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Items: 1 to 20 of 102

1.

Aberrant Calreticulin Expression in Articular Cartilage of Dio2 Deficient Mice.

Bomer N, Cornelis FM, Ramos YF, den Hollander W, Lakenberg N, van der Breggen R, Storms L, Slagboom PE, Lories RJ, Meulenbelt I.

PLoS One. 2016 May 10;11(5):e0154999. doi: 10.1371/journal.pone.0154999. eCollection 2016.

2.

The effect of forced exercise on knee joints in Dio2(-/-) mice: type II iodothyronine deiodinase-deficient mice are less prone to develop OA-like cartilage damage upon excessive mechanical stress.

Bomer N, Cornelis FM, Ramos YF, den Hollander W, Storms L, van der Breggen R, Lakenberg N, Slagboom PE, Meulenbelt I, Lories RJ.

Ann Rheum Dis. 2016 Mar;75(3):571-7. doi: 10.1136/annrheumdis-2014-206608. Epub 2014 Dec 30.

PMID:
25550340
3.

Deiodinase 2 upregulation demonstrated in osteoarthritis patients cartilage causes cartilage destruction in tissue-specific transgenic rats.

Nagase H, Nagasawa Y, Tachida Y, Sakakibara S, Okutsu J, Suematsu N, Arita S, Shimada K.

Osteoarthritis Cartilage. 2013 Mar;21(3):514-23. doi: 10.1016/j.joca.2012.12.013. Epub 2013 Jan 4.

4.

Genetic inhibition of fibroblast growth factor receptor 1 in knee cartilage attenuates the degeneration of articular cartilage in adult mice.

Weng T, Yi L, Huang J, Luo F, Wen X, Du X, Chen Q, Deng C, Chen D, Chen L.

Arthritis Rheum. 2012 Dec;64(12):3982-92. doi: 10.1002/art.34645.

5.

Underlying molecular mechanisms of DIO2 susceptibility in symptomatic osteoarthritis.

Bomer N, den Hollander W, Ramos YF, Bos SD, van der Breggen R, Lakenberg N, Pepers BA, van Eeden AE, Darvishan A, Tobi EW, Duijnisveld BJ, van den Akker EB, Heijmans BT, van Roon-Mom WM, Verbeek FJ, van Osch GJ, Nelissen RG, Slagboom PE, Meulenbelt I.

Ann Rheum Dis. 2015 Aug;74(8):1571-9. doi: 10.1136/annrheumdis-2013-204739. Epub 2014 Apr 2.

6.

Regional differences of tibial and femoral cartilage in the chondrocyte gene expression, immunhistochemistry and composite in different stages of osteoarthritis.

Lahm A, Dabravolski D, Spank H, Merk H, Esser J, Kasch R.

Tissue Cell. 2017 Apr;49(2 Pt B):249-256. doi: 10.1016/j.tice.2017.02.004. Epub 2017 Feb 24.

PMID:
28302318
7.

CCN family member 2/connective tissue growth factor (CCN2/CTGF) has anti-aging effects that protect articular cartilage from age-related degenerative changes.

Itoh S, Hattori T, Tomita N, Aoyama E, Yutani Y, Yamashiro T, Takigawa M.

PLoS One. 2013 Aug 12;8(8):e71156. doi: 10.1371/journal.pone.0071156. eCollection 2013.

8.

Downregulation of microRNA-448 inhibits IL-1β-induced cartilage degradation in human chondrocytes via upregulation of matrilin-3.

Yang H, Wu D, Li H, Chen N, Shang Y.

Cell Mol Biol Lett. 2018 Feb 22;23:7. doi: 10.1186/s11658-018-0072-6. eCollection 2018.

10.

Tight regulation of wingless-type signaling in the articular cartilage - subchondral bone biomechanical unit: transcriptomics in Frzb-knockout mice.

Lodewyckx L, Cailotto F, Thysen S, Luyten FP, Lories RJ.

Arthritis Res Ther. 2012 Jan 20;14(1):R16. doi: 10.1186/ar3695.

11.

