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Items: 1 to 20 of 111


Pleiotropic effects of the vacuolar ABC transporter MLT1 of Candida albicans on cell function and virulence.

Khandelwal NK, Kaemmer P, Förster TM, Singh A, Coste AT, Andes DR, Hube B, Sanglard D, Chauhan N, Kaur R, d'Enfert C, Mondal AK, Prasad R.

Biochem J. 2016 Jun 1;473(11):1537-52. doi: 10.1042/BCJ20160024. Epub 2016 Mar 29.


Functional analysis of a vacuolar ABC transporter in wild-type Candida albicans reveals its involvement in virulence.

Theiss S, Kretschmar M, Nichterlein T, Hof H, Agabian N, Hacker J, Köhler GA.

Mol Microbiol. 2002 Feb;43(3):571-84.


ABC transporter Cdr1p contributes more than Cdr2p does to fluconazole efflux in fluconazole-resistant Candida albicans clinical isolates.

Holmes AR, Lin YH, Niimi K, Lamping E, Keniya M, Niimi M, Tanabe K, Monk BC, Cannon RD.

Antimicrob Agents Chemother. 2008 Nov;52(11):3851-62. doi: 10.1128/AAC.00463-08. Epub 2008 Aug 18.


Chimeras of Candida albicans Cdr1p and Cdr2p reveal features of pleiotropic drug resistance transporter structure and function.

Tanabe K, Lamping E, Nagi M, Okawada A, Holmes AR, Miyazaki Y, Cannon RD, Monk BC, Niimi M.

Mol Microbiol. 2011 Oct;82(2):416-33. doi: 10.1111/j.1365-2958.2011.07820.x. Epub 2011 Sep 19.


Reversal of antifungal resistance mediated by ABC efflux pumps from Candida albicans functionally expressed in yeast.

Schuetzer-Muehlbauer M, Willinger B, Egner R, Ecker G, Kuchler K.

Int J Antimicrob Agents. 2003 Sep;22(3):291-300.


ABC transporters Cdr1p, Cdr2p and Cdr3p of a human pathogen Candida albicans are general phospholipid translocators.

Smriti, Krishnamurthy S, Dixit BL, Gupta CM, Milewski S, Prasad R.

Yeast. 2002 Mar 15;19(4):303-18.


Azole resistance in a Candida albicans mutant lacking the ABC transporter CDR6/ROA1 depends on TOR signaling.

Khandelwal NK, Chauhan N, Sarkar P, Esquivel BD, Coccetti P, Singh A, Coste AT, Gupta M, Sanglard D, White TC, Chauvel M, d'Enfert C, Chattopadhyay A, Gaur NA, Mondal AK, Prasad R.

J Biol Chem. 2018 Jan 12;293(2):412-432. doi: 10.1074/jbc.M117.807032. Epub 2017 Nov 20.


The Candida albicans Cdr2p ATP-binding cassette (ABC) transporter confers resistance to caspofungin.

Schuetzer-Muehlbauer M, Willinger B, Krapf G, Enzinger S, Presterl E, Kuchler K.

Mol Microbiol. 2003 Apr;48(1):225-35.


Rationally designed transmembrane peptide mimics of the multidrug transporter protein Cdr1 act as antagonists to selectively block drug efflux and chemosensitize azole-resistant clinical isolates of Candida albicans.

Maurya IK, Thota CK, Verma SD, Sharma J, Rawal MK, Ravikumar B, Sen S, Chauhan N, Lynn AM, Chauhan VS, Prasad R.

J Biol Chem. 2013 Jun 7;288(23):16775-87. doi: 10.1074/jbc.M113.467159. Epub 2013 Apr 16.


The quorum-sensing molecule farnesol is a modulator of drug efflux mediated by ABC multidrug transporters and synergizes with drugs in Candida albicans.

Sharma M, Prasad R.

Antimicrob Agents Chemother. 2011 Oct;55(10):4834-43. doi: 10.1128/AAC.00344-11. Epub 2011 Jul 18.


The monoamine oxidase A inhibitor clorgyline is a broad-spectrum inhibitor of fungal ABC and MFS transporter efflux pump activities which reverses the azole resistance of Candida albicans and Candida glabrata clinical isolates.

Holmes AR, Keniya MV, Ivnitski-Steele I, Monk BC, Lamping E, Sklar LA, Cannon RD.

Antimicrob Agents Chemother. 2012 Mar;56(3):1508-15. doi: 10.1128/AAC.05706-11. Epub 2011 Dec 27.


All about CDR transporters: Past, present, and future.

Prasad R, Balzi E, Banerjee A, Khandelwal NK.

Yeast. 2019 Apr;36(4):223-233. doi: 10.1002/yea.3356. Epub 2018 Oct 29. Review.


Positive regulation of the Candida albicans multidrug efflux pump Cdr1p function by phosphorylation of its N-terminal extension.

Tsao S, Weber S, Cameron C, Nehme D, Ahmadzadeh E, Raymond M.

J Antimicrob Chemother. 2016 Nov;71(11):3125-3134. Epub 2016 Jul 7.


Enhanced susceptibility to antifungal oligopeptides in yeast strains overexpressing ABC multidrug efflux pumps.

Wakiec R, Gabriel I, Prasad R, Becker JM, Payne JW, Milewski S.

Antimicrob Agents Chemother. 2008 Nov;52(11):4057-63. doi: 10.1128/AAC.01648-07. Epub 2008 Sep 15.


Candida albicans AGE3, the ortholog of the S. cerevisiae ARF-GAP-encoding gene GCS1, is required for hyphal growth and drug resistance.

Lettner T, Zeidler U, Gimona M, Hauser M, Breitenbach M, Bito A.

PLoS One. 2010 Aug 5;5(8):e11993. doi: 10.1371/journal.pone.0011993.


Functional similarities and differences between Candida albicans Cdr1p and Cdr2p transporters.

Gauthier C, Weber S, Alarco AM, Alqawi O, Daoud R, Georges E, Raymond M.

Antimicrob Agents Chemother. 2003 May;47(5):1543-54.


Relative contributions of the Candida albicans ABC transporters Cdr1p and Cdr2p to clinical azole resistance.

Tsao S, Rahkhoodaee F, Raymond M.

Antimicrob Agents Chemother. 2009 Apr;53(4):1344-52. doi: 10.1128/AAC.00926-08. Epub 2009 Feb 17.

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