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Concurrent validity of different functional and neuroproteomic pain assessment methods in the rat osteoarthritis monosodium iodoacetate (MIA) model.

Otis C, Gervais J, Guillot M, Gervais JA, Gauvin D, P├ęthel C, Authier S, Dansereau MA, Sarret P, Martel-Pelletier J, Pelletier JP, Beaudry F, Troncy E.

Arthritis Res Ther. 2016 Jun 23;18:150. doi: 10.1186/s13075-016-1047-5.


Spinal neuropeptide modulation, functional assessment and cartilage lesions in a monosodium iodoacetate rat model of osteoarthritis.

Otis C, Guillot M, Moreau M, Martel-Pelletier J, Pelletier JP, Beaudry F, Troncy E.

Neuropeptides. 2017 Oct;65:56-62. doi: 10.1016/j.npep.2017.04.009. Epub 2017 Apr 24.


Dissecting the contribution of knee joint NGF to spinal nociceptive sensitization in a model of OA pain in the rat.

Sagar DR, Nwosu L, Walsh DA, Chapman V.

Osteoarthritis Cartilage. 2015 Jun;23(6):906-13. doi: 10.1016/j.joca.2015.01.010. Epub 2015 Jan 24.


Effects of Treadmill Exercise on Advanced Osteoarthritis Pain in Rats.

Allen J, Imbert I, Havelin J, Henderson T, Stevenson G, Liaw L, King T.

Arthritis Rheumatol. 2017 Jul;69(7):1407-1417. doi: 10.1002/art.40101. Epub 2017 Jun 5.


Augmented pain behavioural responses to intra-articular injection of nerve growth factor in two animal models of osteoarthritis.

Ashraf S, Mapp PI, Burston J, Bennett AJ, Chapman V, Walsh DA.

Ann Rheum Dis. 2014 Sep;73(9):1710-8. doi: 10.1136/annrheumdis-2013-203416. Epub 2013 Jul 13.


Sensitivity of functional targeted neuropeptide evaluation in testing pregabalin analgesic efficacy in a rat model of osteoarthritis pain.

Otis C, Guillot M, Moreau M, Pelletier JP, Beaudry F, Troncy E.

Clin Exp Pharmacol Physiol. 2019 Aug;46(8):723-733. doi: 10.1111/1440-1681.13100. Epub 2019 May 23.


Spinal nociceptive reflexes are sensitized in the monosodium iodoacetate model of osteoarthritis pain in the rat.

Kelly S, Dobson KL, Harris J.

Osteoarthritis Cartilage. 2013 Sep;21(9):1327-35. doi: 10.1016/j.joca.2013.07.002.


Blocking the tropomyosin receptor kinase A (TrkA) receptor inhibits pain behaviour in two rat models of osteoarthritis.

Nwosu LN, Mapp PI, Chapman V, Walsh DA.

Ann Rheum Dis. 2016 Jun;75(6):1246-54. doi: 10.1136/annrheumdis-2014-207203. Epub 2015 Aug 18.


The contribution of spinal glial cells to chronic pain behaviour in the monosodium iodoacetate model of osteoarthritic pain.

Sagar DR, Burston JJ, Hathway GJ, Woodhams SG, Pearson RG, Bennett AJ, Kendall DA, Scammell BE, Chapman V.

Mol Pain. 2011 Nov 17;7:88. doi: 10.1186/1744-8069-7-88.


Changes in proinflammatory cytokines, neuropeptides, and microglia in an animal model of monosodium iodoacetate-induced hip osteoarthritis.

Kawarai Y, Orita S, Nakamura J, Miyamoto S, Suzuki M, Inage K, Hagiwara S, Suzuki T, Nakajima T, Akazawa T, Ohtori S.

J Orthop Res. 2018 Nov;36(11):2978-2986. doi: 10.1002/jor.24065. Epub 2018 Jul 13.


Pain-like behaviour and spinal changes in the monosodium iodoacetate model of osteoarthritis in C57Bl/6 mice.

Ogbonna AC, Clark AK, Gentry C, Hobbs C, Malcangio M.

Eur J Pain. 2013 Apr;17(4):514-26. doi: 10.1002/j.1532-2149.2012.00223.x. Epub 2012 Nov 21.


Differences in structural and pain phenotypes in the sodium monoiodoacetate and meniscal transection models of osteoarthritis.

Mapp PI, Sagar DR, Ashraf S, Burston JJ, Suri S, Chapman V, Walsh DA.

Osteoarthritis Cartilage. 2013 Sep;21(9):1336-45. doi: 10.1016/j.joca.2013.06.031.


Robust anti-nociceptive effects of monoacylglycerol lipase inhibition in a model of osteoarthritis pain.

Burston JJ, Mapp PI, Sarmad S, Barrett DA, Niphakis MJ, Cravatt BF, Walsh DA, Chapman V.

Br J Pharmacol. 2016 Nov;173(21):3134-3144. doi: 10.1111/bph.13574. Epub 2016 Sep 23.


Pain-related behavior and the characteristics of dorsal-root ganglia in a rat model of hip osteoarthritis induced by mono-iodoacetate.

Miyamoto S, Nakamura J, Ohtori S, Orita S, Nakajima T, Omae T, Hagiwara S, Takazawa M, Suzuki M, Suzuki T, Takahashi K.

J Orthop Res. 2017 Jul;35(7):1424-1430. doi: 10.1002/jor.23395. Epub 2017 Apr 17.


The monosodium iodoacetate model of osteoarthritis: a model of chronic nociceptive pain in rats?

Combe R, Bramwell S, Field MJ.

Neurosci Lett. 2004 Nov 11;370(2-3):236-40.


Effect of atorvastatin, a HMG-CoA reductase inhibitor in monosodium iodoacetate-induced osteoarthritic pain: implication for osteoarthritis therapy.

Pathak NN, Balaganur V, Lingaraju MC, Kant V, Kumar D, Kumar D, Sharma AK, Tandan SK.

Pharmacol Rep. 2015 Jun;67(3):513-9. doi: 10.1016/j.pharep.2014.12.005. Epub 2014 Dec 19.


Osteoarthritic pain model influences functional outcomes and spinal neuropeptidomics: A pilot study in female rats.

Gervais JA, Otis C, Lussier B, Guillot M, Martel-Pelletier J, Pelletier JP, Beaudry F, Troncy E.

Can J Vet Res. 2019 Apr;83(2):133-141.


Acute effect of Capparis spinosa root extracts on rat articular pain.

Maresca M, Micheli L, Di Cesare Mannelli L, Tenci B, Innocenti M, Khatib M, Mulinacci N, Ghelardini C.

J Ethnopharmacol. 2016 Dec 4;193:456-465. doi: 10.1016/j.jep.2016.09.032. Epub 2016 Sep 17.


Electrophysiological evidence for voltage-gated calcium channel 2 (Cav2) modulation of mechano- and thermosensitive spinal neuronal responses in a rat model of osteoarthritis.

Rahman W, Patel R, Dickenson AH.

Neuroscience. 2015 Oct 1;305:76-85. doi: 10.1016/j.neuroscience.2015.07.073. Epub 2015 Aug 4.


Adelmidrol, in combination with hyaluronic acid, displays increased anti-inflammatory and analgesic effects against monosodium iodoacetate-induced osteoarthritis in rats.

Di Paola R, Fusco R, Impellizzeri D, Cordaro M, Britti D, Morittu VM, Evangelista M, Cuzzocrea S.

Arthritis Res Ther. 2016 Dec 12;18(1):291.

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