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Items: 1 to 20 of 66

1.

Genetic variants near MLST8 and DHX57 affect the epigenetic age of the cerebellum.

Lu AT, Hannon E, Levine ME, Hao K, Crimmins EM, Lunnon K, Kozlenkov A, Mill J, Dracheva S, Horvath S.

Nat Commun. 2016 Feb 2;7:10561. doi: 10.1038/ncomms10561.

2.

The cerebellum ages slowly according to the epigenetic clock.

Horvath S, Mah V, Lu AT, Woo JS, Choi OW, Jasinska AJ, Riancho JA, Tung S, Coles NS, Braun J, Vinters HV, Coles LS.

Aging (Albany NY). 2015 May;7(5):294-306.

3.

Genetic architecture of epigenetic and neuronal ageing rates in human brain regions.

Lu AT, Hannon E, Levine ME, Crimmins EM, Lunnon K, Mill J, Geschwind DH, Horvath S.

Nat Commun. 2017 May 18;8:15353. doi: 10.1038/ncomms15353.

4.
5.

Genetic and epigenetic variants contributing to clofarabine cytotoxicity.

Eadon MT, Wheeler HE, Stark AL, Zhang X, Moen EL, Delaney SM, Im HK, Cunningham PN, Zhang W, Dolan ME.

Hum Mol Genet. 2013 Oct 1;22(19):4007-20. doi: 10.1093/hmg/ddt240. Epub 2013 May 29.

6.

Meta-analysis for genome-wide association study identifies multiple variants at the BIN1 locus associated with late-onset Alzheimer's disease.

Hu X, Pickering E, Liu YC, Hall S, Fournier H, Katz E, Dechairo B, John S, Van Eerdewegh P, Soares H; Alzheimer's Disease Neuroimaging Initiative.

PLoS One. 2011 Feb 24;6(2):e16616. doi: 10.1371/journal.pone.0016616.

7.

Differential DNA methylation identified in the blood and retina of AMD patients.

Oliver VF, Jaffe AE, Song J, Wang G, Zhang P, Branham KE, Swaroop A, Eberhart CG, Zack DJ, Qian J, Merbs SL.

Epigenetics. 2015;10(8):698-707. doi: 10.1080/15592294.2015.1060388.

8.

Endometrial vezatin and its association with endometriosis risk.

Holdsworth-Carson SJ, Fung JN, Luong HT, Sapkota Y, Bowdler LM, Wallace L, Teh WT, Powell JE, Girling JE, Healey M, Montgomery GW, Rogers PA.

Hum Reprod. 2016 May;31(5):999-1013. doi: 10.1093/humrep/dew047. Epub 2016 Mar 22.

PMID:
27005890
9.
10.

Genome-wide associations between genetic and epigenetic variation influence mRNA expression and insulin secretion in human pancreatic islets.

Olsson AH, Volkov P, Bacos K, Dayeh T, Hall E, Nilsson EA, Ladenvall C, Rönn T, Ling C.

PLoS Genet. 2014 Nov 6;10(11):e1004735. doi: 10.1371/journal.pgen.1004735. eCollection 2014 Nov. Erratum in: PLoS Genet. 2014 Dec;10(12):e1004886.

11.

Human aging in the post-GWAS era: further insights reveal potential regulatory variants.

Haider SA, Faisal M.

Biogerontology. 2015 Aug;16(4):529-41. doi: 10.1007/s10522-015-9575-y. Epub 2015 Apr 17.

PMID:
25895066
12.

Menopause accelerates biological aging.

Levine ME, Lu AT, Chen BH, Hernandez DG, Singleton AB, Ferrucci L, Bandinelli S, Salfati E, Manson JE, Quach A, Kusters CD, Kuh D, Wong A, Teschendorff AE, Widschwendter M, Ritz BR, Absher D, Assimes TL, Horvath S.

Proc Natl Acad Sci U S A. 2016 Aug 16;113(33):9327-32. doi: 10.1073/pnas.1604558113. Epub 2016 Jul 25.

13.

Genome-wide association of familial late-onset Alzheimer's disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE.

Wijsman EM, Pankratz ND, Choi Y, Rothstein JH, Faber KM, Cheng R, Lee JH, Bird TD, Bennett DA, Diaz-Arrastia R, Goate AM, Farlow M, Ghetti B, Sweet RA, Foroud TM, Mayeux R; NIA-LOAD/NCRAD Family Study Group.

PLoS Genet. 2011 Feb;7(2):e1001308. doi: 10.1371/journal.pgen.1001308. Epub 2011 Feb 17.

14.

Epigenetic genome-wide association methylation in aging and longevity.

Ben-Avraham D, Muzumdar RH, Atzmon G.

Epigenomics. 2012 Oct;4(5):503-9. doi: 10.2217/epi.12.41. Review.

15.

Large-scale East-Asian eQTL mapping reveals novel candidate genes for LD mapping and the genomic landscape of transcriptional effects of sequence variants.

Narahara M, Higasa K, Nakamura S, Tabara Y, Kawaguchi T, Ishii M, Matsubara K, Matsuda F, Yamada R.

PLoS One. 2014 Jun 23;9(6):e100924. doi: 10.1371/journal.pone.0100924. eCollection 2014.

16.

Genetics of healthy aging and longevity.

Brooks-Wilson AR.

Hum Genet. 2013 Dec;132(12):1323-38. doi: 10.1007/s00439-013-1342-z. Epub 2013 Aug 8. Review.

17.

SNP-based pathway enrichment analysis for genome-wide association studies.

Weng L, Macciardi F, Subramanian A, Guffanti G, Potkin SG, Yu Z, Xie X.

BMC Bioinformatics. 2011 Apr 15;12:99. doi: 10.1186/1471-2105-12-99.

18.

[Genetic and epigenetic news in gerontology].

Baranov VS, Glotov OS, Baranova EV.

Adv Gerontol. 2014;27(2):247-56. Review. Russian.

PMID:
25306655
19.

Replication of BIN1 association with Alzheimer's disease and evaluation of genetic interactions.

Carrasquillo MM, Belbin O, Hunter TA, Ma L, Bisceglio GD, Zou F, Crook JE, Pankratz VS, Sando SB, Aasly JO, Barcikowska M, Wszolek ZK, Dickson DW, Graff-Radford NR, Petersen RC, Morgan K, Younkin SG.

J Alzheimers Dis. 2011;24(4):751-8. doi: 10.3233/JAD-2011-101932.

20.

Association of CAD, a multifunctional protein involved in pyrimidine synthesis, with mLST8, a component of the mTOR complexes.

Nakashima A, Kawanishi I, Eguchi S, Yu EH, Eguchi S, Oshiro N, Yoshino K, Kikkawa U, Yonezawa K.

J Biomed Sci. 2013 Apr 18;20:24. doi: 10.1186/1423-0127-20-24.

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