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Items: 1 to 20 of 91

1.

Defining the consequences of genetic variation on a proteome-wide scale.

Chick JM, Munger SC, Simecek P, Huttlin EL, Choi K, Gatti DM, Raghupathy N, Svenson KL, Churchill GA, Gygi SP.

Nature. 2016 Jun 23;534(7608):500-5. doi: 10.1038/nature18270. Epub 2016 Jun 15.

2.

Variation and genetic control of protein abundance in humans.

Wu L, Candille SI, Choi Y, Xie D, Jiang L, Li-Pook-Than J, Tang H, Snyder M.

Nature. 2013 Jul 4;499(7456):79-82. doi: 10.1038/nature12223. Epub 2013 May 15.

3.

Quantitative trait loci mapping of the mouse plasma proteome (pQTL).

Holdt LM, von Delft A, Nicolaou A, Baumann S, Kostrzewa M, Thiery J, Teupser D.

Genetics. 2013 Feb;193(2):601-8. doi: 10.1534/genetics.112.143354. Epub 2012 Nov 19.

4.

Identification and validation of genetic variants that influence transcription factor and cell signaling protein levels.

Hause RJ, Stark AL, Antao NN, Gorsic LK, Chung SH, Brown CD, Wong SS, Gill DF, Myers JL, To LA, White KP, Dolan ME, Jones RB.

Am J Hum Genet. 2014 Aug 7;95(2):194-208. doi: 10.1016/j.ajhg.2014.07.005. Epub 2014 Jul 31.

5.

Impact of genetic variation on synaptic protein levels in genetically diverse mice.

Loos M, Li KW, van der Schors R, Gouwenberg Y, van der Loo R, Williams RW, Smit AB, Spijker S.

Proteomics. 2016 Apr;16(7):1123-30. doi: 10.1002/pmic.201500154. Epub 2016 Mar 10.

PMID:
26786964
6.

Protein quantitative trait loci identify novel candidates modulating cellular response to chemotherapy.

Stark AL, Hause RJ Jr, Gorsic LK, Antao NN, Wong SS, Chung SH, Gill DF, Im HK, Myers JL, White KP, Jones RB, Dolan ME.

PLoS Genet. 2014 Apr 3;10(4):e1004192. doi: 10.1371/journal.pgen.1004192. eCollection 2014 Apr.

7.

Comparative analysis of proteome and transcriptome variation in mouse.

Ghazalpour A, Bennett B, Petyuk VA, Orozco L, Hagopian R, Mungrue IN, Farber CR, Sinsheimer J, Kang HM, Furlotte N, Park CC, Wen PZ, Brewer H, Weitz K, Camp DG 2nd, Pan C, Yordanova R, Neuhaus I, Tilford C, Siemers N, Gargalovic P, Eskin E, Kirchgessner T, Smith DJ, Smith RD, Lusis AJ.

PLoS Genet. 2011 Jun;7(6):e1001393. doi: 10.1371/journal.pgen.1001393. Epub 2011 Jun 9.

8.

Identification of quantitative trait loci underlying proteome variation in human lymphoblastoid cells.

Garge N, Pan H, Rowland MD, Cargile BJ, Zhang X, Cooley PC, Page GP, Bunger MK.

Mol Cell Proteomics. 2010 Jul;9(7):1383-99. doi: 10.1074/mcp.M900378-MCP200. Epub 2010 Feb 23.

9.

Transcriptome and proteome quantification of a tumor model provides novel insights into post-transcriptional gene regulation.

Jüschke C, Dohnal I, Pichler P, Harzer H, Swart R, Ammerer G, Mechtler K, Knoblich JA.

Genome Biol. 2013 Nov 30;14(11):r133. doi: 10.1186/gb-2013-14-11-r133.

10.

Signatures of Evolutionary Adaptation in Quantitative Trait Loci Influencing Trace Element Homeostasis in Liver.

Engelken J, Espadas G, Mancuso FM, Bonet N, Scherr AL, Jímenez-Álvarez V, Codina-Solà M, Medina-Stacey D, Spataro N, Stoneking M, Calafell F, Sabidó E, Bosch E.

Mol Biol Evol. 2016 Mar;33(3):738-54. doi: 10.1093/molbev/msv267. Epub 2015 Nov 17.

11.

Inferring genetic architecture of complex traits using Bayesian integrative analysis of genome and transcriptome data.

Ehsani A, Sørensen P, Pomp D, Allan M, Janss L.

