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Inhibition of the FACT Complex Reduces Transcription from the Human Cytomegalovirus Major Immediate Early Promoter in Models of Lytic and Latent Replication.

O'Connor CM, Nukui M, Gurova KV, Murphy EA.

J Virol. 2016 Mar 28;90(8):4249-4253. doi: 10.1128/JVI.02501-15. Print 2016 Apr.


Chromatin structure regulates human cytomegalovirus gene expression during latency, reactivation and lytic infection.

Sinclair J.

Biochim Biophys Acta. 2010 Mar-Apr;1799(3-4):286-95. doi: 10.1016/j.bbagrm.2009.08.001. Epub 2009 Aug 12. Review.


Control of cytomegalovirus lytic gene expression by histone acetylation.

Murphy JC, Fischle W, Verdin E, Sinclair JH.

EMBO J. 2002 Mar 1;21(5):1112-20.


Human cytomegalovirus G protein-coupled receptor US28 promotes latency by attenuating c-fos.

Krishna BA, Humby MS, Miller WE, O'Connor CM.

Proc Natl Acad Sci U S A. 2019 Jan 29;116(5):1755-1764. doi: 10.1073/pnas.1816933116. Epub 2019 Jan 15.


Regulation of human cytomegalovirus transcription in latency: beyond the major immediate-early promoter.

Reeves M, Sinclair J.

Viruses. 2013 Jun 3;5(6):1395-413. doi: 10.3390/v5061395. Review.


An epistatic relationship between the viral protein kinase UL97 and the UL133-UL138 latency locus during the human cytomegalovirus lytic cycle.

Li G, Rak M, Nguyen CC, Umashankar M, Goodrum FD, Kamil JP.

J Virol. 2014 Jun;88(11):6047-60. doi: 10.1128/JVI.00447-14. Epub 2014 Mar 12.


Latency and reactivation of human cytomegalovirus.

Sinclair J, Sissons P.

J Gen Virol. 2006 Jul;87(Pt 7):1763-79. Review.


Reversible silencing of cytomegalovirus genomes by type I interferon governs virus latency.

Dağ F, Dölken L, Holzki J, Drabig A, Weingärtner A, Schwerk J, Lienenklaus S, Conte I, Geffers R, Davenport C, Rand U, Köster M, Weiß S, Adler B, Wirth D, Messerle M, Hauser H, Cičin-Šain L.

PLoS Pathog. 2014 Feb 20;10(2):e1003962. doi: 10.1371/journal.ppat.1003962. eCollection 2014 Feb.


Chromatin-mediated regulation of cytomegalovirus gene expression.

Reeves MB.

Virus Res. 2011 May;157(2):134-43. doi: 10.1016/j.virusres.2010.09.019. Epub 2010 Sep 25. Review.


Epigenetic control of cytomegalovirus latency and reactivation.

Liu XF, Wang X, Yan S, Zhang Z, Abecassis M, Hummel M.

Viruses. 2013 May 23;5(5):1325-45. doi: 10.3390/v5051325. Review.


Two gamma interferon-activated site-like elements in the human cytomegalovirus major immediate-early promoter/enhancer are important for viral replication.

Netterwald J, Yang S, Wang W, Ghanny S, Cody M, Soteropoulos P, Tian B, Dunn W, Liu F, Zhu H.

J Virol. 2005 Apr;79(8):5035-46.


The human cytomegalovirus-encoded receptor US28 increases the activity of the major immediate-early promoter/enhancer.

Boomker JM, The TH, de Leij LF, Harmsen MC.

Virus Res. 2006 Jun;118(1-2):196-200. Epub 2006 Jan 31.


Multiple Transcripts Encode Full-Length Human Cytomegalovirus IE1 and IE2 Proteins during Lytic Infection.

Arend KC, Ziehr B, Vincent HA, Moorman NJ.

J Virol. 2016 Sep 12;90(19):8855-65. doi: 10.1128/JVI.00741-16. Print 2016 Oct 1.


A myeloid progenitor cell line capable of supporting human cytomegalovirus latency and reactivation, resulting in infectious progeny.

O'Connor CM, Murphy EA.

J Virol. 2012 Sep;86(18):9854-65. doi: 10.1128/JVI.01278-12. Epub 2012 Jul 3.

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