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27210827,20944638,24168260,31862407,28656296,25575522,29990483,24599018,25766467,27449068,19015603,27592222,24379178,17345786,28442323,25339158,22497476,31629013,22665126,16505206,33455985,31023080,10854085,24756097,21946695,18497476,17098828,18849338,22120037,26144375,20357030,9609089,26386115,20703229,29155324,25194138,19793108,18785976,17903697,25650385,19808375,23762470,10417395,28940861,26886190,10615411,30634441,15897343,24169251,17496209,17049503,24842388,22508831,24429674,28822808,19139606,22460555,26883384,22561449,23291307,22811473,22326534,33070664,23873801,20528771,28091615,24858078,19461648,24067190,29081650,28758593,16157793,32184813,12184061,20580688,30124209,18845809,18418273,24699426,29196099,20833959,31720995,32476477,25806688,27085714,25973029,29691582,30369568,31273339,23188126,32089050,19665690,27469342,27612496,22921883,24332999,14551246,17880376,19927151,22715807,15539634,29516284,12270869,24814023,31339773,29335866,27050934,23592774,21845858,16766648,20581171,24219285,18252761,23459599,29995907,28758595,10373224,30421564,12452330,33007385,25644821,24813328,28669009,27815252,26029927,25089563,32971570,17906098,27496559,7492986,33394361,21699940,23736127,21952934,27374118,11514383,12154108,28536469,29923351,31165585,25225202,30602301,18703536,26715125,18557800,23349663,29052864,32380079,29969931,29073623,25151897,26648693,34357376,12431448,24859374,36871666,18046542,25175177,22595130,15228092,9321751,30370429,23823602,17416596,18495827,28619367,29329358,28082260,15117851,31116771,15833808,28371822,35126818,29926608,29119534,27480833,33390039,30246378,18403595,28287886,29969996,18419956,30850299,27110876,35515386,22474255,9950833,28799247,29086247,33577434,9118530,31805278,23868934,19662023,22947377,21927577,21638102,29351514,14615287,21173078,18800459,16176966,28791402,31401939,23043153,31820314,23942780,21756232,15894569,26420325,11181478,21963897,17308000,29464572,18258853,29676239,27483989,18414380,27660028,25724492,17572702,29620193,16774988,12215461,30249396,10750588,16598165,19995939,10588088,21188549,17255372,20375118,19124678,28842434,27382769,8831515,18676690,19073907,19698082,19779471,26378790,15998712,9302358,21376054,19597528,28039944,18783396,12623134,24215514,22558183,34704526,30466089,32730701,17483239,20411619,10487332,27796324,28192475,9727021,28648738,18800451,31361702,25089522,29443552,18948167,23176212,23176220,21824992,32585603,28888034,24740791,20676968,28659552,18417209,11788460,21045683,29262413,30267750,32943375,25620630,23029101,9562437,31396758,20810609,24028210,28973481,31178725,23636094,31042418,25924878,34282828,15951342,14871031,25947168,27955986,15010278,24627703,9788827,27715254,24444314,11457756,32362932,35288835,17085538,21881224,23155428,21091432,31643954,30055537,18032521,28970203,14678229,33390770,10076920,19202318,23628010,32522899,28295363,33568793,28337024,31898578,29884907,18553176,30412790,21611889,32040481,28596676,11560859,24728465,30092004,12431444,33684388,34944046,33200795,35697767,29682889,19721329,28928410,29178049,23755216,18583318,19303904,30664842,32087363,19946038,28160049,29455433,19429818,17666345,22462736,29266779,31346990,30053525,16501302,21147120,28239158,24416421,1338563,28464037,20837888,20308802,17644572,31612078,24877125,10076178,28186543,15638745,35730615,24898407,26010093,24260317,10750587,24466104,28374982,30341569,34576047,9851965,28661206,30227249,30369577,31854513,31376367,10669640,31484552,34757002,17572701,29232407,23937445,24586922,29368003,10205143,30557497,16565312,35178990,14751847,28321644,26919721,9843462,29928987,16598172,28833476,35749941,29860395,18654024,16100249,10420393,11683476,31642813,33657051,20178811,23603931,7843775,9420636,28708271,10419059,30868173,32580159,25795458,24614802,31496651,25122644,31928110,33301800,20801892,15879491,24662196,11904534,28812967,24102099,30193956,31436351,28461606,17586619,27941178,31868144,24614509,21665960,18660448,15662225,29431106,27558087,29359665,29470359,27773659,35222798,28461455,19923158,9833170,27239047,20724490,25345602,28034895,29626503,25164083,33416459,31506648,24161906,21900645,35269547,34565075,12680847,36674423,11788426,24425501,9362317,34147480,22538956,18391105,20563831,7805197,10444486,22497828,19846569,30521107,11016481,30839510,35794561,14693687,26240115,21818582,20097717,25496380,30204779,35907209,11465912,34646427,9362249,21818366,33014281,26828783,19955853,32504066,24384547,18536757,22438854,36370010,35231451,28040266,27080540,20204277,29752040,17827781,32604999,31155290,28889965,26485988,23687144,32675749,32103002,30988133,36907262,32531678,29514257,25664248,29120957,24416343,32039680,34356603,27986659,27143353,17416604,36359731,23389452,31803758,10639182,24490814,10967201,19126686,23712358,24177423,20534773,24858848,33736980,32106379,34622460,26303226,16755007,21183740,23538211,33526381,32122211,17977919,22972902,36270538,29566148,12393091,25613478,23840884,20029960,20937029,20722567,30822355,32294475,31536826,31955888,19120129,19917877,825263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The effects of different angiotensin II type 1 receptor blockers on the regulation of the ACE-AngII-AT1 and ACE2-Ang(1-7)-Mas axes in pressure overload-induced cardiac remodeling in male mice.

