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Items: 1 to 20 of 100

1.

ER Adaptor SCAP Translocates and Recruits IRF3 to Perinuclear Microsome Induced by Cytosolic Microbial DNAs.

Chen W, Li S, Yu H, Liu X, Huang L, Wang Q, Liu H, Cui Y, Tang Y, Zhang P, Wang C.

PLoS Pathog. 2016 Feb 22;12(2):e1005462. doi: 10.1371/journal.ppat.1005462. eCollection 2016 Feb.

2.

The E3 ubiquitin ligase AMFR and INSIG1 bridge the activation of TBK1 kinase by modifying the adaptor STING.

Wang Q, Liu X, Cui Y, Tang Y, Chen W, Li S, Yu H, Pan Y, Wang C.

Immunity. 2014 Dec 18;41(6):919-33. doi: 10.1016/j.immuni.2014.11.011. Epub 2014 Nov 28.

3.

STING specifies IRF3 phosphorylation by TBK1 in the cytosolic DNA signaling pathway.

Tanaka Y, Chen ZJ.

Sci Signal. 2012 Mar 6;5(214):ra20. doi: 10.1126/scisignal.2002521.

4.

The binding of TBK1 to STING requires exocytic membrane traffic from the ER.

Ogawa E, Mukai K, Saito K, Arai H, Taguchi T.

Biochem Biophys Res Commun. 2018 Sep 3;503(1):138-145. doi: 10.1016/j.bbrc.2018.05.199. Epub 2018 Jun 7.

PMID:
29870684
5.

Yersinia YopJ negatively regulates IRF3-mediated antibacterial response through disruption of STING-mediated cytosolic DNA signaling.

Cao Y, Guan K, He X, Wei C, Zheng Z, Zhang Y, Ma S, Zhong H, Shi W.

Biochim Biophys Acta. 2016 Dec;1863(12):3148-3159. doi: 10.1016/j.bbamcr.2016.10.004. Epub 2016 Oct 11. Erratum in: Biochim Biophys Acta. 2017 Oct;1864(10 ):1921.

6.

Activation of stimulator of interferon genes (STING) induces ADAM17-mediated shedding of the immune semaphorin SEMA4D.

Motani K, Kosako H.

J Biol Chem. 2018 May 18;293(20):7717-7726. doi: 10.1074/jbc.RA118.002175. Epub 2018 Apr 4.

7.

Cytosolic-DNA-mediated, STING-dependent proinflammatory gene induction necessitates canonical NF-κB activation through TBK1.

Abe T, Barber GN.

J Virol. 2014 May;88(10):5328-41. doi: 10.1128/JVI.00037-14. Epub 2014 Mar 5.

8.

The STING in the tail for cytosolic DNA-dependent activation of IRF3.

Bowie A.

Sci Signal. 2012 Mar 6;5(214):pe9. doi: 10.1126/scisignal.2002919.

PMID:
22394560
9.

Identification of a negative feedback loop between cyclic di-GMP-induced levels of IFI16 and p202 cytosolic DNA sensors and STING.

Panchanathan R, Liu H, Xin D, Choubey D.

Innate Immun. 2014 Oct;20(7):751-9. doi: 10.1177/1753425913507097. Epub 2013 Oct 16.

PMID:
24131791
10.

S6K-STING interaction regulates cytosolic DNA-mediated activation of the transcription factor IRF3.

Wang F, Alain T, Szretter KJ, Stephenson K, Pol JG, Atherton MJ, Hoang HD, Fonseca BD, Zakaria C, Chen L, Rangwala Z, Hesch A, Chan ESY, Tuinman C, Suthar MS, Jiang Z, Ashkar AA, Thomas G, Kozma SC, Gale M Jr, Fitzgerald KA, Diamond MS, Mossman K, Sonenberg N, Wan Y, Lichty BD.

Nat Immunol. 2016 May;17(5):514-522. doi: 10.1038/ni.3433. Epub 2016 Apr 4.

11.

