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Items: 1 to 20 of 103

1.

BCG lowers plasma cholesterol levels and delays atherosclerotic lesion progression in mice.

van Dam AD, Bekkering S, Crasborn M, van Beek L, van den Berg SM, Vrieling F, Joosten SA, van Harmelen V, de Winther MPJ, Lütjohann D, Lutgens E, Boon MR, Riksen NP, Rensen PCN, Berbée JFP.

Atherosclerosis. 2016 Aug;251:6-14. doi: 10.1016/j.atherosclerosis.2016.05.031. Epub 2016 May 19.

2.

Cholesteryl ester transfer protein decreases high-density lipoprotein and severely aggravates atherosclerosis in APOE*3-Leiden mice.

Westerterp M, van der Hoogt CC, de Haan W, Offerman EH, Dallinga-Thie GM, Jukema JW, Havekes LM, Rensen PC.

Arterioscler Thromb Vasc Biol. 2006 Nov;26(11):2552-9. Epub 2006 Aug 31.

PMID:
16946130
3.

Deuterium-reinforced polyunsaturated fatty acids protect against atherosclerosis by lowering lipid peroxidation and hypercholesterolemia.

Berbée JFP, Mol IM, Milne GL, Pollock E, Hoeke G, Lütjohann D, Monaco C, Rensen PCN, van der Ploeg LHT, Shchepinov MS.

Atherosclerosis. 2017 Sep;264:100-107. doi: 10.1016/j.atherosclerosis.2017.06.916. Epub 2017 Jun 21.

PMID:
28655430
4.

Niacin Reduces Atherosclerosis Development in APOE*3Leiden.CETP Mice Mainly by Reducing NonHDL-Cholesterol.

Kühnast S, Louwe MC, Heemskerk MM, Pieterman EJ, van Klinken JB, van den Berg SA, Smit JW, Havekes LM, Rensen PC, van der Hoorn JW, Princen HM, Jukema JW.

PLoS One. 2013 Jun 19;8(6):e66467. doi: 10.1371/journal.pone.0066467. Print 2013.

5.

Both transient and continuous corticosterone excess inhibit atherosclerotic plaque formation in APOE*3-leiden.CETP mice.

Auvinen HE, Wang Y, Princen H, Romijn JA, Havekes LM, Smit JW, Meijer OC, Biermasz NR, Rensen PC, Pereira AM.

PLoS One. 2013 May 22;8(5):e63882. doi: 10.1371/journal.pone.0063882. Print 2013.

6.

The dual PPARalpha/gamma agonist tesaglitazar blocks progression of pre-existing atherosclerosis in APOE*3Leiden.CETP transgenic mice.

van der Hoorn JW, Jukema JW, Havekes LM, Lundholm E, Camejo G, Rensen PC, Princen HM.

Br J Pharmacol. 2009 Apr;156(7):1067-75. doi: 10.1111/j.1476-5381.2008.00109.x. Epub 2009 Feb 13.

7.

The AT04A vaccine against proprotein convertase subtilisin/kexin type 9 reduces total cholesterol, vascular inflammation, and atherosclerosis in APOE*3Leiden.CETP mice.

Landlinger C, Pouwer MG, Juno C, van der Hoorn JWA, Pieterman EJ, Jukema JW, Staffler G, Princen HMG, Galabova G.

Eur Heart J. 2017 Aug 21;38(32):2499-2507. doi: 10.1093/eurheartj/ehx260.

8.

Exendin-4 decreases liver inflammation and atherosclerosis development simultaneously by reducing macrophage infiltration.

Wang Y, Parlevliet ET, Geerling JJ, van der Tuin SJ, Zhang H, Bieghs V, Jawad AH, Shiri-Sverdlov R, Bot I, de Jager SC, Havekes LM, Romijn JA, Willems van Dijk K, Rensen PC.

Br J Pharmacol. 2014 Feb;171(3):723-34. doi: 10.1111/bph.12490.

9.

Macrophage-specific apoE gene repair reduces diet-induced hyperlipidemia and atherosclerosis in hypomorphic Apoe mice.

Gaudreault N, Kumar N, Olivas VR, Eberlé D, Rapp JH, Raffai RL.

PLoS One. 2012;7(5):e35816. doi: 10.1371/journal.pone.0035816. Epub 2012 May 14.

10.

Acyl-CoA:cholesterol acyltransferase inhibitor avasimibe reduces atherosclerosis in addition to its cholesterol-lowering effect in ApoE*3-Leiden mice.

Delsing DJ, Offerman EH, van Duyvenvoorde W, van Der Boom H, de Wit EC, Gijbels MJ, van Der Laarse A, Jukema JW, Havekes LM, Princen HM.

Circulation. 2001 Apr 3;103(13):1778-86.

PMID:
11282910
11.

