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Items: 1 to 20 of 106

1.

Molecular and Cellular Profiling of Scalp Psoriasis Reveals Differences and Similarities Compared to Skin Psoriasis.

Ruano J, Suárez-Fariñas M, Shemer A, Oliva M, Guttman-Yassky E, Krueger JG.

PLoS One. 2016 Feb 5;11(2):e0148450. doi: 10.1371/journal.pone.0148450. eCollection 2016.

2.

Alopecia areata profiling shows TH1, TH2, and IL-23 cytokine activation without parallel TH17/TH22 skewing.

Suárez-Fariñas M, Ungar B, Noda S, Shroff A, Mansouri Y, Fuentes-Duculan J, Czernik A, Zheng X, Estrada YD, Xu H, Peng X, Shemer A, Krueger JG, Lebwohl MG, Guttman-Yassky E.

J Allergy Clin Immunol. 2015 Nov;136(5):1277-87. doi: 10.1016/j.jaci.2015.06.032. Epub 2015 Aug 24.

PMID:
26316095
3.

Characterization and profiling of immunomodulatory genes in resident mesenchymal stem cells reflect the Th1-Th17/Th2 imbalance of psoriasis.

Campanati A, Orciani M, Consales V, Lazzarini R, Ganzetti G, Di Benedetto G, Di Primio R, Offidani A.

Arch Dermatol Res. 2014 Dec;306(10):915-20. doi: 10.1007/s00403-014-1493-3. Epub 2014 Aug 27.

PMID:
25160906
4.

RNA-seq identifies a diminished differentiation gene signature in primary monolayer keratinocytes grown from lesional and uninvolved psoriatic skin.

Swindell WR, Sarkar MK, Liang Y, Xing X, Baliwag J, Elder JT, Johnston A, Ward NL, Gudjonsson JE.

Sci Rep. 2017 Dec 22;7(1):18045. doi: 10.1038/s41598-017-18404-9.

5.

Gene expression profiles normalized in psoriatic skin by treatment with brodalumab, a human anti-IL-17 receptor monoclonal antibody.

Russell CB, Rand H, Bigler J, Kerkof K, Timour M, Bautista E, Krueger JG, Salinger DH, Welcher AA, Martin DA.

J Immunol. 2014 Apr 15;192(8):3828-36. doi: 10.4049/jimmunol.1301737. Epub 2014 Mar 19.

6.

Cytokine network in psoriasis revisited.

Michalak-Stoma A, Pietrzak A, Szepietowski JC, Zalewska-Janowska A, Paszkowski T, Chodorowska G.

Eur Cytokine Netw. 2011 Dec;22(4):160-8. doi: 10.1684/ecn.2011.0294. Review.

7.

The Keratinocyte Transcriptome in Psoriasis: Pathways Related to Immune Responses, Cell Cycle and Keratinization.

Pasquali L, Srivastava A, Meisgen F, Das Mahapatra K, Xia P, Xu Landén N, Pivarcsi A, Sonkoly E.

Acta Derm Venereol. 2019 Feb 1;99(2):196-205. doi: 10.2340/00015555-3066.

8.

Dissecting the psoriasis transcriptome: inflammatory- and cytokine-driven gene expression in lesions from 163 patients.

Swindell WR, Johnston A, Voorhees JJ, Elder JT, Gudjonsson JE.

BMC Genomics. 2013 Aug 1;14:527. doi: 10.1186/1471-2164-14-527.

9.

A single intradermal injection of IFN-γ induces an inflammatory state in both non-lesional psoriatic and healthy skin.

Johnson-Huang LM, Suárez-Fariñas M, Pierson KC, Fuentes-Duculan J, Cueto I, Lentini T, Sullivan-Whalen M, Gilleaudeau P, Krueger JG, Haider AS, Lowes MA.

J Invest Dermatol. 2012 Apr;132(4):1177-87. doi: 10.1038/jid.2011.458. Epub 2012 Jan 26.

10.

Psoriasis in humans is associated with down-regulation of galectins in dendritic cells.

de la Fuente H, Perez-Gala S, Bonay P, Cruz-Adalia A, Cibrian D, Sanchez-Cuellar S, Dauden E, Fresno M, García-Diez A, Sanchez-Madrid F.

J Pathol. 2012 Oct;228(2):193-203. doi: 10.1002/path.3996. Epub 2012 Mar 22.

PMID:
22271227
11.

Th17 cytokines interleukin (IL)-17 and IL-22 modulate distinct inflammatory and keratinocyte-response pathways.