Herpes Simplex Virus 1 Serine Protease VP24 Blocks the DNA-Sensing Signal Pathway by Abrogating Activation of Interferon Regulatory Factor 3.

Zhang D, Su C, Zheng C.

J Virol. 2016 May 27;90(12):5824-5829. doi: 10.1128/JVI.00186-16. Print 2016 Jun 15.

12.

Endoplasmic Reticulum Transmembrane Proteins ZDHHC1 and STING Both Act as Direct Adaptors for IRF3 Activation in Teleost.

Xu X, Li M, Wu Z, Wang H, Wang L, Huang K, Liu X, Hou Q, Lin G, Hu C.

J Immunol. 2017 Nov 15;199(10):3623-3633. doi: 10.4049/jimmunol.1700750. Epub 2017 Oct 18.

13.

STING-IRF3 pathway links endoplasmic reticulum stress with hepatocyte apoptosis in early alcoholic liver disease.

Petrasek J, Iracheta-Vellve A, Csak T, Satishchandran A, Kodys K, Kurt-Jones EA, Fitzgerald KA, Szabo G.

Proc Natl Acad Sci U S A. 2013 Oct 8;110(41):16544-9. doi: 10.1073/pnas.1308331110. Epub 2013 Sep 19.

14.

Fatostatin blocks ER exit of SCAP but inhibits cell growth in a SCAP-independent manner.

Shao W, Machamer CE, Espenshade PJ.

J Lipid Res. 2016 Aug;57(8):1564-73. doi: 10.1194/jlr.M069583. Epub 2016 Jun 20.

15.

STING-IRF3 Triggers Endothelial Inflammation in Response to Free Fatty Acid-Induced Mitochondrial Damage in Diet-Induced Obesity.

Mao Y, Luo W, Zhang L, Wu W, Yuan L, Xu H, Song J, Fujiwara K, Abe JI, LeMaire SA, Wang XL, Shen YH.

Arterioscler Thromb Vasc Biol. 2017 May;37(5):920-929. doi: 10.1161/ATVBAHA.117.309017. Epub 2017 Mar 16. Erratum in: Arterioscler Thromb Vasc Biol. 2018 Apr;38(4):e60.

16.

Both STING and MAVS fish orthologs contribute to the induction of interferon mediated by RIG-I.

Biacchesi S, Mérour E, Lamoureux A, Bernard J, Brémont M.

PLoS One. 2012;7(10):e47737. doi: 10.1371/journal.pone.0047737. Epub 2012 Oct 16.

17.

Autophagy induction via STING trafficking is a primordial function of the cGAS pathway.

Gui X, Yang H, Li T, Tan X, Shi P, Li M, Du F, Chen ZJ.

Nature. 2019 Mar;567(7747):262-266. doi: 10.1038/s41586-019-1006-9. Epub 2019 Mar 6.

PMID:
30842662
18.

Sterol regulatory element-binding protein (SREBP) cleavage regulates Golgi-to-endoplasmic reticulum recycling of SREBP cleavage-activating protein (SCAP).

Shao W, Espenshade PJ.

J Biol Chem. 2014 Mar 14;289(11):7547-57. doi: 10.1074/jbc.M113.545699. Epub 2014 Jan 29.

19.

Nontypeable Haemophilus influenzae DNA stimulates type I interferon expression via STING signaling pathway.

Lu C, Zhang X, Ma C, Xu W, Gan L, Cui J, Yin Y, Wang H.

Biochim Biophys Acta Mol Cell Res. 2018 Apr;1865(4):665-673. doi: 10.1016/j.bbamcr.2018.01.011. Epub 2018 Feb 5.

20.

Enhanced SCAP glycosylation by inflammation induces macrophage foam cell formation.

Zhou C, Lei H, Chen Y, Liu Q, Li LC, Moorhead JF, Varghese Z, Ruan XZ.

PLoS One. 2013 Oct 16;8(10):e75650. doi: 10.1371/journal.pone.0075650. eCollection 2013.

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