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Items: 1 to 20 of 273


Selective labelling and eradication of antibiotic-tolerant bacterial populations in Pseudomonas aeruginosa biofilms.

Chua SL, Yam JK, Hao P, Adav SS, Salido MM, Liu Y, Givskov M, Sze SK, Tolker-Nielsen T, Yang L.

Nat Commun. 2016 Feb 19;7:10750. doi: 10.1038/ncomms10750.


Impairment of Pseudomonas aeruginosa Biofilm Resistance to Antibiotics by Combining the Drugs with a New Quorum-Sensing Inhibitor.

Furiga A, Lajoie B, El Hage S, Baziard G, Roques C.

Antimicrob Agents Chemother. 2015 Dec 28;60(3):1676-86. doi: 10.1128/AAC.02533-15.


Differentiation and distribution of colistin- and sodium dodecyl sulfate-tolerant cells in Pseudomonas aeruginosa biofilms.

Haagensen JA, Klausen M, Ernst RK, Miller SI, Folkesson A, Tolker-Nielsen T, Molin S.

J Bacteriol. 2007 Jan;189(1):28-37. Epub 2006 Oct 13.


In Vitro and In Vivo Efficacy of an LpxC Inhibitor, CHIR-090, Alone or Combined with Colistin against Pseudomonas aeruginosa Biofilm.

Tan JH, Vidaillac C, Yam JKH, Chua SL, Givskov M, Yang L.

Antimicrob Agents Chemother. 2017 Jun 27;61(7). pii: e02223-16. doi: 10.1128/AAC.02223-16. Print 2017 Jul.


Bioavailability-enhanced Resveramax™ modulates quorum sensing and inhibits biofilm formation in Pseudomonas aeruginosa PAO1.

Vasavi HS, Sudeep HV, Lingaraju HB, Shyam Prasad K.

Microb Pathog. 2017 Mar;104:64-71. doi: 10.1016/j.micpath.2017.01.015. Epub 2017 Jan 5.


Selective Proteomic Analysis of Antibiotic-Tolerant Cellular Subpopulations in Pseudomonas aeruginosa Biofilms.

Babin BM, Atangcho L, van Eldijk MB, Sweredoski MJ, Moradian A, Hess S, Tolker-Nielsen T, Newman DK, Tirrell DA.

MBio. 2017 Oct 24;8(5). pii: e01593-17. doi: 10.1128/mBio.01593-17.


Increased bactericidal activity of colistin on Pseudomonas aeruginosa biofilms in anaerobic conditions.

Kolpen M, Appeldorff CF, Brandt S, Mousavi N, Kragh KN, Aydogan S, Uppal HA, Bjarnsholt T, Ciofu O, Høiby N, Jensen PØ.

Pathog Dis. 2016 Feb;74(1):ftv086. doi: 10.1093/femspd/ftv086. Epub 2015 Oct 12.


Nutrient dispersion enhances conventional antibiotic activity against Pseudomonas aeruginosa biofilms.

Sommerfeld Ross S, Fiegel J.

Int J Antimicrob Agents. 2012 Aug;40(2):177-81. doi: 10.1016/j.ijantimicag.2012.04.015. Epub 2012 Jun 22.


A Low-Molecular-Weight Alginate Oligosaccharide Disrupts Pseudomonal Microcolony Formation and Enhances Antibiotic Effectiveness.

Pritchard MF, Powell LC, Jack AA, Powell K, Beck K, Florance H, Forton J, Rye PD, Dessen A, Hill KE, Thomas DW.

Antimicrob Agents Chemother. 2017 Aug 24;61(9). pii: e00762-17. doi: 10.1128/AAC.00762-17. Print 2017 Sep.


Activity of colistin combined with doripenem at clinically relevant concentrations against multidrug-resistant Pseudomonas aeruginosa in an in vitro dynamic biofilm model.

Lora-Tamayo J, Murillo O, Bergen PJ, Nation RL, Poudyal A, Luo X, Yu HY, Ariza J, Li J.

