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Items: 1 to 20 of 101

1.

Inactivation of nuclear GSK3β by Ser(389) phosphorylation promotes lymphocyte fitness during DNA double-strand break response.

Thornton TM, Delgado P, Chen L, Salas B, Krementsov D, Fernandez M, Vernia S, Davis RJ, Heimann R, Teuscher C, Krangel MS, Ramiro AR, Rincón M.

Nat Commun. 2016 Jan 29;7:10553. doi: 10.1038/ncomms10553.

2.

Glycogen synthase kinase 3beta inhibition enhances repair of DNA double-strand breaks in irradiated hippocampal neurons.

Yang ES, Nowsheen S, Wang T, Thotala DK, Xia F.

Neuro Oncol. 2011 May;13(5):459-70. doi: 10.1093/neuonc/nor016. Epub 2011 Mar 11.

3.

AMP-activated protein kinase activation increases phosphorylation of glycogen synthase kinase 3beta and thereby reduces cAMP-responsive element transcriptional activity and phosphoenolpyruvate carboxykinase C gene expression in the liver.

Horike N, Sakoda H, Kushiyama A, Ono H, Fujishiro M, Kamata H, Nishiyama K, Uchijima Y, Kurihara Y, Kurihara H, Asano T.

J Biol Chem. 2008 Dec 5;283(49):33902-10. doi: 10.1074/jbc.M802537200. Epub 2008 Sep 17.

4.

Mechanical regulation of glycogen synthase kinase 3β (GSK3β) in mesenchymal stem cells is dependent on Akt protein serine 473 phosphorylation via mTORC2 protein.

Case N, Thomas J, Sen B, Styner M, Xie Z, Galior K, Rubin J.

J Biol Chem. 2011 Nov 11;286(45):39450-6. doi: 10.1074/jbc.M111.265330. Epub 2011 Sep 28.

5.

ATM damage response and XLF repair factor are functionally redundant in joining DNA breaks.

Zha S, Guo C, Boboila C, Oksenych V, Cheng HL, Zhang Y, Wesemann DR, Yuen G, Patel H, Goff PH, Dubois RL, Alt FW.

Nature. 2011 Jan 13;469(7329):250-4. doi: 10.1038/nature09604. Epub 2010 Dec 15.

6.
7.

Phosphorylation and inactivation of glycogen synthase kinase 3β (GSK3β) by dual-specificity tyrosine phosphorylation-regulated kinase 1A (Dyrk1A).

Song WJ, Song EA, Jung MS, Choi SH, Baik HH, Jin BK, Kim JH, Chung SH.

J Biol Chem. 2015 Jan 23;290(4):2321-33. doi: 10.1074/jbc.M114.594952. Epub 2014 Dec 4.

8.

PAXX and XLF DNA repair factors are functionally redundant in joining DNA breaks in a G1-arrested progenitor B-cell line.

Kumar V, Alt FW, Frock RL.

Proc Natl Acad Sci U S A. 2016 Sep 20;113(38):10619-24. doi: 10.1073/pnas.1611882113. Epub 2016 Sep 6.

9.

ERK1/2 antagonizes glycogen synthase kinase-3beta-induced apoptosis in cortical neurons.

Hetman M, Hsuan SL, Habas A, Higgins MJ, Xia Z.

J Biol Chem. 2002 Dec 20;277(51):49577-84. Epub 2002 Oct 21.

10.

Functional overlaps between XLF and the ATM-dependent DNA double strand break response.

Kumar V, Alt FW, Oksenych V.

DNA Repair (Amst). 2014 Apr;16:11-22. doi: 10.1016/j.dnarep.2014.01.010. Epub 2014 Feb 20. Review.

11.

Artemis-independent functions of DNA-dependent protein kinase in Ig heavy chain class switch recombination and development.

Rooney S, Alt FW, Sekiguchi J, Manis JP.

Proc Natl Acad Sci U S A. 2005 Feb 15;102(7):2471-5. Epub 2005 Feb 7.

12.

Developmental propagation of V(D)J recombination-associated DNA breaks and translocations in mature B cells via dicentric chromosomes.

Hu J, Tepsuporn S, Meyers RM, Gostissa M, Alt FW.

Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):10269-74. doi: 10.1073/pnas.1410112111. Epub 2014 Jun 30.

13.

Glycogen synthase kinase 3beta is a novel regulator of high glucose- and high insulin-induced extracellular matrix protein synthesis in renal proximal tubular epithelial cells.

Mariappan MM, Shetty M, Sataranatarajan K, Choudhury GG, Kasinath BS.

J Biol Chem. 2008 Nov 7;283(45):30566-75. doi: 10.1074/jbc.M801756200. Epub 2008 Aug 12.

14.

Phosphorylation by p38 MAPK as an alternative pathway for GSK3beta inactivation.

Thornton TM, Pedraza-Alva G, Deng B, Wood CD, Aronshtam A, Clements JL, Sabio G, Davis RJ, Matthews DE, Doble B, Rincon M.

Science. 2008 May 2;320(5876):667-70. doi: 10.1126/science.1156037.

15.

Nuclear GSK3β induces DNA double-strand break repair by phosphorylating 53BP1 in glioblastoma.

Yang Y, Lei T, Du S, Tong R, Wang H, Yang J, Huang J, Sun M, Wang Y, Dong Z.

Int J Oncol. 2018 Mar;52(3):709-720. doi: 10.3892/ijo.2018.4237. Epub 2018 Jan 4.

16.

Orientation-specific joining of AID-initiated DNA breaks promotes antibody class switching.

Dong J, Panchakshari RA, Zhang T, Zhang Y, Hu J, Volpi SA, Meyers RM, Ho YJ, Du Z, Robbiani DF, Meng F, Gostissa M, Nussenzweig MC, Manis JP, Alt FW.

Nature. 2015 Sep 3;525(7567):134-139. doi: 10.1038/nature14970. Epub 2015 Aug 26.

17.

Essential role for DNA-PKcs in DNA double-strand break repair and apoptosis in ATM-deficient lymphocytes.

Callén E, Jankovic M, Wong N, Zha S, Chen HT, Difilippantonio S, Di Virgilio M, Heidkamp G, Alt FW, Nussenzweig A, Nussenzweig M.

Mol Cell. 2009 May 15;34(3):285-97. doi: 10.1016/j.molcel.2009.04.025.

18.

Endonuclease G plays a role in immunoglobulin class switch DNA recombination by introducing double-strand breaks in switch regions.

Zan H, Zhang J, Al-Qahtani A, Pone EJ, White CA, Lee D, Yel L, Mai T, Casali P.

Mol Immunol. 2011 Jan;48(4):610-22. doi: 10.1016/j.molimm.2010.10.023. Epub 2010 Nov 26.

19.

Glycogen synthase kinase 3β represses MYOGENIN function in alveolar rhabdomyosarcoma.

Dionyssiou MG, Ehyai S, Avrutin E, Connor MK, McDermott JC.

Cell Death Dis. 2014 Feb 27;5:e1094. doi: 10.1038/cddis.2014.58.

20.

Functional intersection of ATM and DNA-dependent protein kinase catalytic subunit in coding end joining during V(D)J recombination.

Lee BS, Gapud EJ, Zhang S, Dorsett Y, Bredemeyer A, George R, Callen E, Daniel JA, Osipovich O, Oltz EM, Bassing CH, Nussenzweig A, Lees-Miller S, Hammel M, Chen BP, Sleckman BP.

Mol Cell Biol. 2013 Sep;33(18):3568-79. doi: 10.1128/MCB.00308-13. Epub 2013 Jul 8.

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