Nograles KE, Zaba LC, Guttman-Yassky E, Fuentes-Duculan J, Suárez-Fariñas M, Cardinale I, Khatcherian A, Gonzalez J, Pierson KC, White TR, Pensabene C, Coats I, Novitskaya I, Lowes MA, Krueger JG.

Br J Dermatol. 2008 Nov;159(5):1092-102. doi: 10.1111/j.1365-2133.2008.08769.x. Epub 2008 Aug 5.

12.

CD8(+) T cells mediate RAS-induced psoriasis-like skin inflammation through IFN-γ.

Gunderson AJ, Mohammed J, Horvath FJ, Podolsky MA, Anderson CR, Glick AB.

J Invest Dermatol. 2013 Apr;133(4):955-63. doi: 10.1038/jid.2012.390. Epub 2012 Nov 15.

13.

Th1, Th2, Th17 and regulatory T cell pattern in psoriatic patients: modulation of cytokines and gene targets induced by etanercept treatment and correlation with clinical response.

Quaglino P, Bergallo M, Ponti R, Barberio E, Cicchelli S, Buffa E, Comessatti A, Costa C, Terlizzi ME, Astegiano S, Novelli M, Cavallo R, Bernengo MG.

Dermatology. 2011;223(1):57-67. doi: 10.1159/000330330. Epub 2011 Aug 25.

14.

The Asian atopic dermatitis phenotype combines features of atopic dermatitis and psoriasis with increased TH17 polarization.

Noda S, Suárez-Fariñas M, Ungar B, Kim SJ, de Guzman Strong C, Xu H, Peng X, Estrada YD, Nakajima S, Honda T, Shin JU, Lee H, Krueger JG, Lee KH, Kabashima K, Guttman-Yassky E.

J Allergy Clin Immunol. 2015 Nov;136(5):1254-64. doi: 10.1016/j.jaci.2015.08.015. Epub 2015 Oct 1.

PMID:
26428954
15.

Transcriptome profiling unveils the role of cholesterol in IL-17A signaling in psoriasis.

Varshney P, Narasimhan A, Mittal S, Malik G, Sardana K, Saini N.

Sci Rep. 2016 Jan 19;6:19295. doi: 10.1038/srep19295.

16.

Guselkumab (an IL-23-specific mAb) demonstrates clinical and molecular response in patients with moderate-to-severe psoriasis.

Sofen H, Smith S, Matheson RT, Leonardi CL, Calderon C, Brodmerkel C, Li K, Campbell K, Marciniak SJ Jr, Wasfi Y, Wang Y, Szapary P, Krueger JG.

J Allergy Clin Immunol. 2014 Apr;133(4):1032-40. doi: 10.1016/j.jaci.2014.01.025.

17.

GATA3 expression is decreased in psoriasis and during epidermal regeneration; induction by narrow-band UVB and IL-4.

Rácz E, Kurek D, Kant M, Baerveldt EM, Florencia E, Mourits S, de Ridder D, Laman JD, van der Fits L, Prens EP.

PLoS One. 2011;6(5):e19806. doi: 10.1371/journal.pone.0019806. Epub 2011 May 17.

18.

Streptococcus pyogenes-induced cutaneous lymphocyte antigen-positive T cell-dependent epidermal cell activation triggers TH17 responses in patients with guttate psoriasis.

Ruiz-Romeu E, Ferran M, Sagristà M, Gómez J, Giménez-Arnau A, Herszenyi K, Hóllo P, Celada A, Pujol R, Santamaria-Babí LF.

J Allergy Clin Immunol. 2016 Aug;138(2):491-499.e6. doi: 10.1016/j.jaci.2016.02.008. Epub 2016 Apr 4.

PMID:
27056267
19.

RNA-seq and flow-cytometry of conventional, scalp, and palmoplantar psoriasis reveal shared and distinct molecular pathways.

Ahn R, Yan D, Chang HW, Lee K, Bhattarai S, Huang ZM, Nakamura M, Singh R, Afifi L, Taravati K, Munoz-Sandoval P, Pauli M, Rosenblum MD, Liao W.

Sci Rep. 2018 Jul 27;8(1):11368. doi: 10.1038/s41598-018-29472-w.

20.

Down-regulation of the Th1, Th17, and Th22 pathways due to anti-TNF-α treatment in psoriasis.

Luan L, Han S, Wang H, Liu X.

Int Immunopharmacol. 2015 Dec;29(2):278-284. doi: 10.1016/j.intimp.2015.11.005. Epub 2015 Nov 12.

PMID:
26585971

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