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Identification of chemicals that mimic transcriptional changes associated with autism, brain aging and neurodegeneration.

Pearson BL, Simon JM, McCoy ES, Salazar G, Fragola G, Zylka MJ.

Nat Commun. 2016 Mar 31;7:11173. doi: 10.1038/ncomms11173.


Emerging neurotoxic mechanisms in environmental factors-induced neurodegeneration.

Kanthasamy A, Jin H, Anantharam V, Sondarva G, Rangasamy V, Rana A, Kanthasamy A.

Neurotoxicology. 2012 Aug;33(4):833-7. doi: 10.1016/j.neuro.2012.01.011. Epub 2012 Feb 7.


Biochemical and toxicological evidence of neurological effects of pesticides: the example of Parkinson's disease.

Moretto A, Colosio C.

Neurotoxicology. 2011 Aug;32(4):383-91. doi: 10.1016/j.neuro.2011.03.004. Epub 2011 Mar 23. Review.


Pesticides exposure as etiological factors of Parkinson's disease and other neurodegenerative diseases--a mechanistic approach.

Baltazar MT, Dinis-Oliveira RJ, de Lourdes Bastos M, Tsatsakis AM, Duarte JA, Carvalho F.

Toxicol Lett. 2014 Oct 15;230(2):85-103. doi: 10.1016/j.toxlet.2014.01.039. Epub 2014 Feb 3. Review.


[Neurotoxicity of pesticides: its relationship with neurodegenerative diseases].

Thany SH, Reynier P, Lenaers G.

Med Sci (Paris). 2013 Mar;29(3):273-8. doi: 10.1051/medsci/2013293013. Epub 2013 Mar 27. French.


Environmental factors as modulators of neurodegeneration: insights from gene-environment interactions in Huntington's disease.

Mo C, Hannan AJ, Renoir T.

Neurosci Biobehav Rev. 2015 May;52:178-92. doi: 10.1016/j.neubiorev.2015.03.003. Epub 2015 Mar 10. Review.


Environmental-induced oxidative stress in neurodegenerative disorders and aging.

Migliore L, Coppedè F.

Mutat Res. 2009 Mar 31;674(1-2):73-84. doi: 10.1016/j.mrgentox.2008.09.013. Epub 2008 Oct 5. Review.


Transcriptomic analysis of autistic brain reveals convergent molecular pathology.

Voineagu I, Wang X, Johnston P, Lowe JK, Tian Y, Horvath S, Mill J, Cantor RM, Blencowe BJ, Geschwind DH.

Nature. 2011 May 25;474(7351):380-4. doi: 10.1038/nature10110.


Association between environmental exposure to pesticides and neurodegenerative diseases.

Parrón T, Requena M, Hernández AF, Alarcón R.

Toxicol Appl Pharmacol. 2011 Nov 1;256(3):379-85. doi: 10.1016/j.taap.2011.05.006. Epub 2011 May 13.


Neurodegeneration of mouse nigrostriatal dopaminergic system induced by repeated oral administration of rotenone is prevented by 4-phenylbutyrate, a chemical chaperone.

Inden M, Kitamura Y, Takeuchi H, Yanagida T, Takata K, Kobayashi Y, Taniguchi T, Yoshimoto K, Kaneko M, Okuma Y, Taira T, Ariga H, Shimohama S.

J Neurochem. 2007 Jun;101(6):1491-1504.


JNK inhibition of VMAT2 contributes to rotenone-induced oxidative stress and dopamine neuron death.

Choi WS, Kim HW, Xia Z.

Toxicology. 2015 Feb 3;328:75-81. doi: 10.1016/j.tox.2014.12.005. Epub 2014 Dec 9.


Tipping the balance of autism risk: potential mechanisms linking pesticides and autism.

Shelton JF, Hertz-Picciotto I, Pessah IN.

Environ Health Perspect. 2012 Jul;120(7):944-51. doi: 10.1289/ehp.1104553. Epub 2012 Apr 25.


Combined exposure to Maneb and Paraquat alters transcriptional regulation of neurogenesis-related genes in mice models of Parkinson's disease.

Desplats P, Patel P, Kosberg K, Mante M, Patrick C, Rockenstein E, Fujita M, Hashimoto M, Masliah E.

Mol Neurodegener. 2012 Sep 28;7:49. doi: 10.1186/1750-1326-7-49.


Distinct role for microglia in rotenone-induced degeneration of dopaminergic neurons.

Gao HM, Hong JS, Zhang W, Liu B.

J Neurosci. 2002 Feb 1;22(3):782-90.


Nitric oxide and cellular stress response in brain aging and neurodegenerative disorders: the role of vitagenes.

Calabrese V, Boyd-Kimball D, Scapagnini G, Butterfield DA.

In Vivo. 2004 May-Jun;18(3):245-67. Review.


Proteomic identification of brain proteins in the canine model of human aging following a long-term treatment with antioxidants and a program of behavioral enrichment: relevance to Alzheimer's disease.

Opii WO, Joshi G, Head E, Milgram NW, Muggenburg BA, Klein JB, Pierce WM, Cotman CW, Butterfield DA.

Neurobiol Aging. 2008 Jan;29(1):51-70. Epub 2006 Oct 20.

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