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Items: 1 to 20 of 99

1.

The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas.

Fang D, Gan H, Lee JH, Han J, Wang Z, Riester SM, Jin L, Chen J, Zhou H, Wang J, Zhang H, Yang N, Bradley EW, Ho TH, Rubin BP, Bridge JA, Thibodeau SN, Ordog T, Chen Y, van Wijnen AJ, Oliveira AM, Xu RM, Westendorf JJ, Zhang Z.

Science. 2016 Jun 10;352(6291):1344-8. doi: 10.1126/science.aae0065. Epub 2016 May 26.

2.

Probe the function of histone lysine 36 methylation using histone H3 lysine 36 to methionine mutant transgene in mammalian cells.

Fang D, Gan H, Wang H, Zhou H, Zhang Z.

Cell Cycle. 2017 Oct 2;16(19):1781-1789. doi: 10.1080/15384101.2017.1281483. Epub 2017 Jan 27.

3.

Histone H3K36 mutations promote sarcomagenesis through altered histone methylation landscape.

Lu C, Jain SU, Hoelper D, Bechet D, Molden RC, Ran L, Murphy D, Venneti S, Hameed M, Pawel BR, Wunder JS, Dickson BC, Lundgren SM, Jani KS, De Jay N, Papillon-Cavanagh S, Andrulis IL, Sawyer SL, Grynspan D, Turcotte RE, Nadaf J, Fahiminiyah S, Muir TW, Majewski J, Thompson CB, Chi P, Garcia BA, Allis CD, Jabado N, Lewis PW.

Science. 2016 May 13;352(6287):844-9. doi: 10.1126/science.aac7272.

4.

Characterization of H3.3K36M as a tool to study H3K36 methylation in cancer cells.

Sankaran SM, Gozani O.

Epigenetics. 2017;12(11):917-922. doi: 10.1080/15592294.2017.1377870. Epub 2017 Dec 11.

5.

Histone 3 lysine 36 to methionine mutations stably interact with and sequester SDG8 in Arabidopsis thaliana.

Lin G, Zhou Y, Li M, Fang Y.

Sci China Life Sci. 2018 Feb;61(2):225-234. doi: 10.1007/s11427-017-9162-1. Epub 2017 Sep 26.

PMID:
28975546
6.

Histone H3.3 G34 Mutations Alter Histone H3K36 and H3K27 Methylation In Cis.

Shi L, Shi J, Shi X, Li W, Wen H.

J Mol Biol. 2018 May 25;430(11):1562-1565. doi: 10.1016/j.jmb.2018.04.014. Epub 2018 Apr 22.

7.

Histone methyltransferase MMSET/NSD2 alters EZH2 binding and reprograms the myeloma epigenome through global and focal changes in H3K36 and H3K27 methylation.

Popovic R, Martinez-Garcia E, Giannopoulou EG, Zhang Q, Zhang Q, Ezponda T, Shah MY, Zheng Y, Will CM, Small EC, Hua Y, Bulic M, Jiang Y, Carrara M, Calogero RA, Kath WL, Kelleher NL, Wang JP, Elemento O, Licht JD.

PLoS Genet. 2014 Sep 4;10(9):e1004566. doi: 10.1371/journal.pgen.1004566. eCollection 2014 Sep.

8.

Mutation Analysis of H3F3A and H3F3B as a Diagnostic Tool for Giant Cell Tumor of Bone and Chondroblastoma.

Cleven AH, Höcker S, Briaire-de Bruijn I, Szuhai K, Cleton-Jansen AM, Bovée JV.

Am J Surg Pathol. 2015 Nov;39(11):1576-83. doi: 10.1097/PAS.0000000000000512.

PMID:
26457357
9.

Depletion of Nsd2-mediated histone H3K36 methylation impairs adipose tissue development and function.

Zhuang L, Jang Y, Park YK, Lee JE, Jain S, Froimchuk E, Broun A, Liu C, Gavrilova O, Ge K.

Nat Commun. 2018 May 4;9(1):1796. doi: 10.1038/s41467-018-04127-6.

10.

Histone Lysine-to-Methionine Mutations Reduce Histone Methylation and Cause Developmental Pleiotropy.

Sanders D, Qian S, Fieweger R, Lu L, Dowell JA, Denu JM, Zhong X.

