoblast differentiation.

Lovett FA, Cosgrove RA, Gonzalez I, Pell JM.

Endocrinology. 2010 Sep;151(9):4368-80. doi: 10.1210/en.2010-0209. Epub 2010 Jul 7.

PMID:
20610565
9.

The structure of phosphorylated p38gamma is monomeric and reveals a conserved activation-loop conformation.

Bellon S, Fitzgibbon MJ, Fox T, Hsiao HM, Wilson KP.

Structure. 1999 Sep 15;7(9):1057-65.

10.

The stress kinase MRK contributes to regulation of DNA damage checkpoints through a p38gamma-independent pathway.

Tosti E, Waldbaum L, Warshaw G, Gross EA, Ruggieri R.

J Biol Chem. 2004 Nov 12;279(46):47652-60. Epub 2004 Sep 1.

11.
12.

Pro-oncogenic role of alternative p38 mitogen-activated protein kinases p38γ and p38δ, linking inflammation and cancer in colitis-associated colon cancer.

Del Reino P, Alsina-Beauchamp D, Escós A, Cerezo-Guisado MI, Risco A, Aparicio N, Zur R, Fernandez-Estévez M, Collantes E, Montans J, Cuenda A.

Cancer Res. 2014 Nov 1;74(21):6150-60. doi: 10.1158/0008-5472.CAN-14-0870. Epub 2014 Sep 12.

13.

Phosphorylation and stabilization of topoisomerase IIα protein by p38γ mitogen-activated protein kinase sensitize breast cancer cells to its poisons.

Qi X, Hou S, Lepp A, Li R, Basir Z, Lou Z, Chen G.

J Biol Chem. 2011 Oct 14;286(41):35883-90. doi: 10.1074/jbc.M111.229260. Epub 2011 Aug 30.

14.

p38γ MAPK is required for inflammation-associated colon tumorigenesis.

Yin N, Qi X, Tsai S, Lu Y, Basir Z, Oshima K, Thomas JP, Myers CR, Stoner G, Chen G.

Oncogene. 2016 Feb 25;35(8):1039-48. doi: 10.1038/onc.2015.158. Epub 2015 May 11.

PMID:
25961922
15.

p38γ mitogen-activated protein kinase (MAPK) confers breast cancer hormone sensitivity by switching estrogen receptor (ER) signaling from classical to nonclassical pathway via stimulating ER phosphorylation and c-Jun transcription.

Qi X, Zhi H, Lepp A, Wang P, Huang J, Basir Z, Chitambar CR, Myers CR, Chen G.

J Biol Chem. 2012 Apr 27;287(18):14681-91. doi: 10.1074/jbc.M112.349357. Epub 2012 Mar 7.

16.

Loss of p38gamma MAPK induces pleiotropic mitotic defects and massive cell death.

Kukkonen-Macchi A, Sicora O, Kaczynska K, Oetken-Lindholm C, Pouwels J, Laine L, Kallio MJ.

J Cell Sci. 2011 Jan 15;124(Pt 2):216-27. doi: 10.1242/jcs.068254. Epub 2010 Dec 15.

18.

p38γ regulates UV-induced checkpoint signaling and repair of UV-induced DNA damage.

Wu CC, Wu X, Han J, Sun P.

Protein Cell. 2010 Jun;1(6):573-83. doi: 10.1007/s13238-010-0075-1.

19.

ErbB4 Activated p38γ MAPK Isoform Mediates Early Cardiogenesis Through NKx2.5 in Human Pluripotent Stem Cells.

Ramachandra CJ, Mehta A, Wong P, Shim W.

Stem Cells. 2016 Feb;34(2):288-98. doi: 10.1002/stem.2223. Epub 2015 Oct 15.

20.

Alternative p38 MAPKs are essential for collagen-induced arthritis.

Criado G, Risco A, Alsina-Beauchamp D, Pérez-Lorenzo MJ, Escós A, Cuenda A.

Arthritis Rheumatol. 2014 May;66(5):1208-17. doi: 10.1002/art.38327.

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