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Items: 1 to 20 of 145

1.

Flavokawain B induced cytotoxicity in two breast cancer cell lines, MCF-7 and MDA-MB231 and inhibited the metastatic potential of MDA-MB231 via the regulation of several tyrosine kinases In vitro.

Abu N, Akhtar MN, Yeap SK, Lim KL, Ho WY, Abdullah MP, Ho CL, Omar AR, Ismail J, Alitheen NB.

BMC Complement Altern Med. 2016 Feb 27;16:86. doi: 10.1186/s12906-016-1046-8.

2.

Flavokawain A induces apoptosis in MCF-7 and MDA-MB231 and inhibits the metastatic process in vitro.

Abu N, Akhtar MN, Yeap SK, Lim KL, Ho WY, Zulfadli AJ, Omar AR, Sulaiman MR, Abdullah MP, Alitheen NB.

PLoS One. 2014 Oct 6;9(10):e105244. doi: 10.1371/journal.pone.0105244. eCollection 2014.

3.

The In Vitro and In Vivo Antiangiogenic Effects of Flavokawain B.

Rossette MC, Moraes DC, Sacramento EK, Romano-Silva MA, Carvalho JL, Gomes DA, Caldas H, Friedman E, Bastos-Rodrigues L, De Marco L.

Phytother Res. 2017 Oct;31(10):1607-1613. doi: 10.1002/ptr.5891. Epub 2017 Aug 17.

PMID:
28816367
4.

Flavokawain B, a kava chalcone, inhibits growth of human osteosarcoma cells through G2/M cell cycle arrest and apoptosis.

Ji T, Lin C, Krill LS, Eskander R, Guo Y, Zi X, Hoang BH.

Mol Cancer. 2013 Jun 10;12:55. doi: 10.1186/1476-4598-12-55.

5.

In vivo antitumor and antimetastatic effects of flavokawain B in 4T1 breast cancer cell-challenged mice.

Abu N, Mohamed NE, Yeap SK, Lim KL, Akhtar MN, Zulfadli AJ, Kee BB, Abdullah MP, Omar AR, Alitheen NB.

Drug Des Devel Ther. 2015 Mar 6;9:1401-17. doi: 10.2147/DDDT.S67976. eCollection 2015.

6.

Flavokawain B, a novel, naturally occurring chalcone, exhibits robust apoptotic effects and induces G2/M arrest of a uterine leiomyosarcoma cell line.

Eskander RN, Randall LM, Sakai T, Guo Y, Hoang B, Zi X.

J Obstet Gynaecol Res. 2012 Aug;38(8):1086-94. doi: 10.1111/j.1447-0756.2011.01841.x. Epub 2012 Apr 30.

7.

Design, Synthesis and Docking Studies of Flavokawain B Type Chalcones and Their Cytotoxic Effects on MCF-7 and MDA-MB-231 Cell Lines.

Abu Bakar A, Akhtar MN, Mohd Ali N, Yeap SK, Quah CK, Loh WS, Alitheen NB, Zareen S, Ul-Haq Z, Shah SAA.

Molecules. 2018 Mar 8;23(3). pii: E616. doi: 10.3390/molecules23030616.

8.

Evaluation of antioxidant and anticancer activity of extract and fractions of Nardostachys jatamansi DC in breast carcinoma.

Chaudhary S, Chandrashekar KS, Pai KS, Setty MM, Devkar RA, Reddy ND, Shoja MH.

BMC Complement Altern Med. 2015 Mar 10;15:50. doi: 10.1186/s12906-015-0563-1.

9.

Flavokawains A and B from kava (Piper methysticum) activate heat shock and antioxidant responses and protect against hydrogen peroxide-induced cell death in HepG2 hepatocytes.

Pinner KD, Wales CT, Gristock RA, Vo HT, So N, Jacobs AT.

Pharm Biol. 2016 Sep;54(9):1503-12. doi: 10.3109/13880209.2015.1107104. Epub 2016 Jan 20.

10.

Breast cancer amelioration by Butea monosperma in-vitro and in-vivo.

Karia P, Patel KV, Rathod SSP.

J Ethnopharmacol. 2018 May 10;217:54-62. doi: 10.1016/j.jep.2017.12.026. Epub 2018 Jan 31.

PMID:
29366766
11.

Flavokawain B, a kava chalcone, induces apoptosis in synovial sarcoma cell lines.

Sakai T, Eskander RN, Guo Y, Kim KJ, Mefford J, Hopkins J, Bhatia NN, Zi X, Hoang BH.

J Orthop Res. 2012 Jul;30(7):1045-50. doi: 10.1002/jor.22050. Epub 2011 Dec 29.

12.

Morin, a flavonoid from Moraceae, suppresses growth and invasion of the highly metastatic breast cancer cell line MDA-MB‑231 partly through suppression of the Akt pathway.

Jin H, Lee WS, Eun SY, Jung JH, Park HS, Kim G, Choi YH, Ryu CH, Jung JM, Hong SC, Shin SC, Kim HJ.

Int J Oncol. 2014 Oct;45(4):1629-37. doi: 10.3892/ijo.2014.2535. Epub 2014 Jul 4.

PMID:
24993541
13.

Cucurbitacin B inhibits human breast cancer cell proliferation through disruption of microtubule polymerization and nucleophosmin/B23 translocation.

Duangmano S, Sae-Lim P, Suksamrarn A, Domann FE, Patmasiriwat P.

BMC Complement Altern Med. 2012 Oct 12;12:185. doi: 10.1186/1472-6882-12-185.

14.

Cimicifuga racemosa extract inhibits proliferation of estrogen receptor-positive and negative human breast carcinoma cell lines by induction of apoptosis.

Hostanska K, Nisslein T, Freudenstein J, Reichling J, Saller R.

Breast Cancer Res Treat. 2004 Mar;84(2):151-60.

PMID:
14999145
15.

Cytotoxic activity of extracts and crude saponins from Zanthoxylum armatum DC. against human breast (MCF-7, MDA-MB-468) and colorectal (Caco-2) cancer cell lines.

Alam F, Najum Us Saqib Q, Waheed A.

BMC Complement Altern Med. 2017 Jul 17;17(1):368. doi: 10.1186/s12906-017-1882-1.

16.

Therapeutic effects of matrine on primary and metastatic breast cancer.

Li H, Tan G, Jiang X, Qiao H, Pan S, Jiang H, Kanwar JR, Sun X.

Am J Chin Med. 2010;38(6):1115-30.

PMID:
21061465
17.

Flavokawain B, the hepatotoxic constituent from kava root, induces GSH-sensitive oxidative stress through modulation of IKK/NF-kappaB and MAPK signaling pathways.

Zhou P, Gross S, Liu JH, Yu BY, Feng LL, Nolta J, Sharma V, Piwnica-Worms D, Qiu SX.

FASEB J. 2010 Dec;24(12):4722-32. doi: 10.1096/fj.10-163311. Epub 2010 Aug 9.

18.

Anti-breast cancer effects and mechanisms of Xihuang pill on human breast cancer cell lines.

Pan G, Wang W, Wang L, Zhang F, Yin X, Wang J, Liang R.

J Tradit Chin Med. 2013 Dec;33(6):770-8.

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