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Items: 20

1.

Bioluminescent imaging of ABCG2 efflux activity at the blood-placenta barrier.

Kumar JS, Wei BR, Madigan JP, Simpson RM, Hall MD, Gottesman MM.

Sci Rep. 2016 Feb 8;6:20418. doi: 10.1038/srep20418.

2.

Bioluminescent imaging of drug efflux at the blood-brain barrier mediated by the transporter ABCG2.

Bakhsheshian J, Wei BR, Chang KE, Shukla S, Ambudkar SV, Simpson RM, Gottesman MM, Hall MD.

Proc Natl Acad Sci U S A. 2013 Dec 17;110(51):20801-6. doi: 10.1073/pnas.1312159110. Epub 2013 Dec 2.

3.

In Vivo Bioluminescent Imaging of ATP-Binding Cassette Transporter-Mediated Efflux at the Blood-Brain Barrier.

Bakhsheshian J, Wei BR, Hall MD, Simpson RM, Gottesman MM.

Methods Mol Biol. 2016;1461:227-39. doi: 10.1007/978-1-4939-3813-1_19.

PMID:
27424909
4.

ABCG2/BCRP expression modulates D-Luciferin based bioluminescence imaging.

Zhang Y, Bressler JP, Neal J, Lal B, Bhang HE, Laterra J, Pomper MG.

Cancer Res. 2007 Oct 1;67(19):9389-97.

5.

Dual inhibitors of the human blood-brain barrier drug efflux transporters P-glycoprotein and ABCG2 based on the antiviral azidothymidine.

Namanja-Magliano HA, Bohn K, Agrawal N, Willoughby ME, Hrycyna CA, Chmielewski J.

Bioorg Med Chem. 2017 Oct 1;25(19):5128-5132. doi: 10.1016/j.bmc.2017.07.001. Epub 2017 Jul 6.

PMID:
28712845
6.

Gemcitabine upregulates ABCG2/BCRP and modulates the intracellular pharmacokinetic profiles of bioluminescence in pancreatic cancer cells.

Sun Y, Gu M, Zhu L, Liu J, Xiong Y, Wei Y, Li F.

Anticancer Drugs. 2016 Mar;27(3):183-91. doi: 10.1097/CAD.0000000000000315.

PMID:
26556627
7.

The ABCG2 efflux transporter from rabbit placenta: Cloning and functional characterization.

Halwachs S, Kneuer C, Gohlsch K, Müller M, Ritz V, Honscha W.

Placenta. 2016 Feb;38:8-15. doi: 10.1016/j.placenta.2015.12.005. Epub 2015 Dec 12.

8.

Dual Modulation of Human P-Glycoprotein and ABCG2 with Prodrug Dimers of the Atypical Antipsychotic Agent Paliperidone in a Model of the Blood-Brain Barrier.

Bohn K, Lange A, Chmielewski J, Hrycyna CA.

Mol Pharm. 2017 Apr 3;14(4):1107-1119. doi: 10.1021/acs.molpharmaceut.6b01044. Epub 2017 Mar 21.

PMID:
28264565
9.

Assessment of ABCG2-mediated transport of pesticides across the rabbit placenta barrier using a novel MDCKII in vitro model.

Halwachs S, Schäfer I, Kneuer C, Seibel P, Honscha W.

Toxicol Appl Pharmacol. 2016 Aug 15;305:66-74. doi: 10.1016/j.taap.2016.06.007. Epub 2016 Jun 8.

10.

What next? Preferably development of drugs that are no longer transported by the ABCB1 and ABCG2 efflux transporters.

van Hoppe S, Schinkel AH.

Pharmacol Res. 2017 Sep;123:144. doi: 10.1016/j.phrs.2017.05.015. Epub 2017 May 31. No abstract available.

PMID:
28578203
11.
12.

Uptake kinetics and biodistribution of 14C-D-luciferin--a radiolabeled substrate for the firefly luciferase catalyzed bioluminescence reaction: impact on bioluminescence based reporter gene imaging.

Berger F, Paulmurugan R, Bhaumik S, Gambhir SS.

Eur J Nucl Med Mol Imaging. 2008 Dec;35(12):2275-85. doi: 10.1007/s00259-008-0870-6. Epub 2008 Jul 26.

13.

Influence of bioluminescence imaging dynamics by D-luciferin uptake and efflux mechanisms.

Zhang Y, Pullambhatla M, Laterra J, Pomper MG.

Mol Imaging. 2012 Nov-Dec;11(6):499-506.

14.

Pregnane X receptor upregulates ABC-transporter Abcg2 and Abcb1 at the blood-brain barrier.

Lemmen J, Tozakidis IE, Galla HJ.

Brain Res. 2013 Jan 23;1491:1-13. doi: 10.1016/j.brainres.2012.10.060. Epub 2012 Nov 2.

PMID:
23123212
15.

Luciferins behave like drugs.

Mofford DM, Miller SC.

ACS Chem Neurosci. 2015 Aug 19;6(8):1273-5. doi: 10.1021/acschemneuro.5b00195. Epub 2015 Jul 30.

PMID:
26225810
16.

Down-regulation of ABCG2 and ABCB4 transporters in the placenta of rats exposed to cadmium.

Liu L, Zhou L, Hu S, Zhou S, Deng Y, Dong M, Huang J, Zeng Y, Chen X, Zhao N, Li H, Ding Z.

Oncotarget. 2016 Jun 21;7(25):38154-38163. doi: 10.18632/oncotarget.9415.

17.

Repression of adenosine triphosphate-binding cassette transporter ABCG2 by estrogen increases intracellular glutathione in brain endothelial cells following ischemic reperfusion injury.

Shin JA, Jeong SI, Kim HW, Jang G, Ryu DR, Ahn YH, Choi JH, Choi YH, Park EM.

Neurobiol Aging. 2018 Jun;66:138-148. doi: 10.1016/j.neurobiolaging.2018.02.020. Epub 2018 Feb 27.

PMID:
29574357
18.

In Vivo Imaging of Human MDR1 Transcription in the Brain and Spine of MDR1-Luciferase Reporter Mice.

Yasuda K, Cline C, Lin YS, Scheib R, Ganguly S, Thirumaran RK, Chaudhry A, Kim RB, Schuetz EG.

Drug Metab Dispos. 2015 Nov;43(11):1646-54. doi: 10.1124/dmd.115.065078. Epub 2015 Aug 17.

19.

Drug transporters: gatekeepers controlling access of xenobiotics to the cellular interior.

Stanley LA, Horsburgh BC, Ross J, Scheer N, Wolf CR.

Drug Metab Rev. 2009;41(1):27-65. doi: 10.1080/03602530802605040. Review.

PMID:
19514970
20.

In Vitro Models for Studying Transport Across Epithelial Tissue Barriers.

Arumugasaamy N, Navarro J, Kent Leach J, Kim PCW, Fisher JP.

Ann Biomed Eng. 2019 Jan;47(1):1-21. doi: 10.1007/s10439-018-02124-w. Epub 2018 Sep 14. Review.

PMID:
30218224

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