Wang X, Ye Y, Gong H, Wu J, Yuan J, Wang S, Yin P, Ding Z, Kang L, Jiang Q, Zhang W, Li Y, Ge J, Zou Y. Wang X, et al. J Mol Cell Cardiol. 2016 Aug;97:180-90. doi: 10.1016/j.yjmcc.2016.05.012. Epub 2016 May 19. J Mol Cell Cardiol. 2016. PMID: 27210827

Comparison of angiotensin II type 1-receptor blockers to regress pressure overload-induced cardiac hypertrophy in mice.

Li L, Zhou N, Gong H, Wu J, Lin L, Komuro I, Ge J, Zou Y. Li L, et al. Hypertens Res. 2010 Dec;33(12):1289-97. doi: 10.1038/hr.2010.182. Epub 2010 Oct 14. Hypertens Res. 2010. PMID: 20944638

Angiotensin-converting enzyme 2/angiotensin-(1-7)/Mas axis protects against lung fibrosis by inhibiting the MAPK/NF-κB pathway.

Meng Y, Yu CH, Li W, Li T, Luo W, Huang S, Wu PS, Cai SX, Li X. Meng Y, et al. Am J Respir Cell Mol Biol. 2014 Apr;50(4):723-36. doi: 10.1165/rcmb.2012-0451OC. Am J Respir Cell Mol Biol. 2014. PMID: 24168260

Tsantan Sumtang attenuated chronic hypoxia-induced right ventricular structure remodeling and fibrosis by equilibrating local ACE-AngII-AT1R/ACE2-Ang1-7-Mas axis in rat.

Dang Z, Su S, Jin G, Nan X, Ma L, Li Z, Lu D, Ge R. Dang Z, et al. J Ethnopharmacol. 2020 Mar 25;250:112470. doi: 10.1016/j.jep.2019.112470. Epub 2019 Dec 17. J Ethnopharmacol. 2020. PMID: 31862407

The ACE2-Ang (1-7)-Mas receptor axis attenuates cardiac remodeling and fibrosis in post-myocardial infarction.

Wang J, He W, Guo L, Zhang Y, Li H, Han S, Shen D. Wang J, et al. Mol Med Rep. 2017 Aug;16(2):1973-1981. doi: 10.3892/mmr.2017.6848. Epub 2017 Jun 23. Mol Med Rep. 2017. PMID: 28656296 Free PMC article.

Alteration of cardiac ACE2/Mas expression and cardiac remodelling in rats with aortic constriction.

Zhang Y, Li B, Wang B, Zhang J, Wu J, Morgan T. Zhang Y, et al. Chin J Physiol. 2014 Dec 31;57(6):335-42. doi: 10.4077/CJP.2014.BAD268. Chin J Physiol. 2014. PMID: 25575522

Sini decoction alleviates E. coli induced acute lung injury in mice via equilibrating ACE-AngII-AT1R and ACE2-Ang-(1-7)-Mas axis.

Liu J, Chen Q, Liu S, Yang X, Zhang Y, Huang F. Liu J, et al. Life Sci. 2018 Sep 1;208:139-148. doi: 10.1016/j.lfs.2018.07.013. Epub 2018 Jul 7. Life Sci. 2018. PMID: 29990483

Role of angiotensin-converting enzyme 2/angiotensin-(1-7)/Mas axis in the hypotensive effect of azilsartan.

Iwanami J, Mogi M, Tsukuda K, Wang XL, Nakaoka H, Ohshima K, Chisaka T, Bai HY, Kanno H, Min LJ, Horiuchi M. Iwanami J, et al. Hypertens Res. 2014 Jul;37(7):616-20. doi: 10.1038/hr.2014.49. Epub 2014 Mar 6. Hypertens Res. 2014. PMID: 24599018

Perinatally administered losartan augments renal ACE2 expression but not cardiac or renal Mas receptor in spontaneously hypertensive rats.

Klimas J, Olvedy M, Ochodnicka-Mackovicova K, Kruzliak P, Cacanyiova S, Kristek F, Krenek P, Ochodnicky P. Klimas J, et al. J Cell Mol Med. 2015 Aug;19(8):1965-74. doi: 10.1111/jcmm.12573. Epub 2015 Mar 12. J Cell Mol Med. 2015. PMID: 25766467 Free PMC article.

Captopril improves postresuscitation hemodynamics protective against pulmonary embolism by activating the ACE2/Ang-(1-7)/Mas axis.

Xiao HL, Li CS, Zhao LX, Yang J, Tong N, An L, Liu QT. Xiao HL, et al. Naunyn Schmiedebergs Arch Pharmacol. 2016 Nov;389(11):1159-1169. doi: 10.1007/s00210-016-1278-7. Epub 2016 Jul 22. Naunyn Schmiedebergs Arch Pharmacol. 2016. PMID: 27449068

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