BMC Genomics. 2012 Sep 5;13:456. doi: 10.1186/1471-2164-13-456.

12.

Proteomic studies related to genetic determinants of variability in protein concentrations.

Horvatovich P, Franke L, Bischoff R.

J Proteome Res. 2014 Jan 3;13(1):5-14. doi: 10.1021/pr400765y. Epub 2013 Dec 4. Review.

PMID:
24237071
13.

Genome-wide quantitative trait loci mapping of the human cerebrospinal fluid proteome.

Sasayama D, Hattori K, Ogawa S, Yokota Y, Matsumura R, Teraishi T, Hori H, Ota M, Yoshida S, Kunugi H.

Hum Mol Genet. 2017 Jan 1;26(1):44-51. doi: 10.1093/hmg/ddw366.

PMID:
28031287
14.

Transcriptome and genome sequencing uncovers functional variation in humans.

Lappalainen T, Sammeth M, Friedländer MR, 't Hoen PA, Monlong J, Rivas MA, Gonzàlez-Porta M, Kurbatova N, Griebel T, Ferreira PG, Barann M, Wieland T, Greger L, van Iterson M, Almlöf J, Ribeca P, Pulyakhina I, Esser D, Giger T, Tikhonov A, Sultan M, Bertier G, MacArthur DG, Lek M, Lizano E, Buermans HP, Padioleau I, Schwarzmayr T, Karlberg O, Ongen H, Kilpinen H, Beltran S, Gut M, Kahlem K, Amstislavskiy V, Stegle O, Pirinen M, Montgomery SB, Donnelly P, McCarthy MI, Flicek P, Strom TM; Geuvadis Consortium, Lehrach H, Schreiber S, Sudbrak R, Carracedo A, Antonarakis SE, Häsler R, Syvänen AC, van Ommen GJ, Brazma A, Meitinger T, Rosenstiel P, Guigó R, Gut IG, Estivill X, Dermitzakis ET.

Nature. 2013 Sep 26;501(7468):506-11. doi: 10.1038/nature12531. Epub 2013 Sep 15.

15.

Genetic basis of proteome variation in yeast.

Foss EJ, Radulovic D, Shaffer SA, Ruderfer DM, Bedalov A, Goodlett DR, Kruglyak L.

Nat Genet. 2007 Nov;39(11):1369-75. Epub 2007 Oct 21.

PMID:
17952072
16.

Comparative analysis of different label-free mass spectrometry based protein abundance estimates and their correlation with RNA-Seq gene expression data.

Ning K, Fermin D, Nesvizhskii AI.

J Proteome Res. 2012 Apr 6;11(4):2261-71. doi: 10.1021/pr201052x. Epub 2012 Feb 29.

17.

A complete mass-spectrometric map of the yeast proteome applied to quantitative trait analysis.

Picotti P, Clément-Ziza M, Lam H, Campbell DS, Schmidt A, Deutsch EW, Röst H, Sun Z, Rinner O, Reiter L, Shen Q, Michaelson JJ, Frei A, Alberti S, Kusebauch U, Wollscheid B, Moritz RL, Beyer A, Aebersold R.

Nature. 2013 Feb 14;494(7436):266-70. doi: 10.1038/nature11835. Epub 2013 Jan 20.

18.

Systems proteomics of liver mitochondria function.

Williams EG, Wu Y, Jha P, Dubuis S, Blattmann P, Argmann CA, Houten SM, Amariuta T, Wolski W, Zamboni N, Aebersold R, Auwerx J.

Science. 2016 Jun 10;352(6291):aad0189. doi: 10.1126/science.aad0189.

19.

Quantitative and qualitative proteome characteristics extracted from in-depth integrated genomics and proteomics analysis.

Low TY, van Heesch S, van den Toorn H, Giansanti P, Cristobal A, Toonen P, Schafer S, Hübner N, van Breukelen B, Mohammed S, Cuppen E, Heck AJ, Guryev V.

Cell Rep. 2013 Dec 12;5(5):1469-78. doi: 10.1016/j.celrep.2013.10.041. Epub 2013 Nov 27.

20.

Impact of Alternative Splicing on the Human Proteome.

Liu Y, Gonzàlez-Porta M, Santos S, Brazma A, Marioni JC, Aebersold R, Venkitaraman AR, Wickramasinghe VO.

Cell Rep. 2017 Aug 1;20(5):1229-1241. doi: 10.1016/j.celrep.2017.07.025.

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