J Antimicrob Chemother. 2014 Sep;69(9):2434-42. doi: 10.1093/jac/dku151. Epub 2014 May 15.


Targeting quorum sensing in Pseudomonas aeruginosa biofilms: current and emerging inhibitors.

Jakobsen TH, Bjarnsholt T, Jensen PØ, Givskov M, Høiby N.

Future Microbiol. 2013 Jul;8(7):901-21. doi: 10.2217/fmb.13.57. Review.


In-vitro bactericidal activity of colistin against biofilm-associated Pseudomonas aeruginosa and Acinetobacter baumannii.

Cai Y, Wang R, Liang BB, An MM.

J Hosp Infect. 2009 Aug;72(4):368-70. doi: 10.1016/j.jhin.2009.03.013. Epub 2009 May 13. No abstract available.


In vivo pharmacokinetics/pharmacodynamics of colistin and imipenem in Pseudomonas aeruginosa biofilm infection.

Hengzhuang W, Wu H, Ciofu O, Song Z, Høiby N.

Antimicrob Agents Chemother. 2012 May;56(5):2683-90. doi: 10.1128/AAC.06486-11. Epub 2012 Feb 21.


In vitro activity of colistin against biofilm by Pseudomonas aeruginosa is significantly improved under "cystic fibrosis-like" physicochemical conditions.

Pompilio A, Crocetta V, Pomponio S, Fiscarelli E, Di Bonaventura G.

Diagn Microbiol Infect Dis. 2015 Aug;82(4):318-25. doi: 10.1016/j.diagmicrobio.2015.01.006. Epub 2015 Jan 23.


Tolerance to the antimicrobial peptide colistin in Pseudomonas aeruginosa biofilms is linked to metabolically active cells, and depends on the pmr and mexAB-oprM genes.

Pamp SJ, Gjermansen M, Johansen HK, Tolker-Nielsen T.

Mol Microbiol. 2008 Apr;68(1):223-40. doi: 10.1111/j.1365-2958.2008.06152.x. Epub 2008 Feb 28.


Evaluation in vitro of the efficacy of colistin methanesulfonate against biofilm-forming multidrug-resistant Pseudomonas aeruginosa (MDRP).

Marumo K, Komukai D, Hirose M, Nakamura H, Tanaka H, Ugajin K, Nagashima G, Yoshimura A.

J Infect Chemother. 2013 Apr;19(2):348-51. doi: 10.1007/s10156-012-0456-x. Epub 2012 Aug 8.


A new synthetic ligand that activates QscR and blocks antibiotic-tolerant biofilm formation in Pseudomonas aeruginosa.

Weng LX, Yang YX, Zhang YQ, Wang LH.

Appl Microbiol Biotechnol. 2014 Mar;98(6):2565-72. doi: 10.1007/s00253-013-5420-x. Epub 2013 Dec 11.


Colistin-tobramycin combinations are superior to monotherapy concerning the killing of biofilm Pseudomonas aeruginosa.

Herrmann G, Yang L, Wu H, Song Z, Wang H, Høiby N, Ulrich M, Molin S, Riethmüller J, Döring G.

J Infect Dis. 2010 Nov 15;202(10):1585-92. doi: 10.1086/656788. Epub 2010 Oct 13.


Pharmacokinetics/pharmacodynamics of colistin and imipenem on mucoid and nonmucoid Pseudomonas aeruginosa biofilms.

Hengzhuang W, Wu H, Ciofu O, Song Z, Høiby N.

Antimicrob Agents Chemother. 2011 Sep;55(9):4469-74. doi: 10.1128/AAC.00126-11. Epub 2011 Jun 13.


The MerR-like regulator BrlR impairs Pseudomonas aeruginosa biofilm tolerance to colistin by repressing PhoPQ.

Chambers JR, Sauer K.

J Bacteriol. 2013 Oct;195(20):4678-88. doi: 10.1128/JB.00834-13. Epub 2013 Aug 9.

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