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Items: 1 to 20 of 131

1.

Structural and Molecular Determinants of Membrane Binding by the HIV-1 Matrix Protein.

Mercredi PY, Bucca N, Loeliger B, Gaines CR, Mehta M, Bhargava P, Tedbury PR, Charlier L, Floquet N, Muriaux D, Favard C, Sanders CR, Freed EO, Marchant J, Summers MF.

J Mol Biol. 2016 Apr 24;428(8):1637-55. doi: 10.1016/j.jmb.2016.03.005. Epub 2016 Mar 16.

2.

HIV-1 Matrix Protein Interactions with tRNA: Implications for Membrane Targeting.

Gaines CR, Tkacik E, Rivera-Oven A, Somani P, Achimovich A, Alabi T, Zhu A, Getachew N, Yang AL, McDonough M, Hawkins T, Spadaro Z, Summers MF.

J Mol Biol. 2018 Jul 6;430(14):2113-2127. doi: 10.1016/j.jmb.2018.04.042. Epub 2018 May 9.

3.

Membrane Binding of HIV-1 Matrix Protein: Dependence on Bilayer Composition and Protein Lipidation.

Barros M, Heinrich F, Datta SAK, Rein A, Karageorgos I, Nanda H, Lösche M.

J Virol. 2016 Apr 14;90(9):4544-4555. doi: 10.1128/JVI.02820-15. Print 2016 May.

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5.

Trio engagement via plasma membrane phospholipids and the myristoyl moiety governs HIV-1 matrix binding to bilayers.

Vlach J, Saad JS.

Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3525-30. doi: 10.1073/pnas.1216655110. Epub 2013 Feb 11.

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7.

The matrix domain of the Gag protein from avian sarcoma virus contains a PI(4,5)P2-binding site that targets Gag to the cell periphery.

Watanabe SM, Medina GN, Eastep GN, Ghanam RH, Vlach J, Saad JS, Carter CA.

J Biol Chem. 2018 Dec 7;293(49):18841-18853. doi: 10.1074/jbc.RA118.003947. Epub 2018 Oct 11.

PMID:
30309982
8.

HIV-1 Gag protein can sense the cholesterol and acyl chain environment in model membranes.

Dick RA, Goh SL, Feigenson GW, Vogt VM.

Proc Natl Acad Sci U S A. 2012 Nov 13;109(46):18761-6. doi: 10.1073/pnas.1209408109. Epub 2012 Sep 24.

9.

Coarse-grained simulations of the HIV-1 matrix protein anchoring: revisiting its assembly on membrane domains.

Charlier L, Louet M, Chaloin L, Fuchs P, Martinez J, Muriaux D, Favard C, Floquet N.

Biophys J. 2014 Feb 4;106(3):577-85. doi: 10.1016/j.bpj.2013.12.019.

10.

Opposing mechanisms involving RNA and lipids regulate HIV-1 Gag membrane binding through the highly basic region of the matrix domain.

Chukkapalli V, Oh SJ, Ono A.

Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1600-5. doi: 10.1073/pnas.0908661107. Epub 2010 Jan 4.

11.

Molecular Determinants Directing HIV-1 Gag Assembly to Virus-Containing Compartments in Primary Macrophages.

Inlora J, Chukkapalli V, Bedi S, Ono A.

J Virol. 2016 Sep 12;90(19):8509-19. doi: 10.1128/JVI.01004-16. Print 2016 Oct 1.

12.

Inhibition of HIV-1 Gag-membrane interactions by specific RNAs.

Todd GC, Duchon A, Inlora J, Olson ED, Musier-Forsyth K, Ono A.

RNA. 2017 Mar;23(3):395-405. doi: 10.1261/rna.058453.116. Epub 2016 Dec 8.

13.

Structural basis for targeting avian sarcoma virus Gag polyprotein to the plasma membrane for virus assembly.

Vlach J, Eastep GN, Ghanam RH, Watanabe SM, Carter CA, Saad JS.

J Biol Chem. 2018 Dec 7;293(49):18828-18840. doi: 10.1074/jbc.RA118.003944. Epub 2018 Oct 11.

PMID:
30309983
14.

HIV-1 matrix-31 membrane binding peptide interacts differently with membranes containing PS vs. PI(4,5)P2.

O'Neil L, Andenoro K, Pagano I, Carroll L, Langer L, Dell Z, Perera D, Treece BW, Heinrich F, Lösche M, Nagle JF, Tristram-Nagle S.

Biochim Biophys Acta. 2016 Dec;1858(12):3071-3081. doi: 10.1016/j.bbamem.2016.09.010. Epub 2016 Sep 15.

15.

Structural basis for targeting HIV-1 Gag proteins to the plasma membrane for virus assembly.

Saad JS, Miller J, Tai J, Kim A, Ghanam RH, Summers MF.

Proc Natl Acad Sci U S A. 2006 Jul 25;103(30):11364-9. Epub 2006 Jul 13.

16.

Roles played by acidic lipids in HIV-1 Gag membrane binding.

Olety B, Ono A.

Virus Res. 2014 Nov 26;193:108-15. doi: 10.1016/j.virusres.2014.06.015. Epub 2014 Jul 3. Review.

17.

Point mutations in the HIV-1 matrix protein turn off the myristyl switch.

Saad JS, Loeliger E, Luncsford P, Liriano M, Tai J, Kim A, Miller J, Joshi A, Freed EO, Summers MF.

J Mol Biol. 2007 Feb 16;366(2):574-85. Epub 2006 Dec 1.

18.

Elucidating the mechanism by which compensatory mutations rescue an HIV-1 matrix mutant defective for gag membrane targeting and envelope glycoprotein incorporation.

Tedbury PR, Mercredi PY, Gaines CR, Summers MF, Freed EO.

J Mol Biol. 2015 Mar 27;427(6 Pt B):1413-1427. doi: 10.1016/j.jmb.2015.01.018. Epub 2015 Feb 7.

19.

Myristate exposure in the human immunodeficiency virus type 1 matrix protein is modulated by pH.

Fledderman EL, Fujii K, Ghanam RH, Waki K, Prevelige PE, Freed EO, Saad JS.

Biochemistry. 2010 Nov 9;49(44):9551-62. doi: 10.1021/bi101245j.

20.

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