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Items: 1 to 20 of 83

1.

Cyp3a deficiency enhances androgen receptor activity and cholesterol synthesis in the mouse prostate.

Hashimoto M, Kobayashi K, Yamazaki M, Kazuki Y, Takehara S, Oshimura M, Chiba K.

J Steroid Biochem Mol Biol. 2016 Oct;163:121-8. doi: 10.1016/j.jsbmb.2016.04.018. Epub 2016 Apr 29.

PMID:
27137100
2.

Knockout of mouse Cyp3a gene enhances synthesis of cholesterol and bile acid in the liver.

Hashimoto M, Kobayashi K, Watanabe M, Kazuki Y, Takehara S, Inaba A, Nitta S, Senda N, Oshimura M, Chiba K.

J Lipid Res. 2013 Aug;54(8):2060-8. doi: 10.1194/jlr.M033464. Epub 2013 May 24.

3.

SCAP/SREBP pathway is required for the full steroidogenic response to cyclic AMP.

Shimizu-Albergine M, Van Yserloo B, Golkowski MG, Ong SE, Beavo JA, Bornfeldt KE.

Proc Natl Acad Sci U S A. 2016 Sep 20;113(38):E5685-93. doi: 10.1073/pnas.1611424113. Epub 2016 Sep 6.

4.

Anti-epileptic drug phenytoin enhances androgen metabolism and androgen receptor expression in murine hippocampus.

Meyer RP, Hagemeyer CE, Knoth R, Kaufmann MR, Volk B.

J Neurochem. 2006 Jan;96(2):460-72. Epub 2005 Nov 29.

5.

Antiepileptic drugs affect neuronal androgen signaling via a cytochrome P450-dependent pathway.

Gehlhaus M, Schmitt N, Volk B, Meyer RP.

J Pharmacol Exp Ther. 2007 Aug;322(2):550-9. Epub 2007 May 15.

PMID:
17505019
6.

Regulated expression of the prostacyclin receptor (IP) gene by androgens within the vasculature: Combined role for androgens and serum cholesterol.

Eivers SB, Kinsella BT.

Biochim Biophys Acta. 2016 Oct;1859(10):1333-51. doi: 10.1016/j.bbagrm.2016.06.011. Epub 2016 Jun 27.

PMID:
27365208
7.

Cross-talk between TLR4-MyD88-NF-κB and SCAP-SREBP2 pathways mediates macrophage foam cell formation.

Li LC, Varghese Z, Moorhead JF, Lee CT, Chen JB, Ruan XZ.

Am J Physiol Heart Circ Physiol. 2013 Mar 15;304(6):H874-84. doi: 10.1152/ajpheart.00096.2012. Epub 2013 Jan 18.

8.

The nuclear receptor FXR uncouples the actions of miR-33 from SREBP-2.

Tarling EJ, Ahn H, de Aguiar Vallim TQ.

Arterioscler Thromb Vasc Biol. 2015 Apr;35(4):787-95. doi: 10.1161/ATVBAHA.114.304179. Epub 2015 Jan 15.

9.

Activation of CYP3A-mediated testosterone 6β-hydroxylation by tanshinone IIA and midazolam 1-hydroxylation by cryptotanshinone in human liver microsomes.

Qiu F, Zhang R, Wang G, Gao C, Sun J, Jiang J, Ma Y.

Xenobiotica. 2010 Dec;40(12):800-6. doi: 10.3109/00498254.2010.519062. Epub 2010 Oct 22.

PMID:
20964620
10.

Overexpression of A-kinase anchoring protein 12A activates sterol regulatory element binding protein-2 and enhances cholesterol efflux in hepatic cells.

Choi MC, Lee YU, Kim SH, Lee JH, Park JH, Streb JW, Oh DY, Im SA, Kim TY, Jong HS, Bang YJ.

Int J Biochem Cell Biol. 2008;40(11):2534-43. doi: 10.1016/j.biocel.2008.04.020. Epub 2008 May 20.

PMID:
18579430
11.

Cross-talk between the androgen receptor and the liver X receptor: implications for cholesterol homeostasis.

Krycer JR, Brown AJ.

J Biol Chem. 2011 Jun 10;286(23):20637-47. doi: 10.1074/jbc.M111.227082. Epub 2011 Apr 13.

12.

Concordant up-regulation of cytochrome P450 Cyp3a11, testosterone oxidation and androgen receptor expression in mouse brain after xenobiotic treatment.

Meyer RP, Gehlhaus M, Schwab R, Bürck C, Knoth R, Hagemeyer CE.

J Neurochem. 2009 Apr;109(2):670-81. doi: 10.1111/j.1471-4159.2009.05994.x. Epub 2009 Feb 16.

13.

Control of cholesterol biosynthesis, uptake and storage in hepatocytes by Cideb.

Li JZ, Lei Y, Wang Y, Zhang Y, Ye J, Xia X, Pan X, Li P.

Biochim Biophys Acta. 2010 May;1801(5):577-86. doi: 10.1016/j.bbalip.2010.01.012. Epub 2010 Feb 1.

PMID:
20123130
15.

Difference in LDL receptor feedback regulation in macrophages and vascular smooth muscle cells: foam cell transformation under inflammatory stress.

Ye Q, Lei H, Fan Z, Zheng W, Zheng S.

Inflammation. 2014 Apr;37(2):555-65. doi: 10.1007/s10753-013-9769-x.

PMID:
24297394
16.

Lipid disorder and intrahepatic renin-angiotensin system activation synergistically contribute to non-alcoholic fatty liver disease.

Wu Y, Ma KL, Zhang Y, Wen Y, Wang GH, Hu ZB, Liu L, Lu J, Chen PP, Ruan XZ, Liu BC.

Liver Int. 2016 Oct;36(10):1525-34. doi: 10.1111/liv.13131. Epub 2016 May 3.

PMID:
27028410
17.

Identification of the C-terminal domain of Daxx acts as a potential regulator of intracellular cholesterol synthesis in HepG2 cells.

Sun S, Wen J, Qiu F, Yin Y, Xu G, Li T, Nie J, Xiong G, Zhang C, Liao D, Chen J, Tuo Q.

Biochem Biophys Res Commun. 2016 Nov 4;480(1):139-145. doi: 10.1016/j.bbrc.2016.09.102. Epub 2016 Sep 23.

PMID:
27671201
18.

Regulation of constitutive mouse hepatic cytochromes P450 and growth hormone signaling components by 3-methylcholanthrene.

Lee C, Hutson JR, Tzau VK, Riddick DS.

Drug Metab Dispos. 2006 Sep;34(9):1530-8. Epub 2006 Jun 16.

PMID:
16782765
19.

Effect of deficiency in SREBP cleavage-activating protein on lipid metabolism during intermittent hypoxia.

Li J, Nanayakkara A, Jun J, Savransky V, Polotsky VY.

Physiol Genomics. 2007 Oct 22;31(2):273-80. Epub 2007 Jul 31.

PMID:
17666524
20.

Overexpression of a key regulator of lipid homeostasis, Scap, promotes respiration in prostate cancer cells.

Prabhu AV, Krycer JR, Brown AJ.

FEBS Lett. 2013 Apr 2;587(7):983-8. doi: 10.1016/j.febslet.2013.02.040. Epub 2013 Feb 27.

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