Plant Physiol. 2017 Apr;173(4):2243-2252. doi: 10.1104/pp.16.01499. Epub 2017 Feb 15.

11.

Cancer-driving H3G34V/R/D mutations block H3K36 methylation and H3K36me3-MutSα interaction.

Fang J, Huang Y, Mao G, Yang S, Rennert G, Gu L, Li H, Li GM.

Proc Natl Acad Sci U S A. 2018 Sep 18;115(38):9598-9603. doi: 10.1073/pnas.1806355115. Epub 2018 Sep 4.

12.

Histone H3 lysine 9 and H4 lysine 20 trimethylation and the expression of Suv4-20h2 and Suv-39h1 histone methyltransferases in hepatocarcinogenesis induced by methyl deficiency in rats.

Pogribny IP, Ross SA, Tryndyak VP, Pogribna M, Poirier LA, Karpinets TV.

Carcinogenesis. 2006 Jun;27(6):1180-6. Epub 2006 Feb 23.

PMID:
16497704
13.

Molecular basis for oncohistone H3 recognition by SETD2 methyltransferase.

Yang S, Zheng X, Lu C, Li GM, Allis CD, Li H.

Genes Dev. 2016 Jul 15;30(14):1611-6. doi: 10.1101/gad.284323.116.

14.

Cancer-associated upregulation of histone H3 lysine 9 trimethylation promotes cell motility in vitro and drives tumor formation in vivo.

Yokoyama Y, Hieda M, Nishioka Y, Matsumoto A, Higashi S, Kimura H, Yamamoto H, Mori M, Matsuura S, Matsuura N.

Cancer Sci. 2013 Jul;104(7):889-95. doi: 10.1111/cas.12166. Epub 2013 May 15.

15.

Structure/Function Analysis of Recurrent Mutations in SETD2 Protein Reveals a Critical and Conserved Role for a SET Domain Residue in Maintaining Protein Stability and Histone H3 Lys-36 Trimethylation.

Hacker KE, Fahey CC, Shinsky SA, Chiang YJ, DiFiore JV, Jha DK, Vo AH, Shavit JA, Davis IJ, Strahl BD, Rathmell WK.

J Biol Chem. 2016 Sep 30;291(40):21283-21295. Epub 2016 Aug 15.

16.

Molecular basis for the role of oncogenic histone mutations in modulating H3K36 methylation.

Zhang Y, Shan CM, Wang J, Bao K, Tong L, Jia S.

Sci Rep. 2017 Mar 3;7:43906. doi: 10.1038/srep43906.

17.

SETD2-dependent histone H3K36 trimethylation is required for homologous recombination repair and genome stability.

Pfister SX, Ahrabi S, Zalmas LP, Sarkar S, Aymard F, Bachrati CZ, Helleday T, Legube G, La Thangue NB, Porter AC, Humphrey TC.

Cell Rep. 2014 Jun 26;7(6):2006-18. doi: 10.1016/j.celrep.2014.05.026. Epub 2014 Jun 12.

18.

The H3F3 K36M mutant antibody is a sensitive and specific marker for the diagnosis of chondroblastoma.

Amary MF, Berisha F, Mozela R, Gibbons R, Guttridge A, O'Donnell P, Baumhoer D, Tirabosco R, Flanagan AM.

Histopathology. 2016 Jul;69(1):121-7. doi: 10.1111/his.12945. Epub 2016 Mar 21.

PMID:
26844533
19.

SETD2-dependent H3K36me3 plays a critical role in epigenetic regulation of the HPV31 life cycle.

Gautam D, Johnson BA, Mac M, Moody CA.

PLoS Pathog. 2018 Oct 12;14(10):e1007367. doi: 10.1371/journal.ppat.1007367. eCollection 2018 Oct.

20.

H3F3 mutation status of giant cell tumors of the bone, chondroblastomas and their mimics: a combined high resolution melting and pyrosequencing approach.

Kervarrec T, Collin C, Larousserie F, Bouvier C, Aubert S, Gomez-Brouchet A, Marie B, Miquelestorena-Standley E, Le Nail LR, Avril P, Christophe Pagès J, de Pinieux G.

Mod Pathol. 2017 Mar;30(3):393-406. doi: 10.1038/modpathol.2016.212. Epub 2017 Jan 6.

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