Ritonavir protects against the development of atherosclerosis in APOE*3-Leiden mice.

den Boer MA, Westerterp M, de Vries-van der Weij J, Wang Y, Hu L, Espirito Santo SM, Kooistra T, Reiss P, Romijn JA, Havekes LM, Rensen PC.

Atherosclerosis. 2010 Jun;210(2):381-7. doi: 10.1016/j.atherosclerosis.2009.11.043. Epub 2009 Dec 1.

PMID:
20060117
12.

Expression of type IIA secretory phospholipase A2 inhibits cholesteryl ester transfer protein activity in transgenic mice.

Hurt-Camejo E, Gautier T, Rosengren B, Dikkers A, Behrendt M, Grass DS, Rader DJ, Tietge UJ.

Arterioscler Thromb Vasc Biol. 2013 Dec;33(12):2707-14. doi: 10.1161/ATVBAHA.113.301410. Epub 2013 Oct 10.

PMID:
24115030
13.

Resveratrol protects against atherosclerosis, but does not add to the antiatherogenic effect of atorvastatin, in APOE*3-Leiden.CETP mice.

Berbée JF, Wong MC, Wang Y, van der Hoorn JW, Khedoe PP, van Klinken JB, Mol IM, Hiemstra PS, Tsikas D, Romijn JA, Havekes LM, Princen HM, Rensen PC.

J Nutr Biochem. 2013 Aug;24(8):1423-30. doi: 10.1016/j.jnutbio.2012.11.009. Epub 2013 Jan 18.

PMID:
23337345
14.

Human CETP aggravates atherosclerosis by increasing VLDL-cholesterol rather than by decreasing HDL-cholesterol in APOE*3-Leiden mice.

de Vries-van der Weij J, Zadelaar S, Toet K, Havekes LM, Kooistra T, Rensen PC.

Atherosclerosis. 2009 Sep;206(1):153-8. doi: 10.1016/j.atherosclerosis.2009.02.038. Epub 2009 Mar 19.

PMID:
19345354
15.

Effect of low dose atorvastatin versus diet-induced cholesterol lowering on atherosclerotic lesion progression and inflammation in apolipoprotein E*3-Leiden transgenic mice.

Verschuren L, Kleemann R, Offerman EH, Szalai AJ, Emeis SJ, Princen HM, Kooistra T.

Arterioscler Thromb Vasc Biol. 2005 Jan;25(1):161-7. Epub 2004 Oct 28.

PMID:
15514207
16.

Low dose of the liver X receptor agonist, AZ876, reduces atherosclerosis in APOE*3Leiden mice without affecting liver or plasma triglyceride levels.

van der Hoorn J, Lindén D, Lindahl U, Bekkers M, Voskuilen M, Nilsson R, Oscarsson J, Lindstedt E, Princen H.

Br J Pharmacol. 2011 Apr;162(7):1553-63. doi: 10.1111/j.1476-5381.2010.01168.x.

17.

11β-hydroxysteroid dehydrogenase type 1 gene knockout attenuates atherosclerosis and in vivo foam cell formation in hyperlipidemic apoE⁻/⁻ mice.

García RA, Search DJ, Lupisella JA, Ostrowski J, Guan B, Chen J, Yang WP, Truong A, He A, Zhang R, Yan M, Hellings SE, Gargalovic PS, Ryan CS, Watson LM, Langish RA, Shipkova PA, Carson NL, Taylor JR, Yang R, Psaltis GC, Harrity TW, Robl JA, Gordon DA.

PLoS One. 2013;8(2):e53192. doi: 10.1371/journal.pone.0053192. Epub 2013 Feb 1.

18.

Transgenic expression of dominant-active IDOL in liver causes diet-induced hypercholesterolemia and atherosclerosis in mice.

Calkin AC, Lee SD, Kim J, Van Stijn CM, Wu XH, Lusis AJ, Hong C, Tangirala RI, Tontonoz P.

Circ Res. 2014 Aug 1;115(4):442-9. doi: 10.1161/CIRCRESAHA.115.304440. Epub 2014 Jun 16.

19.

Overexpression of angiopoietin-like protein 4 protects against atherosclerosis development.

Georgiadi A, Wang Y, Stienstra R, Tjeerdema N, Janssen A, Stalenhoef A, van der Vliet JA, de Roos A, Tamsma JT, Smit JW, Tan NS, Müller M, Rensen PC, Kersten S.

Arterioscler Thromb Vasc Biol. 2013 Jul;33(7):1529-37. doi: 10.1161/ATVBAHA.113.301698. Epub 2013 May 2.

PMID:
23640487
20.

CETP expression reverses the reconstituted HDL-induced increase in VLDL.

Wang Y, Berbée JF, Stroes ES, Smit JW, Havekes LM, Romijn JA, Rensen PC.

J Lipid Res. 2011 Aug;52(8):1533-41. doi: 10.1194/jlr.M016659. Epub 2011 May 23.

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