Prenatal caffeine exprosure increases adult female offspring rat's susceptibility to osteoarthritis via low-functional programming of cartilage IGF-1 with histone acetylation.

Tan Y, Lu K, Li J, Ni Q, Zhao Z, Magdalou J, Chen L, Wang H.

Toxicol Lett. 2018 Oct 1;295:229-236. doi: 10.1016/j.toxlet.2018.06.1221. Epub 2018 Jun 30.

PMID:
29966748
12.

Metabolic activity and gene expression of osteoarthritic chondrocytes in correlation with radiological and histological characteristics.

Stöve J, Gremmes C, Günther KP, Scharf HP, Schwarz M.

Biomed Pharmacother. 2006 Dec;60(10):644-7. Epub 2006 Oct 24.

PMID:
17064871
13.

Similar properties of chondrocytes from osteoarthritis joints and mesenchymal stem cells from healthy donors for tissue engineering of articular cartilage.

Fernandes AM, Herlofsen SR, Karlsen TA, Küchler AM, Fløisand Y, Brinchmann JE.

PLoS One. 2013 May 9;8(5):e62994. doi: 10.1371/journal.pone.0062994. Print 2013.

14.

Brief Report: JNK-2 Controls Aggrecan Degradation in Murine Articular Cartilage and the Development of Experimental Osteoarthritis.

Ismail HM, Miotla-Zarebska J, Troeberg L, Tang X, Stott B, Yamamoto K, Nagase H, Fosang AJ, Vincent TL, Saklatvala J.

Arthritis Rheumatol. 2016 May;68(5):1165-71. doi: 10.1002/art.39547.

15.

Differential expression of GADD45beta in normal and osteoarthritic cartilage: potential role in homeostasis of articular chondrocytes.

Ijiri K, Zerbini LF, Peng H, Otu HH, Tsuchimochi K, Otero M, Dragomir C, Walsh N, Bierbaum BE, Mattingly D, van Flandern G, Komiya S, Aigner T, Libermann TA, Goldring MB.

Arthritis Rheum. 2008 Jul;58(7):2075-87. doi: 10.1002/art.23504.

16.

Cartilage-specific deletion of Alk5 gene results in a progressive osteoarthritis-like phenotype in mice.

Wang Q, Tan QY, Xu W, Qi HB, Chen D, Zhou S, Ni ZH, Kuang L, Guo JY, Huang JL, Wang XX, Wang ZQ, Su N, Chen L, Chen B, Jiang WL, Gao Y, Chen HG, Du XL, Xie YL, Chen L.

Osteoarthritis Cartilage. 2017 Nov;25(11):1868-1879. doi: 10.1016/j.joca.2017.07.010. Epub 2017 Jul 14.

17.

Depletion of protease-activated receptor 2 but not protease-activated receptor 1 may confer protection against osteoarthritis in mice through extracartilaginous mechanisms.

Jackson MT, Moradi B, Zaki S, Smith MM, McCracken S, Smith SM, Jackson CJ, Little CB.

Arthritis Rheumatol. 2014 Dec;66(12):3337-48. doi: 10.1002/art.38876.

18.

Berberine ameliorates cartilage degeneration in interleukin-1β-stimulated rat chondrocytes and in a rat model of osteoarthritis via Akt signalling.

Zhao H, Zhang T, Xia C, Shi L, Wang S, Zheng X, Hu T, Zhang B.

J Cell Mol Med. 2014 Feb;18(2):283-92. doi: 10.1111/jcmm.12186. Epub 2013 Nov 28.

19.

Disturbed cartilage and joint homeostasis resulting from a loss of mitogen-inducible gene 6 in a mouse model of joint dysfunction.

Pest MA, Russell BA, Zhang YW, Jeong JW, Beier F.

Arthritis Rheumatol. 2014 Oct;66(10):2816-27. doi: 10.1002/art.38758.

20.

Matrix metalloproteinase 13-deficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development.

Little CB, Barai A, Burkhardt D, Smith SM, Fosang AJ, Werb Z, Shah M, Thompson EW.

Arthritis Rheum. 2009 Dec;60(12):3723-33. doi: 10.1002/art.25002.

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